Are Vaccines Fueling New Covid Variants?Americans be worried?
By Allysia Finley, Jan. 1, 2023, WSJ
Public-health experts are sounding the alarm about a new Omicron variant dubbed XBB that is rapidly spreading across the Northeast U.S. Some studies suggest it is as different from the original Covid strain from Wuhan as the 2003 SARS virus. Should
It isn’t clear that XBB is any more lethal than other variants, but its mutations enable it to evade antibodies from prior infection and vaccines as well as existing monoclonal antibody treatments. Growing evidence also suggests that repeatedvaccinations may make people more susceptible to XBB and could be fueling the virus’s rapid evolution.
Prior to Omicron’s emergence in November 2021, there were only four variants of concern: Alpha, Beta, Delta and Gamma. Only Alpha and Delta caused surges of infections globally. But Omicron has begotten numerous descendents, many of which have poppedup in different regions of the world curiously bearing some of the same mutations.
“Such rapid and simultaneous emergence of multiple variants with enormous growth advantages is unprecedented,” a Dec. 19 study in the journal Nature notes. Under selective evolutionary pressures, the virus appears to have developed mutations thatenable it to transmit more easily and escape antibodies elicited by vaccines and prior infection.
On Monday, January 2, 2023 at 3:10:37 AM UTC-5, Matt Beasley wrote:
Are Vaccines Fueling New Covid Variants?
By Allysia Finley, Jan. 1, 2023, WSJ
Public-health experts are sounding the alarm about a new Omicron variant
dubbed XBB that is rapidly spreading across the Northeast U.S. Some
studies suggest it is as different from the original Covid strain from
Wuhan as the 2003 SARS virus. Should Americans be worried?
It isn’t clear that XBB is any more lethal than other variants, but its
mutations enable it to evade antibodies from prior infection and
vaccines as well as existing monoclonal antibody treatments. Growing
evidence also suggests that repeated vaccinations may make people more
susceptible to XBB and could be fueling the virus’s rapid evolution.
Prior to Omicron’s emergence in November 2021, there were only four
variants of concern: Alpha, Beta, Delta and Gamma. Only Alpha and Delta
caused surges of infections globally. But Omicron has begotten numerous
descendents, many of which have popped up in different regions of the
world curiously bearing some of the same mutations.
“Such rapid and simultaneous emergence of multiple variants with
enormous growth advantages is unprecedented,” a Dec. 19 study in the
journal Nature notes. Under selective evolutionary pressures, the virus
appears to have developed mutations that enable it to transmit more
easily and escape antibodies elicited by vaccines and prior infection.
"by vaccines and prior infection".
Yes, viruses mutate. Yes, allele frequencies in the population of a virus will change.
That's the very definition of evolution. Yes, alleles that are more successful at reproducing
in the face of a population with immunity from either prior infection or vaccination will
out compete other alleles. The virus will evolve.
Will the populations of vaccinated and unvaccinated drive different 'directions' of
evolution in the virus? Most likely. One of the most remarkable changes seen in
SARS-CoV-2 has been a remarkable increase in infectivity (R0). Many viruses do
that as they adapt to a new host species.
Omicron in particular appears to have pulled a dastardly trick. There are many
indications that an earlier strain did a species crossover to mice, adapted to mouse
ACE2 protein, but then managed to transfer back to humans and then proceeded to again rapidly evolve to this further change in host.
Meanwhile, sensationalized stories that suggest that because viruses evolve vaccination is bad are grossly irresponsible. Viruses evolve to evade immune responses, whether they are immune responses in convalescent people or in vaccinated people. But vaccinated people have the advantage of not having
had to get sick.
Lawyer Daggett <j.nobel.daggett@gmail.com> wrote:
On Monday, January 2, 2023 at 3:10:37 AM UTC-5, Matt Beasley wrote:Given the source being WSJ and the whole “The Biden administration’s monomaniacal focus on vaccines” thing I’m taking this opinion screed with a
Are Vaccines Fueling New Covid Variants?
By Allysia Finley, Jan. 1, 2023, WSJ
Public-health experts are sounding the alarm about a new Omicron variant >>> dubbed XBB that is rapidly spreading across the Northeast U.S. Some
studies suggest it is as different from the original Covid strain from
Wuhan as the 2003 SARS virus. Should Americans be worried?
It isn’t clear that XBB is any more lethal than other variants, but its >>> mutations enable it to evade antibodies from prior infection and
vaccines as well as existing monoclonal antibody treatments. Growing
evidence also suggests that repeated vaccinations may make people more
susceptible to XBB and could be fueling the virus’s rapid evolution.
Prior to Omicron’s emergence in November 2021, there were only four
variants of concern: Alpha, Beta, Delta and Gamma. Only Alpha and Delta
caused surges of infections globally. But Omicron has begotten numerous
descendents, many of which have popped up in different regions of the
world curiously bearing some of the same mutations.
“Such rapid and simultaneous emergence of multiple variants with
enormous growth advantages is unprecedented,” a Dec. 19 study in the
journal Nature notes. Under selective evolutionary pressures, the virus
appears to have developed mutations that enable it to transmit more
easily and escape antibodies elicited by vaccines and prior infection.
"by vaccines and prior infection".
Yes, viruses mutate. Yes, allele frequencies in the population of a
virus will change.
That's the very definition of evolution. Yes, alleles that are more
successful at reproducing
in the face of a population with immunity from either prior infection
or vaccination will
out compete other alleles. The virus will evolve.
Will the populations of vaccinated and unvaccinated drive different
'directions' of
evolution in the virus? Most likely. One of the most remarkable changes seen in
SARS-CoV-2 has been a remarkable increase in infectivity (R0). Many viruses do
that as they adapt to a new host species.
Omicron in particular appears to have pulled a dastardly trick. There are many
indications that an earlier strain did a species crossover to mice,
adapted to mouse
ACE2 protein, but then managed to transfer back to humans and then proceeded >> to again rapidly evolve to this further change in host.
Meanwhile, sensationalized stories that suggest that because viruses evolve >> vaccination is bad are grossly irresponsible. Viruses evolve to evade immune >> responses, whether they are immune responses in convalescent people or in
vaccinated people. But vaccinated people have the advantage of not having
had to get sick.
heavy dosage of anti-BS monoclonals. As for the author someone else has chimed in on another WSJ piece:
https://sciencebasedmedicine.org/fiction/
On 2023-01-02 12:20:09 +0000, *Hemidactylus* said:
Lawyer Daggett <j.nobel...@gmail.com> wrote:
On Monday, January 2, 2023 at 3:10:37 AM UTC-5, Matt Beasley wrote:Given the source being WSJ and the whole “The Biden administration’s monomaniacal focus on vaccines” thing I’m taking this opinion screed with a
Are Vaccines Fueling New Covid Variants?"by vaccines and prior infection".
By Allysia Finley, Jan. 1, 2023, WSJ
Public-health experts are sounding the alarm about a new Omicron variant >>> dubbed XBB that is rapidly spreading across the Northeast U.S. Some
studies suggest it is as different from the original Covid strain from >>> Wuhan as the 2003 SARS virus. Should Americans be worried?
It isn’t clear that XBB is any more lethal than other variants, but its
mutations enable it to evade antibodies from prior infection and
vaccines as well as existing monoclonal antibody treatments. Growing
evidence also suggests that repeated vaccinations may make people more >>> susceptible to XBB and could be fueling the virus’s rapid evolution. >>>
Prior to Omicron’s emergence in November 2021, there were only four >>> variants of concern: Alpha, Beta, Delta and Gamma. Only Alpha and Delta >>> caused surges of infections globally. But Omicron has begotten numerous >>> descendents, many of which have popped up in different regions of the >>> world curiously bearing some of the same mutations.
“Such rapid and simultaneous emergence of multiple variants with
enormous growth advantages is unprecedented,” a Dec. 19 study in the >>> journal Nature notes. Under selective evolutionary pressures, the virus >>> appears to have developed mutations that enable it to transmit more
easily and escape antibodies elicited by vaccines and prior infection. >>
Yes, viruses mutate. Yes, allele frequencies in the population of a
virus will change.
That's the very definition of evolution. Yes, alleles that are more
successful at reproducing
in the face of a population with immunity from either prior infection
or vaccination will
out compete other alleles. The virus will evolve.
Will the populations of vaccinated and unvaccinated drive different
'directions' of
evolution in the virus? Most likely. One of the most remarkable changes seen in
SARS-CoV-2 has been a remarkable increase in infectivity (R0). Many viruses do
that as they adapt to a new host species.
Omicron in particular appears to have pulled a dastardly trick. There are many
indications that an earlier strain did a species crossover to mice,
adapted to mouse
ACE2 protein, but then managed to transfer back to humans and then proceeded
to again rapidly evolve to this further change in host.
Meanwhile, sensationalized stories that suggest that because viruses evolve
vaccination is bad are grossly irresponsible. Viruses evolve to evade immune
responses, whether they are immune responses in convalescent people or in >> vaccinated people. But vaccinated people have the advantage of not having >> had to get sick.
heavy dosage of anti-BS monoclonals. As for the author someone else has chimed in on another WSJ piece:
https://sciencebasedmedicine.org/fiction/I used to follow Science-based Medicine and its sister blog Respectful Insolence, but I stopped after the two chief editors retracted a review
by Harriet Hall, one of their senior editors, in fact one of their
founding editors, of Abigail Shrier's book Irreversible Damage. This
was apparently because the review didn't accept the Woke orthodoxy that
the chief editors had determined to be The Truth. Now I don't agree
with some of the more idiotic posts that appear in this group, but I do agree with Jillery's view that everyone is entitled to their opinions,
and I would strongly oppose any decision not to allow Ron Dean, for
example, to say what he thinks. Apparently the people in charge of Science-based Medicine don't believe in allowing all opinions to be
heard.
--
Athel -- French and British, living in Marseilles for 36+ years; mainly
in England until 1987.
Matt Beasley wrote:Americans be worried?
Are Vaccines Fueling New Covid Variants?
By Allysia Finley, Jan. 1, 2023, WSJ
Public-health experts are sounding the alarm about a new Omicron variant dubbed XBB that is rapidly spreading across the Northeast U.S. Some studies suggest it is as different from the original Covid strain from Wuhan as the 2003 SARS virus. Should
vaccinations may make people more susceptible to XBB and could be fueling the virus’s rapid evolution.It isn’t clear that XBB is any more lethal than other variants, but its mutations enable it to evade antibodies from prior infection and vaccines as well as existing monoclonal antibody treatments. Growing evidence also suggests that repeated
popped up in different regions of the world curiously bearing some of the same mutations.Prior to Omicron’s emergence in November 2021, there were only four variants of concern: Alpha, Beta, Delta and Gamma. Only Alpha and Delta caused surges of infections globally. But Omicron has begotten numerous descendents, many of which have
enable it to transmit more easily and escape antibodies elicited by vaccines and prior infection.“Such rapid and simultaneous emergence of multiple variants with enormous growth advantages is unprecedented,” a Dec. 19 study in the journal Nature notes. Under selective evolutionary pressures, the virus appears to have developed mutations that
"by vaccines and prior infection".--------------------
Yes, viruses mutate. Yes, allele frequencies in the population of a virus will change.
That's the very definition of evolution. Yes, alleles that are more successful at reproducing
in the face of a population with immunity from either prior infection or vaccination will
out compete other alleles. The virus will evolve.
Will the populations of vaccinated and unvaccinated drive different 'directions' of
evolution in the virus? Most likely. One of the most remarkable changes seen in
SARS-CoV-2 has been a remarkable increase in infectivity (R0). Many viruses do
that as they adapt to a new host species.
Omicron in particular appears to have pulled a dastardly trick. There are many
indications that an earlier strain did a species crossover to mice, adapted to mouse
ACE2 protein, but then managed to transfer back to humans and then proceeded to again rapidly evolve to this further change in host.
Meanwhile, sensationalized stories that suggest that because viruses evolve vaccination is bad are grossly irresponsible. Viruses evolve to evade immune responses, whether they are immune responses in convalescent people or in vaccinated people. But vaccinated people have the advantage of not having had to get sick.
Usenet generally works differently. It's common carrier free-for-all.
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