https://www.science.org/doi/10.1126/science.adf8009
This study published in science looked at skeletal differences within a >portion of the UK human biobank that has skeletal bone measurements.
They did a GWAS (genome wide association study) to identify genes
associated with skeletal differences and looked into what these genes do
and what phenotypes and diseases they have been associated with. This >confirmed the association with bone morphology.
They also did an evolutionary analysis because humans have a lot of
skeletal changes compared to our primate ancestors. They looked at HAR >genomic sequences (regions of the genome that show accelerated change >compared our evolutionary relatives, and associated genes with things
like our leg length and arm length change in ratio compared to apes and >other skeletal changes like our hip morphology.
There will likely be Science news articles on the research. They seem
to have found some of the genes that had to change to make us humans, at >least, in the morphological sense of what we look like.
Ron Okimoto
On Sun, 23 Jul 2023 08:12:06 -0500, RonO <rokimoto@cox.net> wrote:
https://www.science.org/doi/10.1126/science.adf8009
This study published in science looked at skeletal differences within a
portion of the UK human biobank that has skeletal bone measurements.
They did a GWAS (genome wide association study) to identify genes
associated with skeletal differences and looked into what these genes do
and what phenotypes and diseases they have been associated with. This
confirmed the association with bone morphology.
They also did an evolutionary analysis because humans have a lot of
skeletal changes compared to our primate ancestors. They looked at HAR
genomic sequences (regions of the genome that show accelerated change
compared our evolutionary relatives, and associated genes with things
like our leg length and arm length change in ratio compared to apes and
other skeletal changes like our hip morphology.
There will likely be Science news articles on the research. They seem
to have found some of the genes that had to change to make us humans, at
least, in the morphological sense of what we look like.
Ron Okimoto
What is "HAR"?
On 7/23/2023 9:07 AM, jillery wrote:
On Sun, 23 Jul 2023 08:12:06 -0500, RonO <rokimoto@cox.net> wrote:
https://www.science.org/doi/10.1126/science.adf8009
This study published in science looked at skeletal differences within a
portion of the UK human biobank that has skeletal bone measurements.
They did a GWAS (genome wide association study) to identify genes
associated with skeletal differences and looked into what these genes do >>> and what phenotypes and diseases they have been associated with. This
confirmed the association with bone morphology.
They also did an evolutionary analysis because humans have a lot of
skeletal changes compared to our primate ancestors. They looked at HAR
genomic sequences (regions of the genome that show accelerated change
compared our evolutionary relatives, and associated genes with things
like our leg length and arm length change in ratio compared to apes and
other skeletal changes like our hip morphology.
There will likely be Science news articles on the research. They seem
to have found some of the genes that had to change to make us humans, at >>> least, in the morphological sense of what we look like.
Ron Okimoto
What is "HAR"?
I think that I defined it. It looks like I did not close the
parenthetical phrase. HAR means human accelerated regions of the genome.
These are genomic sequence that have had a faster rate of change than
the same sequences in other great apes.
Ron Okimoto
https://www.science.org/doi/10.1126/science.adf8009
This study published in science looked at skeletal differences within a portion of the UK human biobank that has skeletal bone measurements.
They did a GWAS (genome wide association study) to identify genes
associated with skeletal differences and looked into what these genes do
and what phenotypes and diseases they have been associated with. This confirmed the association with bone morphology.
They also did an evolutionary analysis because humans have a lot of
skeletal changes compared to our primate ancestors. They looked at HAR genomic sequences (regions of the genome that show accelerated change compared our evolutionary relatives, and associated genes with things
like our leg length and arm length change in ratio compared to apes and
other skeletal changes like our hip morphology.
There will likely be Science news articles on the research. They seem
to have found some of the genes that had to change to make us humans, at least, in the morphological sense of what we look like.
Ron Okimoto
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