• How NOT To Think About Cells

    From MarkE@21:1/5 to All on Sun Oct 1 22:32:38 2023
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Ernest Major@21:1/5 to MarkE on Mon Oct 2 09:45:30 2023
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.


    Hadn't you noticed that the Intelligent Design movement is very keen on
    machine model of a cell? Claiming a design beyond human conception is
    not an effective route to convincing people, so they find it to be
    rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From =?UTF-8?B?w5bDtiBUaWli?=@21:1/5 to MarkE on Mon Oct 2 04:44:22 2023
    On Monday, 2 October 2023 at 08:35:55 UTC+3, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Current biotechnology understands about half of what is going on actually. That understanding is not detailed enough for to design totally new synthetic life, but is
    plentiful for to do things with positive economic impact. Global genetic engineering
    market size is in billions dollars and growing rapidly. Those visualisation might help
    people who are studying to be specialists of that market to gain knowledge. There
    are enough similarities between nano and macro world for these animations to be useful for illustrating that.

    Otherwise yes, things that work on that nano level act somewhat differently than
    clocks and bicycles. Similarly microprocessors work somewhat differently than big
    electrical circuits. It is not beyond human comprehension, just that there are differences. But for the creationist/materialist dispute the animation is probably
    useless; anyone can see something that conforms with their views; also anyone can say that whatever in it is illusion caused by it being just a "model" and/or
    "abstraction".

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From MarkE@21:1/5 to All on Mon Oct 2 15:20:35 2023
    On Monday, October 2, 2023 at 10:45:55 PM UTC+11, Öö Tiib wrote:
    On Monday, 2 October 2023 at 08:35:55 UTC+3, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Current biotechnology understands about half of what is going on actually. That
    understanding is not detailed enough for to design totally new synthetic life, but is
    plentiful for to do things with positive economic impact. Global genetic engineering
    market size is in billions dollars and growing rapidly. Those visualisation might help
    people who are studying to be specialists of that market to gain knowledge. There
    are enough similarities between nano and macro world for these animations to be
    useful for illustrating that.

    Otherwise yes, things that work on that nano level act somewhat differently than
    clocks and bicycles. Similarly microprocessors work somewhat differently than big
    electrical circuits. It is not beyond human comprehension, just that there are
    differences. But for the creationist/materialist dispute the animation is probably
    useless; anyone can see something that conforms with their views; also anyone
    can say that whatever in it is illusion caused by it being just a "model" and/or
    "abstraction".

    I've wondered - is there a logical/mathematical limit to how much we can ever understand ourselves? Intuitively, the complexity of an observer must be much greater than the complexity of an object for "full" understanding?

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From MarkE@21:1/5 to Ernest Major on Mon Oct 2 15:13:44 2023
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on machine model of a cell? Claiming a design beyond human conception is
    not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major

    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)

    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From =?UTF-8?B?w5bDtiBUaWli?=@21:1/5 to MarkE on Mon Oct 2 16:24:56 2023
    On Tuesday, 3 October 2023 at 01:25:57 UTC+3, MarkE wrote:
    On Monday, October 2, 2023 at 10:45:55 PM UTC+11, Öö Tiib wrote:
    On Monday, 2 October 2023 at 08:35:55 UTC+3, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Current biotechnology understands about half of what is going on actually. That
    understanding is not detailed enough for to design totally new synthetic life, but is
    plentiful for to do things with positive economic impact. Global genetic engineering
    market size is in billions dollars and growing rapidly. Those visualisation might help
    people who are studying to be specialists of that market to gain knowledge. There
    are enough similarities between nano and macro world for these animations to be
    useful for illustrating that.

    Otherwise yes, things that work on that nano level act somewhat differently than
    clocks and bicycles. Similarly microprocessors work somewhat differently than big
    electrical circuits. It is not beyond human comprehension, just that there are
    differences. But for the creationist/materialist dispute the animation is probably
    useless; anyone can see something that conforms with their views; also anyone
    can say that whatever in it is illusion caused by it being just a "model" and/or
    "abstraction".

    I've wondered - is there a logical/mathematical limit to how much we can ever understand ourselves? Intuitively, the complexity of an observer must be much greater than the complexity of an object for "full" understanding?


    In my experience there are no limits as there are no need for anyone of us to understand anything fully. We are not doomed to work alone, so there are no point. For example Google Chrome web browser contains about 35 millions of lines of program code. If a hypothetical very bright programmer could read and understand it at speed of 35 lines per minute then it would still take about 9 years to go through all of it for him. No one does that and so everybody working
    on the code base have full understanding of only some parts of it.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From brogers31751@gmail.com@21:1/5 to MarkE on Mon Oct 2 17:00:28 2023
    On Monday, October 2, 2023 at 6:15:56 PM UTC-4, MarkE wrote:
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on machine model of a cell? Claiming a design beyond human conception is
    not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major
    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)

    You can certainly define "machine" in such a way that the flagellum or the ribosome "*is* a machine!" That tells you nothing new about flagella or ribosomes, only about how you've decided to use words.

    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From MarkE@21:1/5 to broger...@gmail.com on Mon Oct 2 18:03:54 2023
    On Tuesday, October 3, 2023 at 11:00:56 AM UTC+11, broger...@gmail.com wrote:
    On Monday, October 2, 2023 at 6:15:56 PM UTC-4, MarkE wrote:
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on machine model of a cell? Claiming a design beyond human conception is not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major
    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)
    You can certainly define "machine" in such a way that the flagellum or the ribosome "*is* a machine!" That tells you nothing new about flagella or ribosomes, only about how you've decided to use words.

    Sure, it's definitions and semantics. But would you agree that the following object might qualify as a "machine" by some definitions?

    "The prokaryotic flagellum spins, driven by a rotary motor at speeds of over 100,000 rpm in at least one species. The torque generated by the motor is converted to thrust by the corkscrew-shaped filament or propeller."

    "Bacterial Flagellum: Visualizing the Complete Machine In Situ" https://www.sciencedirect.com/science/article/pii/S096098220602286X


    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From MarkE@21:1/5 to MarkE on Mon Oct 2 18:19:47 2023
    On Tuesday, October 3, 2023 at 12:05:56 PM UTC+11, MarkE wrote:
    On Tuesday, October 3, 2023 at 11:00:56 AM UTC+11, broger...@gmail.com wrote:
    On Monday, October 2, 2023 at 6:15:56 PM UTC-4, MarkE wrote:
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on
    machine model of a cell? Claiming a design beyond human conception is not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major
    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)
    You can certainly define "machine" in such a way that the flagellum or the ribosome "*is* a machine!" That tells you nothing new about flagella or ribosomes, only about how you've decided to use words.
    Sure, it's definitions and semantics. But would you agree that the following object might qualify as a "machine" by some definitions?

    "The prokaryotic flagellum spins, driven by a rotary motor at speeds of over 100,000 rpm in at least one species. The torque generated by the motor is converted to thrust by the corkscrew-shaped filament or propeller."

    "Bacterial Flagellum: Visualizing the Complete Machine In Situ" https://www.sciencedirect.com/science/article/pii/S096098220602286X

    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.

    That is, '...qualify as a "machine" by some widely accepted definitions?'

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From MarkE@21:1/5 to All on Mon Oct 2 18:16:04 2023
    On Tuesday, October 3, 2023 at 10:25:56 AM UTC+11, Öö Tiib wrote:
    On Tuesday, 3 October 2023 at 01:25:57 UTC+3, MarkE wrote:
    On Monday, October 2, 2023 at 10:45:55 PM UTC+11, Öö Tiib wrote:
    On Monday, 2 October 2023 at 08:35:55 UTC+3, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Current biotechnology understands about half of what is going on actually. That
    understanding is not detailed enough for to design totally new synthetic life, but is
    plentiful for to do things with positive economic impact. Global genetic engineering
    market size is in billions dollars and growing rapidly. Those visualisation might help
    people who are studying to be specialists of that market to gain knowledge. There
    are enough similarities between nano and macro world for these animations to be
    useful for illustrating that.

    Otherwise yes, things that work on that nano level act somewhat differently than
    clocks and bicycles. Similarly microprocessors work somewhat differently than big
    electrical circuits. It is not beyond human comprehension, just that there are
    differences. But for the creationist/materialist dispute the animation is probably
    useless; anyone can see something that conforms with their views; also anyone
    can say that whatever in it is illusion caused by it being just a "model" and/or
    "abstraction".

    I've wondered - is there a logical/mathematical limit to how much we can ever understand ourselves? Intuitively, the complexity of an observer must be much greater than the complexity of an object for "full" understanding?

    In my experience there are no limits as there are no need for anyone of us to
    understand anything fully. We are not doomed to work alone, so there are no point. For example Google Chrome web browser contains about 35 millions of lines of program code. If a hypothetical very bright programmer could read and
    understand it at speed of 35 lines per minute then it would still take about 9
    years to go through all of it for him. No one does that and so everybody working
    on the code base have full understanding of only some parts of it.

    You raise an interesting point. The accumulated collective human knowledge on say humans vastly exceeds an individual's capacity to even read it, let alone "understand" it. Is it still possible to claim "full" collective human understanding if by
    definition this knowledge can never be integrated and assessed holistically?

    Moreover, regardless, is the number of human minds applied to understanding the human mind irrelevant, i.e. is there a circularity here that logically prevents this?

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From =?UTF-8?B?w5bDtiBUaWli?=@21:1/5 to MarkE on Mon Oct 2 23:13:10 2023
    On Tuesday, 3 October 2023 at 04:20:56 UTC+3, MarkE wrote:
    On Tuesday, October 3, 2023 at 10:25:56 AM UTC+11, Öö Tiib wrote:
    On Tuesday, 3 October 2023 at 01:25:57 UTC+3, MarkE wrote:
    On Monday, October 2, 2023 at 10:45:55 PM UTC+11, Öö Tiib wrote:
    On Monday, 2 October 2023 at 08:35:55 UTC+3, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Current biotechnology understands about half of what is going on actually. That
    understanding is not detailed enough for to design totally new synthetic life, but is
    plentiful for to do things with positive economic impact. Global genetic engineering
    market size is in billions dollars and growing rapidly. Those visualisation might help
    people who are studying to be specialists of that market to gain knowledge. There
    are enough similarities between nano and macro world for these animations to be
    useful for illustrating that.

    Otherwise yes, things that work on that nano level act somewhat differently than
    clocks and bicycles. Similarly microprocessors work somewhat differently than big
    electrical circuits. It is not beyond human comprehension, just that there are
    differences. But for the creationist/materialist dispute the animation is probably
    useless; anyone can see something that conforms with their views; also anyone
    can say that whatever in it is illusion caused by it being just a "model" and/or
    "abstraction".

    I've wondered - is there a logical/mathematical limit to how much we can ever understand ourselves? Intuitively, the complexity of an observer must be much greater than the complexity of an object for "full" understanding?

    In my experience there are no limits as there are no need for anyone of us to
    understand anything fully. We are not doomed to work alone, so there are no
    point. For example Google Chrome web browser contains about 35 millions of lines of program code. If a hypothetical very bright programmer could read and
    understand it at speed of 35 lines per minute then it would still take about 9
    years to go through all of it for him. No one does that and so everybody working
    on the code base have full understanding of only some parts of it.

    You raise an interesting point. The accumulated collective human knowledge on say humans vastly exceeds an individual's capacity to even read it, let alone "understand" it. Is it still possible to claim "full" collective human understanding if by
    definition this knowledge can never be integrated and assessed holistically?

    One does not need deep understanding of something for to use and integrate
    it. Kid needs to know Pythagorean theorem for to use it to solve some geometrical problem. Full knowledge why it is so and how to prove the
    theorem is not needed. More details can be learned when needed.

    Moreover, regardless, is the number of human minds applied to understanding the human mind irrelevant, i.e. is there a circularity here that logically prevents this?

    Seems there are no problems. We are already in process of making and
    improving artificial minds as collective without anyone having full understanding how minds work. Individual specialist may have good
    knowledge of some detail like analyzing time series or pattern matching or such, but no one has individual full knowledge of everything.

    Or how that synthetic genome was composed by 2016 in Craig Venter
    laboratory without anyone knowing function of 149 genes from total 473.
    It is possible to use things not only without fully understanding those but without understanding those at all. They knew function of 324 genes so rest will be also perhaps figured out with time.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From brogers31751@gmail.com@21:1/5 to MarkE on Tue Oct 3 03:03:21 2023
    On Monday, October 2, 2023 at 9:20:56 PM UTC-4, MarkE wrote:
    On Tuesday, October 3, 2023 at 12:05:56 PM UTC+11, MarkE wrote:
    On Tuesday, October 3, 2023 at 11:00:56 AM UTC+11, broger...@gmail.com wrote:
    On Monday, October 2, 2023 at 6:15:56 PM UTC-4, MarkE wrote:
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on
    machine model of a cell? Claiming a design beyond human conception is
    not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major
    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)
    You can certainly define "machine" in such a way that the flagellum or the ribosome "*is* a machine!" That tells you nothing new about flagella or ribosomes, only about how you've decided to use words.
    Sure, it's definitions and semantics. But would you agree that the following object might qualify as a "machine" by some definitions?

    "The prokaryotic flagellum spins, driven by a rotary motor at speeds of over 100,000 rpm in at least one species. The torque generated by the motor is converted to thrust by the corkscrew-shaped filament or propeller."

    "Bacterial Flagellum: Visualizing the Complete Machine In Situ" https://www.sciencedirect.com/science/article/pii/S096098220602286X

    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.
    That is, '...qualify as a "machine" by some widely accepted definitions?'
    Sure, why not? Just so long as you are careful not to attribute characteristics to the bacterial flagellum inherited from other definitions of "machine" which include characteristics like "artificial" or "man-made" and imply a designer.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Mark Isaak@21:1/5 to MarkE on Tue Oct 3 07:23:50 2023
    On 10/1/23 10:32 PM, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    I'm reminded of a comment near the beginning of _The Extended Mind_
    (which I am very much enjoying; thanks to whomever mentioned it here
    earlier): When computers were first invented, they were compared to
    brains. Later, the metaphor switched, and brains came to be compared to computers. Before that, they were compared with switchboards; before
    that, no doubt to something else. Metaphors shift according to
    available technology.

    Cells are not machines. They are cells.

    --
    Mark Isaak
    "Wisdom begins when you discover the difference between 'That
    doesn't make sense' and 'I don't understand.'" - Mary Doria Russell

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Glenn@21:1/5 to Ernest Major on Tue Oct 3 13:07:40 2023
    On Monday, October 2, 2023 at 1:45:55 AM UTC-7, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on machine model of a cell? Claiming a design beyond human conception is
    not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    You really think you are on the side of science, don't you.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Glenn@21:1/5 to MarkE on Tue Oct 3 13:10:32 2023
    On Monday, October 2, 2023 at 6:05:56 PM UTC-7, MarkE wrote:
    On Tuesday, October 3, 2023 at 11:00:56 AM UTC+11, broger...@gmail.com wrote:
    On Monday, October 2, 2023 at 6:15:56 PM UTC-4, MarkE wrote:
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on
    machine model of a cell? Claiming a design beyond human conception is not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major
    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)
    You can certainly define "machine" in such a way that the flagellum or the ribosome "*is* a machine!" That tells you nothing new about flagella or ribosomes, only about how you've decided to use words.
    Sure, it's definitions and semantics. But would you agree that the following object might qualify as a "machine" by some definitions?

    "The prokaryotic flagellum spins, driven by a rotary motor at speeds of over 100,000 rpm in at least one species. The torque generated by the motor is converted to thrust by the corkscrew-shaped filament or propeller."

    "Bacterial Flagellum: Visualizing the Complete Machine In Situ" https://www.sciencedirect.com/science/article/pii/S096098220602286X

    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.

    Mark, you may be interested in Michael Levin's work. Look him up on youtube.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From MarkE@21:1/5 to Glenn on Tue Oct 3 17:55:16 2023
    On Wednesday, October 4, 2023 at 7:15:57 AM UTC+11, Glenn wrote:
    On Monday, October 2, 2023 at 6:05:56 PM UTC-7, MarkE wrote:
    On Tuesday, October 3, 2023 at 11:00:56 AM UTC+11, broger...@gmail.com wrote:
    On Monday, October 2, 2023 at 6:15:56 PM UTC-4, MarkE wrote:
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on
    machine model of a cell? Claiming a design beyond human conception is
    not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major
    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)
    You can certainly define "machine" in such a way that the flagellum or the ribosome "*is* a machine!" That tells you nothing new about flagella or ribosomes, only about how you've decided to use words.
    Sure, it's definitions and semantics. But would you agree that the following object might qualify as a "machine" by some definitions?

    "The prokaryotic flagellum spins, driven by a rotary motor at speeds of over 100,000 rpm in at least one species. The torque generated by the motor is converted to thrust by the corkscrew-shaped filament or propeller."

    "Bacterial Flagellum: Visualizing the Complete Machine In Situ" https://www.sciencedirect.com/science/article/pii/S096098220602286X

    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.
    Mark, you may be interested in Michael Levin's work. Look him up on youtube.

    Thanks - I have seen him talk about bioelectricity.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From MarkE@21:1/5 to Mark Isaak on Tue Oct 3 18:07:35 2023
    On Wednesday, October 4, 2023 at 1:25:57 AM UTC+11, Mark Isaak wrote:
    On 10/1/23 10:32 PM, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.
    I'm reminded of a comment near the beginning of _The Extended Mind_
    (which I am very much enjoying; thanks to whomever mentioned it here earlier): When computers were first invented, they were compared to
    brains. Later, the metaphor switched, and brains came to be compared to computers. Before that, they were compared with switchboards; before
    that, no doubt to something else. Metaphors shift according to
    available technology.

    Cells are not machines. They are cells.


    Don't be afraid of metaphors:

    "In science, metaphors have proved to be very useful because they facilitate analogical reasoning, the process whereby scientists transfer what they understand about one subject or phenomenon to another seemingly disparate and less familiar one. This
    sometimes leads to the discovery or expansion of a more general pattern, phenomenon, mechanism or law. Metaphors and analogies might therefore be called the engines of scientific advancement."

    How about "factory" as a metaphor for the cell?

    "Examples like ‘the cell is a factory’ demonstrate that sometimes a metaphor can become literal not because it changes the way we use language, but because it changes the very nature of the thing being described metaphorically. The metaphorical
    description of the cell as a factory became literal when scientists genetically engineered bacteria to express the gene for human insulin (among others), turning these cells into literal factories for the production of valuable commodities. This was a
    hugely beneficial development for people with diabetes, but it illustrates another reason why metaphors must be used cautiously: they may end up changing not just the way we speak, but our environments, our societies and ourselves in very tangible ways. (
    Which version of the human genome will our descendants be running – H. sapiens 2.0?)"

    https://www.rsb.org.uk/biologist-features/master-your-metaphors

    --
    Mark Isaak
    "Wisdom begins when you discover the difference between 'That
    doesn't make sense' and 'I don't understand.'" - Mary Doria Russell

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From brogers31751@gmail.com@21:1/5 to MarkE on Wed Oct 4 03:45:34 2023
    On Tuesday, October 3, 2023 at 9:10:57 PM UTC-4, MarkE wrote:
    On Wednesday, October 4, 2023 at 1:25:57 AM UTC+11, Mark Isaak wrote:
    On 10/1/23 10:32 PM, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.
    I'm reminded of a comment near the beginning of _The Extended Mind_
    (which I am very much enjoying; thanks to whomever mentioned it here earlier): When computers were first invented, they were compared to brains. Later, the metaphor switched, and brains came to be compared to computers. Before that, they were compared with switchboards; before
    that, no doubt to something else. Metaphors shift according to
    available technology.

    Cells are not machines. They are cells.

    Don't be afraid of metaphors:

    "In science, metaphors have proved to be very useful because they facilitate analogical reasoning, the process whereby scientists transfer what they understand about one subject or phenomenon to another seemingly disparate and less familiar one. This
    sometimes leads to the discovery or expansion of a more general pattern, phenomenon, mechanism or law. Metaphors and analogies might therefore be called the engines of scientific advancement."

    How about "factory" as a metaphor for the cell?

    "Examples like ‘the cell is a factory’ demonstrate that sometimes a metaphor can become literal not because it changes the way we use language, but because it changes the very nature of the thing being described metaphorically. The metaphorical
    description of the cell as a factory became literal when scientists genetically engineered bacteria to express the gene for human insulin (among others), turning these cells into literal factories for the production of valuable commodities. This was a
    hugely beneficial development for people with diabetes, but it illustrates another reason why metaphors must be used cautiously: they may end up changing not just the way we speak, but our environments, our societies and ourselves in very tangible ways. (
    Which version of the human genome will our descendants be running – H. sapiens 2.0?)"

    https://www.rsb.org.uk/biologist-features/master-your-metaphors

    Yes, metaphors or analogies can be very useful for generating ideas. They don't, by themselves, though, tell you anything at all. If you say "the bacterial flagellum is analogous to an outboard motor, it must have some kind of fuel," then you have to do
    a bunch of experiments to show how the energy released by hydrolysis of ATP is coupled to motion of the flagellum. Saying "there must be some kind of fuel but we are not going to investigate what the fuel is, how it works or where it is produced" won't
    cut it.
    --
    Mark Isaak
    "Wisdom begins when you discover the difference between 'That
    doesn't make sense' and 'I don't understand.'" - Mary Doria Russell

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From jillery@21:1/5 to All on Wed Oct 4 11:02:31 2023
    On Tue, 3 Oct 2023 18:07:35 -0700 (PDT), MarkE <me22over7@gmail.com>
    wrote:

    On Wednesday, October 4, 2023 at 1:25:57?AM UTC+11, Mark Isaak wrote:
    On 10/1/23 10:32 PM, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.
    I'm reminded of a comment near the beginning of _The Extended Mind_
    (which I am very much enjoying; thanks to whomever mentioned it here
    earlier): When computers were first invented, they were compared to
    brains. Later, the metaphor switched, and brains came to be compared to
    computers. Before that, they were compared with switchboards; before
    that, no doubt to something else. Metaphors shift according to
    available technology.

    Cells are not machines. They are cells.


    Don't be afraid of metaphors:

    "In science, metaphors have proved to be very useful because they facilitate analogical reasoning, the process whereby scientists transfer what they understand about one subject or phenomenon to another seemingly disparate and less familiar one. This
    sometimes leads to the discovery or expansion of a more general pattern, phenomenon, mechanism or law. Metaphors and analogies might therefore be called the engines of scientific advancement."

    How about "factory" as a metaphor for the cell?

    "Examples like ‘the cell is a factory’ demonstrate that sometimes a metaphor can become literal not because it changes the way we use language, but because it changes the very nature of the thing being described metaphorically. The metaphorical
    description of the cell as a factory became literal when scientists genetically engineered bacteria to express the gene for human insulin (among others), turning these cells into literal factories for the production of valuable commodities. This was a
    hugely beneficial development for people with diabetes, but it illustrates another reason why metaphors must be used cautiously: they may end up changing not just the way we speak, but our environments, our societies and ourselves in very tangible ways. (
    Which version of the human genome will our descendants be running – H. sapiens 2.0?)"

    https://www.rsb.org.uk/biologist-features/master-your-metaphors


    Metaphors illustrate and describe. The danger to using metaphors is
    to base conclusions which go beyond their scope. For example, the Sun
    has been metaphorically thought of as a lump of coal, because it too
    gives off light and heat, but we have known for a long time that its
    source of energy is very different.

    --
    To know less than we don't know is the nature of most knowledge

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Glenn@21:1/5 to broger...@gmail.com on Wed Oct 4 11:27:35 2023
    On Wednesday, October 4, 2023 at 3:45:58 AM UTC-7, broger...@gmail.com wrote:
    On Tuesday, October 3, 2023 at 9:10:57 PM UTC-4, MarkE wrote:
    On Wednesday, October 4, 2023 at 1:25:57 AM UTC+11, Mark Isaak wrote:
    On 10/1/23 10:32 PM, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.
    I'm reminded of a comment near the beginning of _The Extended Mind_ (which I am very much enjoying; thanks to whomever mentioned it here earlier): When computers were first invented, they were compared to brains. Later, the metaphor switched, and brains came to be compared to computers. Before that, they were compared with switchboards; before that, no doubt to something else. Metaphors shift according to
    available technology.

    Cells are not machines. They are cells.

    Don't be afraid of metaphors:

    "In science, metaphors have proved to be very useful because they facilitate analogical reasoning, the process whereby scientists transfer what they understand about one subject or phenomenon to another seemingly disparate and less familiar one. This
    sometimes leads to the discovery or expansion of a more general pattern, phenomenon, mechanism or law. Metaphors and analogies might therefore be called the engines of scientific advancement."

    How about "factory" as a metaphor for the cell?

    "Examples like ‘the cell is a factory’ demonstrate that sometimes a metaphor can become literal not because it changes the way we use language, but because it changes the very nature of the thing being described metaphorically. The metaphorical
    description of the cell as a factory became literal when scientists genetically engineered bacteria to express the gene for human insulin (among others), turning these cells into literal factories for the production of valuable commodities. This was a
    hugely beneficial development for people with diabetes, but it illustrates another reason why metaphors must be used cautiously: they may end up changing not just the way we speak, but our environments, our societies and ourselves in very tangible ways. (
    Which version of the human genome will our descendants be running – H. sapiens 2.0?)"

    https://www.rsb.org.uk/biologist-features/master-your-metaphors
    Yes, metaphors or analogies can be very useful for generating ideas. They don't, by themselves, though, tell you anything at all. If you say "the bacterial flagellum is analogous to an outboard motor, it must have some kind of fuel," then you have to
    do a bunch of experiments to show how the energy released by hydrolysis of ATP is coupled to motion of the flagellum. Saying "there must be some kind of fuel but we are not going to investigate what the fuel is, how it works or where it is produced" won'
    t cut it.
    --
    Saying random mutations all added up to produce such complicated systems is what won't cut it. Stick that in your metaphor and smoke it.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Glenn@21:1/5 to MarkE on Wed Oct 4 11:25:22 2023
    On Tuesday, October 3, 2023 at 5:55:57 PM UTC-7, MarkE wrote:
    On Wednesday, October 4, 2023 at 7:15:57 AM UTC+11, Glenn wrote:
    On Monday, October 2, 2023 at 6:05:56 PM UTC-7, MarkE wrote:
    On Tuesday, October 3, 2023 at 11:00:56 AM UTC+11, broger...@gmail.com wrote:
    On Monday, October 2, 2023 at 6:15:56 PM UTC-4, MarkE wrote:
    On Monday, October 2, 2023 at 7:45:55 PM UTC+11, Ernest Major wrote:
    On 02/10/2023 06:32, MarkE wrote:
    "A few years ago Veritasium posted a video portraying 'molecular machines'. But is that really the right way to think about the inner workings of our cells? Are we all just running on molecular clockwork?"

    https://youtu.be/jPhvic-eqbc?si=_AaJLOYY5FPiZ8aK

    I thought this was worth sharing (the presenter assumes evolution; not a creationist video). He challenges the machine metaphor for cells and the electronic circuit for enzyme function.

    I guess evolution will claim this as the messy and jerry-built product of trial and error, and ID will claim it as adaptable multifunctional design beyond human conception.

    Either way, enjoy, and consider that our understanding of the cell may be far less that we realise.

    Hadn't you noticed that the Intelligent Design movement is very keen on
    machine model of a cell? Claiming a design beyond human conception is
    not an effective route to convincing people, so they find it to be rhetorically advantageous to play up similarities to mechanical devices.

    --
    alias Ernest Major
    Both evolution and ID predict "a design beyond human conception" - hence the inherent conflict.

    As much as I appreciate the reframe of the video, the flagellum, for example, *is* a machine! Along with kinesin, ribosome, spliceosome, etc, etc... If it walks like machine and quacks like a machine, it probably is a mechanical duck :)
    You can certainly define "machine" in such a way that the flagellum or the ribosome "*is* a machine!" That tells you nothing new about flagella or ribosomes, only about how you've decided to use words.
    Sure, it's definitions and semantics. But would you agree that the following object might qualify as a "machine" by some definitions?

    "The prokaryotic flagellum spins, driven by a rotary motor at speeds of over 100,000 rpm in at least one species. The torque generated by the motor is converted to thrust by the corkscrew-shaped filament or propeller."

    "Bacterial Flagellum: Visualizing the Complete Machine In Situ" https://www.sciencedirect.com/science/article/pii/S096098220602286X

    And the cell in total? The "factory" or "city" metaphor seems like a reasonable starting point - apparent chaos resulting in order and output.
    Mark, you may be interested in Michael Levin's work. Look him up on youtube.
    Thanks - I have seen him talk about bioelectricity.

    He's an interesting individual. His regard for evolution is unclear, though he has made statements that appear to be possibly ways to avoid the ire of evolutionists. The purpose of his research is claimed to be for practical engineering applications, and
    I have found nothing in his philosophy that would support an insistence of materialistic, unguided, random evolution. What he seems to have discovered so far though should be quite shocking to atheist evolutionists, and possibly as well as to some IDers.
    Hopefully he can keep the money flowing and not get booted for what he might find in the future.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)