• marionetes

    From Lawyer Daggett@21:1/5 to All on Thu Apr 27 12:38:30 2023
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From jillery@21:1/5 to j.nobel.daggett@gmail.com on Thu Apr 27 21:35:46 2023
    On Thu, 27 Apr 2023 12:38:30 -0700 (PDT), Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:

    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.


    Seriously, pause and ask yourself if your contribution is helping.
    Almost always, you blame those who note willful stupidity while
    completely ignoring that willful stupidity.

    --
    You're entitled to your own opinions.
    You're not entitled to your own facts.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From jillery@21:1/5 to j.nobel.daggett@gmail.com on Thu Apr 27 23:38:37 2023
    On Thu, 27 Apr 2023 12:38:30 -0700 (PDT), Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:

    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.


    Even IF your negative description of my "retorts" was objectively
    accurate, the valid measure is against the posts to which they retort,
    and not to those presumptively brilliant and insightful pearls of
    wisdom you would have posted if only you had managed to scrape a
    fraction of energy for them as you and others do to post mindless
    made-up crap against me, which serves to give aid and comfort to those
    whom I retort. Seriously, pause and consider how YOUR contributions,
    and their lack, affect this froup.

    --
    You're entitled to your own opinions.
    You're not entitled to your own facts.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Mark Isaak@21:1/5 to jillery on Fri Apr 28 07:24:04 2023
    On 4/27/23 8:38 PM, jillery wrote:
    On Thu, 27 Apr 2023 12:38:30 -0700 (PDT), Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:

    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.


    Even IF your negative description of my "retorts" was objectively
    accurate, the valid measure is against the posts to which they retort,
    and not to those presumptively brilliant and insightful pearls of
    wisdom you would have posted if only you had managed to scrape a
    fraction of energy for them as you and others do to post mindless
    made-up crap against me, which serves to give aid and comfort to those
    whom I retort. Seriously, pause and consider how YOUR contributions,
    and their lack, affect this froup.

    Since you brought it up, I have found that Lawyer Daggett always has
    something thoughtful to say when he posts, so I look forward to reading
    his posts. In contrast, I skip over the vast majority of your posts,
    for reasons which should be obvious.

    --
    Mark Isaak
    "Wisdom begins when you discover the difference between 'That
    doesn't make sense' and 'I don't understand.'" - Mary Doria Russell

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From jillery@21:1/5 to specimenNOSPAM@curioustaxon.omy.net on Fri Apr 28 13:12:50 2023
    On Fri, 28 Apr 2023 07:24:04 -0700, Mark Isaak <specimenNOSPAM@curioustaxon.omy.net> wrote:

    On 4/27/23 8:38 PM, jillery wrote:
    On Thu, 27 Apr 2023 12:38:30 -0700 (PDT), Lawyer Daggett
    <j.nobel.daggett@gmail.com> wrote:

    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.


    Even IF your negative description of my "retorts" was objectively
    accurate, the valid measure is against the posts to which they retort,
    and not to those presumptively brilliant and insightful pearls of
    wisdom you would have posted if only you had managed to scrape a
    fraction of energy for them as you and others do to post mindless
    made-up crap against me, which serves to give aid and comfort to those
    whom I retort. Seriously, pause and consider how YOUR contributions,
    and their lack, affect this froup.

    Since you brought it up, I have found that Lawyer Daggett always has >something thoughtful to say when he posts, so I look forward to reading
    his posts. In contrast, I skip over the vast majority of your posts,
    for reasons which should be obvious.


    There's that word again. It's such an easy way to pretend to have said something thoughtful.

    What you choose to read, or not, and to whom you choose to reply, or
    not, is entirely up to you. That you choose to not read my posts
    makes you willfully stupid about your replies to me. And that's also
    entirely up to you.

    --
    You're entitled to your own opinions.
    You're not entitled to your own facts.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From *Hemidactylus*@21:1/5 to Lawyer Daggett on Sat Apr 29 00:46:27 2023
    Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided vision I’ve had ever but with some minor flare and ghosting. Looking
    forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s book. Too much junk in the trunk.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From erik simpson@21:1/5 to All on Fri Apr 28 19:15:24 2023
    On Friday, April 28, 2023 at 5:50:05 PM UTC-7, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my perspective. Not as much single eye halos and multivision. Best non-aided vision I’ve had ever but with some minor flare and ghosting. Looking forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.
    Just wait, it gets better. Your brain will take care of the flare and ghosting all by
    itself. Not AI, this is Natural Intelligence. It's still there, of course, you just won't be
    aware of it.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Lawyer Daggett@21:1/5 to erik simpson on Fri Apr 28 19:33:47 2023
    On Friday, April 28, 2023 at 10:20:05 PM UTC-4, erik simpson wrote:
    On Friday, April 28, 2023 at 5:50:05 PM UTC-7, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my perspective. Not as much single eye halos and multivision. Best non-aided vision I’ve had ever but with some minor flare and ghosting. Looking forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.
    Just wait, it gets better. Your brain will take care of the flare and ghosting all by
    itself. Not AI, this is Natural Intelligence. It's still there, of course, you just won't be
    aware of it.

    And you can watch like there's nobody dancing.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From *Hemidactylus*@21:1/5 to erik simpson on Sat Apr 29 03:10:08 2023
    erik simpson <eastside.erik@gmail.com> wrote:
    On Friday, April 28, 2023 at 5:50:05 PM UTC-7, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided
    vision I’ve had ever but with some minor flare and ghosting. Looking
    forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.
    Just wait, it gets better. Your brain will take care of the flare and ghosting all by
    itself. Not AI, this is Natural Intelligence. It's still there, of
    course, you just won't be
    aware of it.

    Yeah the neuroadaptation is supposed to take care of that. I got a Vivity extended depth instead of monofocal. Reading vision isn’t bad. I knew going in there were trade-offs. I avoided the multifocal because fear of night
    vision anomalies. Night vision is pretty good now. With cataract I had
    rainbow halos. Now a little weird on lights but I had starbursts 20 years
    ago before the cataract. Was thinking of doing a more close vision
    monovision with a EDOF in left eye but now leaning toward same lens and
    getting readers if needed. Was tempted to go multifocal next or monofocal
    but I’m fine with the extended depth for driving and computer screen.

    I’m worried about longterm with the prescribed steroid drops. Before
    cataract diagnosis I worried about keratoconus. Steroids can fuck up a
    cornea.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Lawyer Daggett@21:1/5 to All on Fri Apr 28 19:38:29 2023
    On Friday, April 28, 2023 at 8:50:05 PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my perspective. Not as much single eye halos and multivision. Best non-aided vision I’ve had ever but with some minor flare and ghosting. Looking forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life.
    When it comes to our genomes, we humans are nothing special – Moran
    makes a convincing argument that the vast majority of our sloppy human
    genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced
    that most of the sequence in our genomes is intricately functional, that
    the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with
    this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’
    and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science, Boston University

    "A serious warning to scientists and science writers who, to seduce their public, privilege the too-fast announcement of novelties and revolutions instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on
    what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History
    and Philosophy of Sciences and Techniques , Université Paris 1 Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling truth – the DNA sequences that specify our body’s proteins and RNAs are indeed finely honed by natural selection (like a Swiss watch), but they are only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them
    into the weeds of confusion the way that Dr. Moran does, but the rewards
    are there to be reaped. A thorough reader will never look at the genome of
    any living organism or the concept of junk DNA the same way after reading
    this and will be left wondering how so many baseless claims have made headlines in recent years. In the capable hands of Dr. Moran, we can all
    learn to untangle facts from unsupported assertions and come away understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists, yet arguments about its existence are commonplace. In What’s in Your Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA
    is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From John Harshman@21:1/5 to Lawyer Daggett on Sat Apr 29 06:32:12 2023
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05 PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided
    vision I’ve had ever but with some minor flare and ghosting. Looking
    forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life.
    When it comes to our genomes, we humans are nothing special – Moran
    makes a convincing argument that the vast majority of our sloppy human
    genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced
    that most of the sequence in our genomes is intricately functional, that
    the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with
    this. Laurence A. Moran's clear and incisive book explains why many biologists are so thoroughly mistaken – why our genomes are ‘messy,’ and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science, Boston University

    "A serious warning to scientists and science writers who, to seduce their public, privilege the too-fast announcement of novelties and revolutions instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on
    what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History
    and Philosophy of Sciences and Techniques , Université Paris 1 Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling truth – the DNA sequences that specify our body’s proteins and RNAs are indeed finely honed by natural selection (like a Swiss watch), but they are only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them into the weeds of confusion the way that Dr. Moran does, but the rewards
    are there to be reaped. A thorough reader will never look at the genome of any living organism or the concept of junk DNA the same way after reading this and will be left wondering how so many baseless claims have made headlines in recent years. In the capable hands of Dr. Moran, we can all learn to untangle facts from unsupported assertions and come away understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists, yet arguments about its existence are commonplace. In What’s in Your Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA
    is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member
    of the ENCODE project, everyone who's ever claimed that all non-codimg
    DNA was originally thought to be junk DNA, and in general any biologist
    who's ever said that junk was dead as a concept.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Lawyer Daggett@21:1/5 to John Harshman on Sat Apr 29 06:59:17 2023
    On Saturday, April 29, 2023 at 9:35:05 AM UTC-4, John Harshman wrote:
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05 PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided >> vision I’ve had ever but with some minor flare and ghosting. Looking
    forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life. When it comes to our genomes, we humans are nothing special – Moran makes a convincing argument that the vast majority of our sloppy human genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced that most of the sequence in our genomes is intricately functional, that the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with this. Laurence A. Moran's clear and incisive book explains why many biologists are so thoroughly mistaken – why our genomes are ‘messy,’ and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their public, privilege the too-fast announcement of novelties and revolutions instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History and Philosophy of Sciences and Techniques , Université Paris 1 Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are
    indeed finely honed by natural selection (like a Swiss watch), but they are
    only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them into the weeds of confusion the way that Dr. Moran does, but the rewards are there to be reaped. A thorough reader will never look at the genome of any living organism or the concept of junk DNA the same way after reading this and will be left wondering how so many baseless claims have made headlines in recent years. In the capable hands of Dr. Moran, we can all learn to untangle facts from unsupported assertions and come away understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your Genome?, Moran brings together evolution, genomics, and decades of scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of elements that exists in our DNA and a no-holds-barred defense of an important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA
    is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member
    of the ENCODE project, everyone who's ever claimed that all non-codimg
    DNA was originally thought to be junk DNA, and in general any biologist who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular
    biology at the AP high school or college level. And just for fun, everyone
    who works for or ever worked for John Mattick.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From John Harshman@21:1/5 to Lawyer Daggett on Sat Apr 29 07:07:58 2023
    On 4/29/23 6:59 AM, Lawyer Daggett wrote:
    On Saturday, April 29, 2023 at 9:35:05 AM UTC-4, John Harshman wrote:
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05 PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided >>>> vision I’ve had ever but with some minor flare and ghosting. Looking >>>> forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life.
    When it comes to our genomes, we humans are nothing special – Moran
    makes a convincing argument that the vast majority of our sloppy human
    genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, >>> Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced
    that most of the sequence in our genomes is intricately functional, that >>> the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with
    this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’ >>> and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a
    furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their >>> public, privilege the too-fast announcement of novelties and revolutions >>> instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on >>> what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History
    and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are >>> indeed finely honed by natural selection (like a Swiss watch), but they are >>> only tiny islands of information embedded in a swamp of evolved gibberish." >>>
    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them >>> into the weeds of confusion the way that Dr. Moran does, but the rewards >>> are there to be reaped. A thorough reader will never look at the genome of >>> any living organism or the concept of junk DNA the same way after reading >>> this and will be left wondering how so many baseless claims have made
    headlines in recent years. In the capable hands of Dr. Moran, we can all >>> learn to untangle facts from unsupported assertions and come away
    understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang >>>
    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your
    Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of
    elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA
    is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member
    of the ENCODE project, everyone who's ever claimed that all non-codimg
    DNA was originally thought to be junk DNA, and in general any biologist
    who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular
    biology at the AP high school or college level. And just for fun, everyone who works for or ever worked for John Mattick.

    Somebody should call Elon.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From erik simpson@21:1/5 to Lawyer Daggett on Sat Apr 29 08:38:56 2023
    On Friday, April 28, 2023 at 7:40:05 PM UTC-7, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05 PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my perspective. Not as much single eye halos and multivision. Best non-aided vision I’ve had ever but with some minor flare and ghosting. Looking forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.
    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life.
    When it comes to our genomes, we humans are nothing special – Moran
    makes a convincing argument that the vast majority of our sloppy human genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced
    that most of the sequence in our genomes is intricately functional, that
    the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with
    this. Laurence A. Moran's clear and incisive book explains why many biologists are so thoroughly mistaken – why our genomes are ‘messy,’ and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code is being revealed whereby the reader is being invited to step inside a furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science, Boston University

    "A serious warning to scientists and science writers who, to seduce their public, privilege the too-fast announcement of novelties and revolutions instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History
    and Philosophy of Sciences and Techniques , Université Paris 1 Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling truth – the DNA sequences that specify our body’s proteins and RNAs are indeed finely honed by natural selection (like a Swiss watch), but they are only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them into the weeds of confusion the way that Dr. Moran does, but the rewards
    are there to be reaped. A thorough reader will never look at the genome of any living organism or the concept of junk DNA the same way after reading this and will be left wondering how so many baseless claims have made headlines in recent years. In the capable hands of Dr. Moran, we can all learn to untangle facts from unsupported assertions and come away understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your Genome?, Moran brings together evolution, genomics, and decades of scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of elements that exists in our DNA and a no-holds-barred defense of an important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA
    is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    That book sounds like a good read. On the subject of genome contents ("junk" or not),
    I've just sent off a tube of spit to 23andme to get an analysis. I want to see among other
    things just how close I am to Homo neaderthalensis. I'll report on the results unless
    they've taken me away.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From *Hemidactylus*@21:1/5 to John Harshman on Sat Apr 29 22:58:48 2023
    John Harshman <john.harshman@gmail.com> wrote:
    On 4/29/23 6:59 AM, Lawyer Daggett wrote:
    On Saturday, April 29, 2023 at 9:35:05 AM UTC-4, John Harshman wrote:
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05 PM UTC-4, *Hemidactylus* wrote: >>>>> Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching >>>>>> your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided >>>>> vision I’ve had ever but with some minor flare and ghosting. Looking >>>>> forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life. >>>> When it comes to our genomes, we humans are nothing special – Moran
    makes a convincing argument that the vast majority of our sloppy human >>>> genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, >>>> Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced >>>> that most of the sequence in our genomes is intricately functional, that >>>> the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with
    this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’ >>>> and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a >>>> furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their >>>> public, privilege the too-fast announcement of novelties and revolutions >>>> instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on >>>> what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History >>>> and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are
    indeed finely honed by natural selection (like a Swiss watch), but they are
    only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them >>>> into the weeds of confusion the way that Dr. Moran does, but the rewards >>>> are there to be reaped. A thorough reader will never look at the genome of >>>> any living organism or the concept of junk DNA the same way after reading >>>> this and will be left wondering how so many baseless claims have made
    headlines in recent years. In the capable hands of Dr. Moran, we can all >>>> learn to untangle facts from unsupported assertions and come away
    understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang >>>>
    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your >>>> Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of >>>> elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA >>>> is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member
    of the ENCODE project, everyone who's ever claimed that all non-codimg
    DNA was originally thought to be junk DNA, and in general any biologist
    who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular
    biology at the AP high school or college level. And just for fun, everyone >> who works for or ever worked for John Mattick.

    Somebody should call Elon.

    Junk DNA is one of those glitches in the matrix that indicate we are living
    in a simulation. That and Berenstain Bears.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From *Hemidactylus*@21:1/5 to erik simpson on Sat Apr 29 22:55:19 2023
    erik simpson <eastside.erik@gmail.com> wrote:
    On Friday, April 28, 2023 at 7:40:05 PM UTC-7, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05 PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided >>> vision I’ve had ever but with some minor flare and ghosting. Looking
    forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.
    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life.
    When it comes to our genomes, we humans are nothing special – Moran
    makes a convincing argument that the vast majority of our sloppy human
    genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer,
    Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him." >>
    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced
    that most of the sequence in our genomes is intricately functional, that
    the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with
    this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’ >> and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code >> is being revealed whereby the reader is being invited to step inside a
    furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science, >> Boston University

    "A serious warning to scientists and science writers who, to seduce their
    public, privilege the too-fast announcement of novelties and revolutions
    instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on
    what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History
    and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling >> truth – the DNA sequences that specify our body’s proteins and RNAs are >> indeed finely honed by natural selection (like a Swiss watch), but they are >> only tiny islands of information embedded in a swamp of evolved gibberish." >>
    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them
    into the weeds of confusion the way that Dr. Moran does, but the rewards
    are there to be reaped. A thorough reader will never look at the genome of >> any living organism or the concept of junk DNA the same way after reading
    this and will be left wondering how so many baseless claims have made
    headlines in recent years. In the capable hands of Dr. Moran, we can all
    learn to untangle facts from unsupported assertions and come away
    understanding why our genome is structured in precisely the way that it is." >>
    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang >>
    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your
    Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of
    elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA
    is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    That book sounds like a good read. On the subject of genome contents ("junk" or not),
    I've just sent off a tube of spit to 23andme to get an analysis. I want to see among other
    things just how close I am to Homo neaderthalensis. I'll report on the results unless
    they've taken me away.

    I hear that if they detect Reptoid DNA above a certain percentage you get a member card for Bohemian Grove.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From jillery@21:1/5 to j.nobel.daggett@gmail.com on Sun Apr 30 03:32:15 2023
    On Sat, 29 Apr 2023 06:59:17 -0700 (PDT), Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:

    On Saturday, April 29, 2023 at 9:35:05?AM UTC-4, John Harshman wrote:
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05?PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching
    your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided
    vision I’ve had ever but with some minor flare and ghosting. Looking >> >> forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life.
    When it comes to our genomes, we humans are nothing special – Moran
    makes a convincing argument that the vast majority of our sloppy human
    genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, >> > Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful
    and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced
    that most of the sequence in our genomes is intricately functional, that >> > the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with
    this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’
    and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a
    furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their >> > public, privilege the too-fast announcement of novelties and revolutions >> > instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on >> > what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History >> > and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are
    indeed finely honed by natural selection (like a Swiss watch), but they are
    only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them >> > into the weeds of confusion the way that Dr. Moran does, but the rewards >> > are there to be reaped. A thorough reader will never look at the genome of
    any living organism or the concept of junk DNA the same way after reading >> > this and will be left wondering how so many baseless claims have made
    headlines in recent years. In the capable hands of Dr. Moran, we can all >> > learn to untangle facts from unsupported assertions and come away
    understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your
    Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of
    elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA
    is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University
    in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member
    of the ENCODE project, everyone who's ever claimed that all non-codimg
    DNA was originally thought to be junk DNA, and in general any biologist
    who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular >biology at the AP high school or college level. And just for fun, everyone >who works for or ever worked for John Mattick.


    John Mattick and Ken Ham are Australia's vengeance for cane toads.

    --
    You're entitled to your own opinions.
    You're not entitled to your own facts.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Lawyer Daggett@21:1/5 to jillery on Sun Apr 30 03:46:02 2023
    On Sunday, April 30, 2023 at 3:35:06 AM UTC-4, jillery wrote:
    On Sat, 29 Apr 2023 06:59:17 -0700 (PDT), Lawyer Daggett <j.nobel...@gmail.com> wrote:
    On Saturday, April 29, 2023 at 9:35:05?AM UTC-4, John Harshman wrote:
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05?PM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching >> >>> your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided
    vision I’ve had ever but with some minor flare and ghosting. Looking >> >> forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life. >> > When it comes to our genomes, we humans are nothing special – Moran >> > makes a convincing argument that the vast majority of our sloppy human >> > genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer,
    Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful >> > and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced >> > that most of the sequence in our genomes is intricately functional, that
    the idea of junk DNA was a mistake that can now be mostly discarded.
    But almost all researchers in molecular evolution have disagreed with >> > this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’
    and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a >> > furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their
    public, privilege the too-fast announcement of novelties and revolutions
    instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book
    on one of the hottest recent controversies in science. A master class on
    what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History >> > and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are
    indeed finely honed by natural selection (like a Swiss watch), but they are
    only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them
    into the weeds of confusion the way that Dr. Moran does, but the rewards
    are there to be reaped. A thorough reader will never look at the genome of
    any living organism or the concept of junk DNA the same way after reading
    this and will be left wondering how so many baseless claims have made >> > headlines in recent years. In the capable hands of Dr. Moran, we can all
    learn to untangle facts from unsupported assertions and come away
    understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your >> > Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of >> > elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA >> > is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University >> > in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member >> of the ENCODE project, everyone who's ever claimed that all non-codimg
    DNA was originally thought to be junk DNA, and in general any biologist >> who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular >biology at the AP high school or college level. And just for fun, everyone >who works for or ever worked for John Mattick.
    John Mattick and Ken Ham are Australia's vengeance for cane toads.

    John is actually a nice man, and a strong advocate for science in general.
    He has a particular hobby horse which is unfortunate but there is room for
    that within science. He's known to do a good job of looking after the young scientists who have worked for him, and there have been many. He's also
    a good rainmaker for a pretty large effort. So I'd suggest substituting
    Rupert Murdoch for John in your little witticism.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From *Hemidactylus*@21:1/5 to Lawyer Daggett on Sun Apr 30 12:42:42 2023
    Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:
    On Sunday, April 30, 2023 at 3:35:06 AM UTC-4, jillery wrote:
    On Sat, 29 Apr 2023 06:59:17 -0700 (PDT), Lawyer Daggett
    <j.nobel...@gmail.com> wrote:
    On Saturday, April 29, 2023 at 9:35:05?AM UTC-4, John Harshman wrote:
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05?PM UTC-4, *Hemidactylus* wrote: >>>>>> Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching >>>>>>> your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my >>>>>> perspective. Not as much single eye halos and multivision. Best non-aided
    vision I’ve had ever but with some minor flare and ghosting. Looking >>>>>> forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life. >>>>> When it comes to our genomes, we humans are nothing special – Moran >>>>> makes a convincing argument that the vast majority of our sloppy human >>>>> genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer, >>>>> Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful >>>>> and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced >>>>> that most of the sequence in our genomes is intricately functional, that >>>>> the idea of junk DNA was a mistake that can now be mostly discarded. >>>>> But almost all researchers in molecular evolution have disagreed with >>>>> this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’
    and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a >>>>> furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their >>>>> public, privilege the too-fast announcement of novelties and revolutions >>>>> instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book >>>>> on one of the hottest recent controversies in science. A master class on >>>>> what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History >>>>> and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are
    indeed finely honed by natural selection (like a Swiss watch), but they are
    only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them >>>>> into the weeds of confusion the way that Dr. Moran does, but the rewards >>>>> are there to be reaped. A thorough reader will never look at the genome of
    any living organism or the concept of junk DNA the same way after reading >>>>> this and will be left wondering how so many baseless claims have made >>>>> headlines in recent years. In the capable hands of Dr. Moran, we can all >>>>> learn to untangle facts from unsupported assertions and come away
    understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your >>>>> Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of >>>>> elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA >>>>> is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University >>>>> in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member >>>> of the ENCODE project, everyone who's ever claimed that all non-codimg >>>> DNA was originally thought to be junk DNA, and in general any biologist >>>> who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular
    biology at the AP high school or college level. And just for fun, everyone >>> who works for or ever worked for John Mattick.
    John Mattick and Ken Ham are Australia's vengeance for cane toads.

    John is actually a nice man, and a strong advocate for science in general.
    He has a particular hobby horse which is unfortunate but there is room for that within science. He's known to do a good job of looking after the young scientists who have worked for him, and there have been many. He's also
    a good rainmaker for a pretty large effort. So I'd suggest substituting Rupert Murdoch for John in your little witticism.


    He seems to have a biased pushback against junk.

    https://www.unsw.edu.au/staff/john-mattick

    In context of noncoding RNAs: “These discoveries mean that the assumption that combinatorial control by transcription factors and other regulatory proteins is sufficient to account for human ontogeny is incorrect, as are circular assumptions about the neutral evolution of the genome.”

    There is often a confusing wordplay between noncoding DNA and “junk” (scare quotes intended). Most laypeople think genes are solely for encoding
    protein producing transcripts, but even the existence of rRNA and tRNA say
    no. I see he’s into noncoding RNAs which is fine, but that’s not enough to refute junk.

    ENCODE may have shown more of the genome lights up than functionally inert
    junk would entail, but the adaptionist bias leads to assumptions that this lighting up as transcription means the resulting transcripts aren’t themselves junk RNA or just the genome being inadvertently tapped for no organismic reason. That’s my sloppy lay perspective.

    People are trying to imply that finding actual function in noncoding (not coding for peptides) regions means junk was a misnomer and that benighted
    junk enthusiasts must have thought noncoding regions were inert. There’s glory in contrarian perspectives that overturn paradigms. You see, those benighted standard social science model folks like Durkheim, Weber, and
    Comte have been refuted by Dawkins, Wilson, Buss, Pinker, and Saad. Finding function in junk is like finding modules in socially plastic mental
    processes.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Lawyer Daggett@21:1/5 to All on Sun Apr 30 07:17:55 2023
    On Sunday, April 30, 2023 at 8:45:06 AM UTC-4, *Hemidactylus* wrote:
    Lawyer Daggett <j.nobel...@gmail.com> wrote:
    On Sunday, April 30, 2023 at 3:35:06 AM UTC-4, jillery wrote:
    On Sat, 29 Apr 2023 06:59:17 -0700 (PDT), Lawyer Daggett
    <j.nobel...@gmail.com> wrote:
    On Saturday, April 29, 2023 at 9:35:05?AM UTC-4, John Harshman wrote: >>>> On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05?PM UTC-4, *Hemidactylus* wrote: >>>>>> Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their >>>>>>> idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching >>>>>>> your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my >>>>>> perspective. Not as much single eye halos and multivision. Best non-aided
    vision I’ve had ever but with some minor flare and ghosting. Looking
    forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book >>>>> that will make you wonder afresh at the molecular intricacies of life. >>>>> When it comes to our genomes, we humans are nothing special – Moran >>>>> makes a convincing argument that the vast majority of our sloppy human >>>>> genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer,
    Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful >>>>> and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry >>>>> and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced >>>>> that most of the sequence in our genomes is intricately functional, that
    the idea of junk DNA was a mistake that can now be mostly discarded. >>>>> But almost all researchers in molecular evolution have disagreed with >>>>> this. Laurence A. Moran's clear and incisive book explains why many >>>>> biologists are so thoroughly mistaken – why our genomes are ‘messy,’
    and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences >>>>> and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a >>>>> furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their
    public, privilege the too-fast announcement of novelties and revolutions
    instead of doing a cautious examination of the results. Laurence A. >>>>> Moran has written a deeply honest and extremely well-documented book >>>>> on one of the hottest recent controversies in science. A master class on
    what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History
    and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are
    indeed finely honed by natural selection (like a Swiss watch), but they are
    only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them
    into the weeds of confusion the way that Dr. Moran does, but the rewards
    are there to be reaped. A thorough reader will never look at the genome of
    any living organism or the concept of junk DNA the same way after reading
    this and will be left wondering how so many baseless claims have made >>>>> headlines in recent years. In the capable hands of Dr. Moran, we can all
    learn to untangle facts from unsupported assertions and come away >>>>> understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your >>>>> Genome?, Moran brings together evolution, genomics, and decades of >>>>> scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of >>>>> elements that exists in our DNA and a no-holds-barred defense of an >>>>> important but often ignored fact about the human genome: most of it >>>>> has no function. But Moran shows that, even without function, junk DNA >>>>> is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University >>>>> in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member >>>> of the ENCODE project, everyone who's ever claimed that all non-codimg >>>> DNA was originally thought to be junk DNA, and in general any biologist >>>> who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular >>> biology at the AP high school or college level. And just for fun, everyone
    who works for or ever worked for John Mattick.
    John Mattick and Ken Ham are Australia's vengeance for cane toads.

    John is actually a nice man, and a strong advocate for science in general. He has a particular hobby horse which is unfortunate but there is room for that within science. He's known to do a good job of looking after the young
    scientists who have worked for him, and there have been many. He's also
    a good rainmaker for a pretty large effort. So I'd suggest substituting Rupert Murdoch for John in your little witticism.


    He seems to have a biased pushback against junk.

    https://www.unsw.edu.au/staff/john-mattick

    In context of noncoding RNAs: “These discoveries mean that the assumption that combinatorial control by transcription factors and other regulatory proteins is sufficient to account for human ontogeny is incorrect, as are circular assumptions about the neutral evolution of the genome.”

    There is often a confusing wordplay between noncoding DNA and “junk” (scare
    quotes intended). Most laypeople think genes are solely for encoding
    protein producing transcripts, but even the existence of rRNA and tRNA say no. I see he’s into noncoding RNAs which is fine, but that’s not enough to
    refute junk.

    ENCODE may have shown more of the genome lights up than functionally inert junk would entail, but the adaptionist bias leads to assumptions that this lighting up as transcription means the resulting transcripts aren’t themselves junk RNA or just the genome being inadvertently tapped for no organismic reason. That’s my sloppy lay perspective.

    People are trying to imply that finding actual function in noncoding (not coding for peptides) regions means junk was a misnomer and that benighted junk enthusiasts must have thought noncoding regions were inert. There’s glory in contrarian perspectives that overturn paradigms. You see, those benighted standard social science model folks like Durkheim, Weber, and Comte have been refuted by Dawkins, Wilson, Buss, Pinker, and Saad. Finding function in junk is like finding modules in socially plastic mental processes.

    Mattick has evangelized for a very active, albeit mysterious, role for
    RNA in cellular regulation. In doing so, he has often gone far beyond
    the evidence and indulged in less than forthright rhetoric. In other
    words, he sensationalizes things. Some call it sleaze, some call it
    other things.

    I do think he goes too far to promote himself, and at the expense
    of good science. I've known a few others who also get criticized
    for being good self promoters (but far more tight with their science).
    What I notice is that John gets as much or more criticism for
    being a good promotor, yet he spends much of his energy promoting
    science in general, not just himself, and successfully so.

    I'm glad we have people like Larry to set the record straight, set
    forth an example of clear scientific thinking, and rein in the
    excesses of people like John. And I somewhat tolerant of folks
    like John who push some boundaries, and are good rainmakers.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From jillery@21:1/5 to j.nobel.daggett@gmail.com on Sun Apr 30 22:44:41 2023
    On Sun, 30 Apr 2023 03:46:02 -0700 (PDT), Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:

    On Sunday, April 30, 2023 at 3:35:06?AM UTC-4, jillery wrote:
    On Sat, 29 Apr 2023 06:59:17 -0700 (PDT), Lawyer Daggett
    <j.nobel...@gmail.com> wrote:
    On Saturday, April 29, 2023 at 9:35:05?AM UTC-4, John Harshman wrote:
    On 4/28/23 7:38 PM, Lawyer Daggett wrote:
    On Friday, April 28, 2023 at 8:50:05?PM UTC-4, *Hemidactylus* wrote: >> >> >> Lawyer Daggett <j.nobel...@gmail.com> wrote:
    I can't help but notice the myriad ways that posters
    seem capable of pulling the strings of others and making
    them dance. The stark thing is how oblivious so many
    are to the extent to which they are being manipulated.

    Seriously, it isn't about whether or not you are sitting
    on the North shore or South shore of an important
    river flowing along a significant waterway. It isn't even
    about whether or not you have a compelling argument
    in favor of the prospects afforded to those on your
    side of the River. It's seemingly reduced to your pugnacious
    perspective in support of your antagonistic point of view.

    I damn well think that many here are diametrically opposed
    to people some of you are fighting against. And yet,
    your own inept retorts land squarely in the "you're not
    helping" pumpkin patch.

    Seriously, pause and ask yourself if your contribution is
    helping. Far too often, the appropriate meme is "you're not
    helping." It really isn't necessary to retort to idiots. Their
    idiocy is obvious sans your annotation. To any for whom
    it isn't, they are likely refractive to enlightenment. And watching >> >> >>> your feeble retorts is demoralizing.

    I think I’m stuck on pause. My cataract surgery at 55 changed my
    perspective. Not as much single eye halos and multivision. Best non-aided
    vision I’ve had ever but with some minor flare and ghosting. Looking
    forward to the anesthetic bliss of my other eye.

    Wait. What was the topic? You pulling my strings? I’m waiting for Larry’s
    book. Too much junk in the trunk.

    "What's in Your Genome? is a thought-provoking and pugnacious book
    that will make you wonder afresh at the molecular intricacies of life. >> >> > When it comes to our genomes, we humans are nothing special – Moran >> >> > makes a convincing argument that the vast majority of our sloppy human >> >> > genome is not mysterious genetic treasures but boring old junk."

    Kat Arney, science writer, broadcaster, and author of Rebel Cell: Cancer,
    Evolution, and the New Science of Life’s Oldest Betrayal

    "What’s in Your Genome? is an enormously useful book and a powerful >> >> > and necessary defense of the concept of junk DNA. Moran presents
    a clear summary of how the public can be misled by even the most
    experienced of science writers. We need more outspoken scientists like him."

    W. Ford Doolittle, Professor Emeritus, Department of Biochemistry
    and Molecular Biology, Dalhousie University
    "
    Recently most molecular biologists and genomicists have been convinced >> >> > that most of the sequence in our genomes is intricately functional, that
    the idea of junk DNA was a mistake that can now be mostly discarded. >> >> > But almost all researchers in molecular evolution have disagreed with >> >> > this. Laurence A. Moran's clear and incisive book explains why many
    biologists are so thoroughly mistaken – why our genomes are ‘messy,’
    and full of junk DNA."

    Joe Felsenstein, Professor Emeritus, Departments of Genome Sciences
    and of Biology, University of Washington, Seattle

    "The writing is so crisp and exquisite that it's almost as if a magical code
    is being revealed whereby the reader is being invited to step inside a >> >> > furious scientific debate."

    Lee McIntyre, Research Fellow, Center for Philosophy and History of Science,
    Boston University

    "A serious warning to scientists and science writers who, to seduce their
    public, privilege the too-fast announcement of novelties and revolutions
    instead of doing a cautious examination of the results. Laurence A.
    Moran has written a deeply honest and extremely well-documented book >> >> > on one of the hottest recent controversies in science. A master class on
    what science is and what it must continue to be."

    Michel Morange, Professor Emeritus of Biology, Institute of the History
    and Philosophy of Sciences and Techniques , Université Paris 1
    Panthéon-Sorbonne

    "Laurence A. Moran lucidly explains the science behind an ugly yet thrilling
    truth – the DNA sequences that specify our body’s proteins and RNAs are
    indeed finely honed by natural selection (like a Swiss watch), but they are
    only tiny islands of information embedded in a swamp of evolved gibberish."

    Rosemary J. Redfield, Professor Emerita of Zoology, University of British Columbia

    "Rarely does a science writer respect their audience enough to bring them
    into the weeds of confusion the way that Dr. Moran does, but the rewards
    are there to be reaped. A thorough reader will never look at the genome of
    any living organism or the concept of junk DNA the same way after reading
    this and will be left wondering how so many baseless claims have made >> >> > headlines in recent years. In the capable hands of Dr. Moran, we can all
    learn to untangle facts from unsupported assertions and come away
    understanding why our genome is structured in precisely the way that it is."

    Ethan Siegel, Theoretical Astrophysicist and founder of Starts With A Bang

    "Junk DNA is a concept that’s not well understood, even by most biologists,
    yet arguments about its existence are commonplace. In What’s in Your >> >> > Genome?, Moran brings together evolution, genomics, and decades of
    scientific history to make the case for it. Even if you don’t agree with all
    of his conclusions, you’d benefit from the clarity he brings to the topic."

    John R. Timmer, Science Editor, Ars Technica

    "This book is a clear and fascinating guide to the exotic menagerie of >> >> > elements that exists in our DNA and a no-holds-barred defense of an
    important but often ignored fact about the human genome: most of it
    has no function. But Moran shows that, even without function, junk DNA >> >> > is incredibly interesting."

    Michael White, Associate Professor of Genetics, Washington University >> >> > in St. Louis School of Medicine

    It would be great if some billionaire would send a copy to every member >> >> of the ENCODE project, everyone who's ever claimed that all non-codimg >> >> DNA was originally thought to be junk DNA, and in general any biologist >> >> who's ever said that junk was dead as a concept.

    I'd perhaps prefer to everyone who teaches biology/genetics/molecular
    biology at the AP high school or college level. And just for fun, everyone >> >who works for or ever worked for John Mattick.
    John Mattick and Ken Ham are Australia's vengeance for cane toads.

    John is actually a nice man, and a strong advocate for science in general.
    He has a particular hobby horse which is unfortunate but there is room for >that within science. He's known to do a good job of looking after the young >scientists who have worked for him, and there have been many. He's also
    a good rainmaker for a pretty large effort. So I'd suggest substituting >Rupert Murdoch for John in your little witticism.


    If you had mentioned Rupert Murdoch before, I would have included him
    in my "lttle witticism". But you didn't. Instead you mentioned John
    Mattick, and so I included him. How stupid of me to conform to your
    comments.

    --
    You're entitled to your own opinions.
    You're not entitled to your own facts.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)