• More of my philosophy about the survival rate of cancer and about life

    From Amine Moulay Ramdane@21:1/5 to All on Mon Mar 20 15:41:09 2023
    Hello,



    More of my philosophy about the survival rate of cancer and about life expectancy for obese men and women as a proof and about weight-loss drugs and about obesity and about cancer and about health and more of my thoughts...

    I am a white arab from Morocco, and i think i am smart since i have also invented many scalable algorithms and algorithms..



    And i invite you to read carefully the following article about the survival rate of all cancers, and it says:

    "The 5-year relative survival rate for all cancers combined that were diagnosed during 2009 through 2015 was 67% overall, 68% in whites, and 62% in Blacks."

    Facts & Figures 2020 Reports Largest One-year Drop in Cancer Mortality

    Read more here:

    https://www.cancer.org/latest-news/facts-and-figures-2020.html


    So i am discovering a pattern with my fluid intelligence, since notice carefully that the survival rate of all cancers is 67% overall even when they are diagnozed , so i think that the dying rate of all cancers is still at 34% in the above article, and
    this confirms what i am saying below about the fact that the 4.2 and 3.5 years shorter lifespan of obese men and women in the study published in the Lancet Diabetes and Endocrinology means that there is a small percentage of the population of BMI between
    25 and 29.9 that can die much more early of cancer, so this proves that overweight of BMI between 25 and 29.9 is not dangerous, since it also causes just a small percentage of cancer in the population of overweight BMI between 25 and 29.9 and even for
    obese of higher BMI.


    More of my philosophy about life expectancy for obese men and women as a proof and about weight-loss drugs and about obesity and about cancer and about health and more of my thoughts...


    So as you have just noticed , i have just said the following:


    "So i am saying that BMI between 25 and 29.9 has only 11% increased risk of death, so i think that it is not dangerous, since statistically the chance is small, so it can kill a small percentage of the population of BMI between 25 and 29.9, so you have
    to understand the statistical significance of it."


    So as a logical proof of it, you have to look at the study published in the Lancet Diabetes and Endocrinology that showed that life expectancy for obese men and women was 4.2 and 3.5 years shorter respectively than people in the entire healthy BMI weight
    range, so this proves what i am saying above, that there a a small percentage in the population of BMI between 25 and 29.9 that can die much more early, so it is why it gives only 4.2 and 3.5 years shorter lifespan in the study published in the Lancet
    Diabetes and Endocrinology, so you can read more about this study in the following article:


    https://www.bbc.com/news/health-46031332


    And read my previous thoughts so that to understand:


    More of my philosophy about weight-loss drugs and about obesity and about cancer and about health and more of my thoughts..

    Here is the four weight-loss interesting drugs that have been approved by the U.S. Food and Drug Administration (FDA) for long-term use, but notice that Wegovy is too expensive:


    1- Qsymia (phentermine/topiramate) is a member of the anorexiants drug
    class and is commonly used for Weight Loss (Obesity/Overweight). The
    cost for Qsymia oral capsule, extended release (3.75 mg-23 mg) is
    around $199 for a supply of 30 capsules, depending on the pharmacy
    you visit, and it can help people lose at least 6 percent of body
    weight.

    2- The cost for naltrexone-bupropion (Contrave) oral tablet, extended
    release (90 mg-8 mg) is around $668 for a supply of 120 tablets,
    depending on the pharmacy you visit, and when combined with lifestyle intervention and modest calorie reduction, seems to be quite
    effective for 6-month and 1-year outcomes for clinically significant
    weight loss (over 5% of total body weight).


    3- Xenical (orlistat) is a member of the peripherally acting
    antiobesity agents drug class and is commonly used for
    Weight Loss (Obesity/Overweight). The cost for Xenical oral
    capsule 120 mg is around $803 for a supply of 90 capsules,
    depending on the pharmacy you visit. You can expect to lose
    around 5% of your starting body weight, every 3 months.
    This means if you currently weigh 90kg, we’d expect you to
    lose 4.5kg in 3 months


    4- And Wegovy's list price is $1,349.02 a month, or more than $16,000
    a year, at the full anti-obesity dose. Patients taking Wegovy lost an
    average of 35 lbs (15.9 kg), or about 15% of their body weigh.


    And read my previous thoughts so that to understand:


    Metformin users had an incredible 54% lower incidence of all cancers compared to the general population. And generally, there’s a 59% increase in the incidence of cancer for every 5-unit increase in body mass index, or BMI, and Body Mass Index (BMI) is
    a person's weight in kilograms (or pounds) divided by the square of height in meters (or feet).


    And read the following so that to notice it:

    http://ohmedgroup.com/articles/metformin-the-worlds-first-true-anti-aging-drug/


    But i think that so that to see the big picture, so here is the other statistics about the body mass index, or BMI:

    BMI 15–18.5: 47% increased risk of death
    BMI 18.5–24.9: no increase (normal)
    BMI 25–29.9: 11% increased risk of death
    BMI 30–34.9: 44% increased risk of death
    BMI 35–39.9: 92% increased risk of death
    BMI 40 or above: 171% increased risk of death


    So as you notice that being overweight of a BMI between 25 and 29.9
    has only 11% increased risk of death, so i think that the dangerous
    BMI is at around 32 or above, so you have to do a calculation of your body mass index, or BMI.


    You can read here so that you understand more:

    https://www.forbes.com/sites/stevensalzberg/2016/09/19/is-it-okay-to-be-a-little-bit-fat-a-new-study-offers-an-answer/?sh=3c553a4f30ca


    More of my philosophy about could more of the protein Menin reverse aging and about scientists that identify anti-aging enzyme for longevity and healthy life and about the groundbreaking study that claims aging can be reversed and more about Rapamycin
    and about Metformin and about cancer and more of my thoughts..


    Could more of the protein Menin reverse aging? New study revives youth

    Read more here:


    https://interestingengineering.com/health/protein-menin-aging-hypothalamus


    Scientists identify anti-aging enzyme for longevity and healthy life

    Read more here:

    https://interestingengineering.com/science/anti-aging-enzyme-longevity-healthy-life


    Groundbreaking study claims aging can be reversed

    Read more here:

    https://interestingengineering.com/science/study-claims-aging-can-be-reversed


    More of my philosophy about Rapamycin and Metformin and about cancer and more of my thoughts..


    With reference to observed survival in diabetic patients initiated with metformin monotherapy [survival time ratio (STR) = 1.0], adjusted median survival time was 15% lower (STR = 0.85, 95% CI 0.81-0.90) in matched individuals without diabetes, so
    diabetics taking metformin were shown to live 15% longer than healthy individuals without diabetes.


    Read more here:

    https://pubmed.ncbi.nlm.nih.gov/25041462/


    And Elixir of life? A breakthrough anti-aging drug may be just around the corner

    Read more here:

    https://interestingengineering.com/health/rapamycin-anti-aging-drug-healthy-younger


    And Metformin was associated with a 31% reduction in the risk of cancer
    and a 35% reduction in the odds of cancer mortality, and Statins exert cancer-preventive effects of 16% reduction in the incidence of cancer
    and a 36% reduction in cancer deaths.

    Read the proof of it in the following articles so that to notice it:

    Here for Metformin:

    https://www.bensnaturalhealth.com/blog/diabetes-health/does-metformin-cause-cancer/

    And here for Statins:

    https://www.webmd.com/cancer/news/20210625/statins-lower-cancer-rate-heart-failure-patients


    And more precision about I3C (Indole-3-carbinol) and cancer..

    I have just read the following article, i invite you to read it:

    Broccoli and Brussels sprouts: Cancer foes

    https://news.harvard.edu/gazette/story/2019/05/beth-israel-researchers-uncover-anti-cancer-drug-mechanism-in-broccoli/

    But i think that the above article is not speaking about the following
    research that says the following about I3C (Indole-3-carbinol):

    "In vivo studies showed that I3C inhibits the development of different
    cancers in several animals when given before or in parallel to a
    carcinogen. However, when I3C was given to the animals after the
    carcinogen, I3C promoted carcinogenesis. This concern regarding the
    long-term effects of I3C treatment on cancer risk in humans resulted in
    some caution in the use of I3C as a dietary supplement in cancer
    management protocols"

    Read more here to notice it:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989150/

    So i don't advice to take I3C(Indole-3-carbinol) as a dietary
    supplement, because I3C(Indole-3-carbinol) can reduce the risk of cancer
    , but still you can have cancer even if you take I3C(Indole-3-carbinol)
    , so it is dangerous to take I3C(Indole-3-carbinol) because taking I3C(Indole-3-carbinol) after the carcinogen promotes carcinogenesis(read
    my writing above to notice it).


    And Scientists Make Breakthrough for ‘Next Generation’ Cancer Treatment

    Read more here:

    https://scitechupdates.com/scientists-make-breakthrough-for-next-generation-cancer-treatment/?fbclid=IwAR1CR3BjsX3FlRKLuxfD-tnPgae0D2B7nkqTdVVpquaz0OelBQHqeEw8Nf8


    And the days of cancer relapse are over, thanks to this novel chemoimmunotherapy

    Novel nanoparticles know how to kill cancer for good.

    Read more here:

    https://interestingengineering.com/health/new-chemoimmunotherapy-kill-cancer-for-good


    And I think you will soon be able to pass a blood test that could detect cancers early, read about it here:

    A blood test that could detect cancers early will undergo trials in the U.S.

    Read more here:

    https://interestingengineering.com/health/blood-test-detect-cancers-trials

    And i think the following new treatment will allow to beat cancer,
    so i invite you to read about it carefully in the following article:

    Scientists attempt to beat cancer by suffocating cells within four hours

    https://interestingengineering.com/health/new-treatment-suffocating-cancer-cells


    And read more my thoughts here in the following web link about cancer
    and about new interesting medical treatments and drugs and about
    antibiotic resistance about health and more of my thoughts:

    https://groups.google.com/g/alt.culture.morocco/c/bayBuSxhTEU



    Thank you,
    Amine Moulay Ramdane.

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