• Artifact of Baysian analysis

    From RonO@21:1/5 to All on Wed Dec 13 19:58:27 2023
    https://pubmed.ncbi.nlm.nih.gov/37695319/

    The pdf of this article labels it as a point of view article. It is an
    open access article where the authors claim that the greater depth of
    the estimated phylogenetic node than an estimate based on the existing
    fossil record is due to an artifact of the Baysian inference of clade
    origin. It is common knowledge that molecular clock estimates of
    lineage separation is usually older than the first fossils of a new
    branching lineage.

    It sounds like it should be true if you have priors that include the
    oldest known fossils, but I really do not know if the people looking at
    the Cambrian diversification of bilateral animals do that. I haven't
    looked into it for decades, but they used to calibrate the clock using
    related lineages that had a better fossil record that was dated more accurately. You didn't use the nodes that you were trying to estimate,
    but Baysian methods do, do a reiteration from some original estimate.

    Ron Okimoto

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  • From RonO@21:1/5 to RonO on Wed Dec 13 20:28:37 2023
    On 12/13/2023 7:58 PM, RonO wrote:
    https://pubmed.ncbi.nlm.nih.gov/37695319/

    The pdf of this article labels it as a point of view article.  It is an
    open access article where the authors claim that the greater depth of
    the estimated phylogenetic node than an estimate based on the existing
    fossil record is due to an artifact of the Baysian inference of clade origin.  It is common knowledge that molecular clock estimates of
    lineage separation is usually older than the first fossils of a new
    branching lineage.

    It sounds like it should be true if you have priors that include the
    oldest known fossils, but I really do not know if the people looking at
    the Cambrian diversification of bilateral animals do that.  I haven't
    looked into it for decades, but they used to calibrate the clock using related lineages that had a better fossil record that was dated more accurately.  You didn't use the nodes that you were trying to estimate,
    but Baysian methods do, do a reiteration from some original estimate.

    Ron Okimoto


    It might be noted that the human-chimp divergence was estimated to be
    4.5 to 8 million years ago, back in the 1980's and the subsequent
    estimates keep falling within that range. In this case the additional
    fossil evidence that has accumlated has pushed the estimate further into
    the past rather than closer to the 4.5 million year estimate. The
    bipedal fossils are pushing the estimate over 6 million, and I recall
    seeing an 8 million year estimate.

    Ron Okimoto

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  • From RonO@21:1/5 to erik simpson on Thu Dec 14 05:31:59 2023
    On 12/13/2023 9:33 PM, erik simpson wrote:
    On Wednesday, December 13, 2023 at 7:22:08 PM UTC-8, erik simpson wrote:
    On Wednesday, December 13, 2023 at 6:02:08 PM UTC-8, RonO wrote:
    https://pubmed.ncbi.nlm.nih.gov/37695319/

    The pdf of this article labels it as a point of view article. It is an
    open access article where the authors claim that the greater depth of
    the estimated phylogenetic node than an estimate based on the existing
    fossil record is due to an artifact of the Baysian inference of clade
    origin. It is common knowledge that molecular clock estimates of
    lineage separation is usually older than the first fossils of a new
    branching lineage.

    It sounds like it should be true if you have priors that include the
    oldest known fossils, but I really do not know if the people looking at
    the Cambrian diversification of bilateral animals do that. I haven't
    looked into it for decades, but they used to calibrate the clock using
    related lineages that had a better fossil record that was dated more
    accurately. You didn't use the nodes that you were trying to estimate,
    but Baysian methods do, do a reiteration from some original estimate.

    Ron Okimoto
    Bilaterian divergence took place deep in the Ediacaran, but the record is

    pretty sparse. As you say, the best molecular clock estimates should be
    older unless you happened to find a fossil immediately after the divergence.
    After looking some detail at Budd & Mann's paper, I notice that the putative
    discovery of Ediacaran tunicates (https://doi.org/10.1007/s12542-021-00596-1) isn't mentioned. If it is indeed a tunicate, it would indicate the presence of chordates
    557 Mya.


    It is what happened with the Human estimate. We knew that we didn't
    have the fossils closer to the divergence between chimps and humans.
    When we obtained more fossils the divergence started to creep towards
    the older boundary. Now, it is pushing the 8 million year estimate.
    The first clock with a reasonable amount of molecular data indicated 4.5
    to 8 million years for the divergence between chimps and humans, and the
    data favored somewhere around 5 million years, but with additional
    fossils and the desire to claim them as part of our lineage there has
    been a creep to older estimates. The molecular estimate is still within
    the 4.5 to 8 million year range, but it looks like the fossils are
    indicating that it is in the older part of the range. If we used those
    fossils and their dates, you would probably be right in that the age
    would extend further into the past.

    Ron Okimoto

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  • From Bob Casanova@21:1/5 to All on Thu Dec 14 08:58:08 2023
    On Thu, 14 Dec 2023 05:31:59 -0600, the following appeared
    in talk.origins, posted by RonO <rokimoto@cox.net>:

    On 12/13/2023 9:33 PM, erik simpson wrote:
    On Wednesday, December 13, 2023 at 7:22:08?PM UTC-8, erik simpson wrote:
    On Wednesday, December 13, 2023 at 6:02:08?PM UTC-8, RonO wrote:
    https://pubmed.ncbi.nlm.nih.gov/37695319/

    The pdf of this article labels it as a point of view article. It is an >>>> open access article where the authors claim that the greater depth of
    the estimated phylogenetic node than an estimate based on the existing >>>> fossil record is due to an artifact of the Baysian inference of clade
    origin. It is common knowledge that molecular clock estimates of
    lineage separation is usually older than the first fossils of a new
    branching lineage.

    It sounds like it should be true if you have priors that include the
    oldest known fossils, but I really do not know if the people looking at >>>> the Cambrian diversification of bilateral animals do that. I haven't
    looked into it for decades, but they used to calibrate the clock using >>>> related lineages that had a better fossil record that was dated more
    accurately. You didn't use the nodes that you were trying to estimate, >>>> but Baysian methods do, do a reiteration from some original estimate.

    Ron Okimoto
    Bilaterian divergence took place deep in the Ediacaran, but the record is >>
    pretty sparse. As you say, the best molecular clock estimates should be
    older unless you happened to find a fossil immediately after the divergence.
    After looking some detail at Budd & Mann's paper, I notice that the putative
    discovery of Ediacaran tunicates (https://doi.org/10.1007/s12542-021-00596-1)
    isn't mentioned. If it is indeed a tunicate, it would indicate the presence of chordates
    557 Mya.


    It is what happened with the Human estimate. We knew that we didn't
    have the fossils closer to the divergence between chimps and humans.
    When we obtained more fossils the divergence started to creep towards
    the older boundary. Now, it is pushing the 8 million year estimate.
    The first clock with a reasonable amount of molecular data indicated 4.5
    to 8 million years for the divergence between chimps and humans, and the
    data favored somewhere around 5 million years, but with additional
    fossils and the desire to claim them as part of our lineage there has
    been a creep to older estimates. The molecular estimate is still within
    the 4.5 to 8 million year range, but it looks like the fossils are
    indicating that it is in the older part of the range. If we used those >fossils and their dates, you would probably be right in that the age
    would extend further into the past.

    Good info; thanks to you both.

    --

    Bob C.

    "The most exciting phrase to hear in science,
    the one that heralds new discoveries, is not
    'Eureka!' but 'That's funny...'"

    - Isaac Asimov

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  • From Ernest Major@21:1/5 to RonO on Fri Dec 15 01:49:03 2023
    On 14/12/2023 01:58, RonO wrote:
    https://pubmed.ncbi.nlm.nih.gov/37695319/

    The pdf of this article labels it as a point of view article.  It is an
    open access article where the authors claim that the greater depth of
    the estimated phylogenetic node than an estimate based on the existing
    fossil record is due to an artifact of the Baysian inference of clade origin.  It is common knowledge that molecular clock estimates of
    lineage separation is usually older than the first fossils of a new
    branching lineage.

    It sounds like it should be true if you have priors that include the
    oldest known fossils, but I really do not know if the people looking at
    the Cambrian diversification of bilateral animals do that.  I haven't
    looked into it for decades, but they used to calibrate the clock using related lineages that had a better fossil record that was dated more accurately.  You didn't use the nodes that you were trying to estimate,
    but Baysian methods do, do a reiteration from some original estimate.

    Ron Okimoto


    I had wondered how Bayesian analysis avoided concluding the assumptions.
    From the above, it seems that the answer is that sometimes it doesn't.

    --
    alias Ernest Major

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