• Longevity of sperm and causes of death

    From Joe Mardin@21:1/5 to All on Thu Jul 13 09:53:03 2023
    At 60 million sperm per ejaculation there are about 300 million sperm per 10 ml; find the longest lived 9.9999 percentile and find out why they live (likely well over a month, much longer is possible) find out why compared to The 99th percentile that
    cease living, is it apoptosis, mitochondrial apoptosis, running out of food or essential amino acids or something different?
    If it is apoptosis putting BCL-xL in media and commercial and consumer packaged storage could cause genetically enhanced sperm survival, wikipedia says, "or running out of food or some more Bcl-xL is present, then pores are non-permeable to pro-apoptotic
    molecules and the cell survives"; there are ribosomes at the mitochondria, what mtDNA are they making, what protiens, would more of less of it be of benefit? perhaps sperm run out of essential amino acids, this harms their mitochondria or them and they
    cease living, mitochondrial DNA, which there is not very much of, has epigenetics, what epigenetics of mtDNA causes greatest longevity 99.9999 percentile? if their epigenetics is different than median and 99th percentile survival then try the: Even
    Moreso approach to amplify the beneficial epigenetics of the 9.9999 percentile while duplicating the epigenetics of the longest lived sperm at the tissue culture of genetically enhanced sperm
    Moments of thought doubled or tripled maintaining median or better attention genetics
    Bdnf other gf at box genes,like homeobox genes and other developmental genes that cause double thickness of neocortex are testable in rodents, monkeys; the 99th percentile of neocortex thickness at humans may correlate with higher g, if it does the
    genetic basis of 99th percentile of neocortex thickness is or are intelligence (g like IQ) genes to make part of the homo sapiens, that is peoples' that is humans' germline, additionally developmental genes like homeobox genes but likely different than
    homeobox genes that cause even thicker neocortex than 99th percentile could be new genes that heighten intelligence (g like IQ) could be made part of the human that is homo sapiens germline
    Epigenetic modifications to fetuses during pregnant or 1 day old birthed babies that cause greater neocortex thickness are beneficial, although the entire brain is important, epigenetics that increases the size of the pleasure centers (the pleasureable
    particular shell of the nucleus accumbens, ventral pallidum, various others) and the number of dopamine receptors specifically at the pleasure centers is beneficial; it is also beneficial to increase the size of the sexual pursuit area of the
    hypothalamus at women without androgens at any developmental stage, pineal Positive reinforcers for mice and rats
    Mom scented cotton puffs as positive reinforcers to mice and rats could be nice to the rodents and easy to make
    BT bacillus th. delta endotoxin and VIP proteins are an insecticide, perhaps optimizing its amino acid sequence and protein shape could make a better insecticide

    Colored liposomes with higher light absorbance could be photo activation as a form of activity localization at part of a brain, like neocortex absorption of growth factors (BDNF, NGF, etc) enabled through trans-skull brain surface photoexposure of
    liposomes even though the liposomes are circulating at the entire body they are only active at the neocortex surface where the light shines;
    peak light absorbers, or
    Magnetic hard disk writers with 4 different readable modes per pixel: bump shaped magnetic field, dish, flat and corrugated (BDFC), a modified magnetic write head could make these and i wrote some material about how electron solitons (published) come
    with a magnetic field i think BDFC waveforms are possible with a new kind of write head, perhaps different styles of soliton (i am aware of two, regular and dissipative), also I am sure they have thought about this already but what about the two
    different N or S facing up, with BDCF magnetic forms and N/S at each of them that is 8 times more data with slight variations to read write heads at a magnetic hard disk; I previously wrote at a paper notebook about a way to make a 200 terabyte 3.5" hard
    drive, with this that is 8 times more, 1.6 petabytes at a 3.5" hard drive, suggesting that most of the time 200 Tb of data could be written 8 times in various locations to minimize read head seek time by having the data near wherever the read head likes
    to hang out at, the perimeter has the highest velocity (7200,rpm at 2020) so always storing to the perimeter first gives highest data rate; also comparing the magnetizing ability of an electron soliton running through the write head to produce something
    like an EM field magnetic soliton it is possible deep full depth of magnetic domain magnetization is possible as well as tapering /| magnetic form at the HDD pixel size, if these can be distinguished by a read head that is another factor of 2 bringing
    the HDD (3.5") to 3.2 petabytes
    Mini optical proteolytic cup pee or plucked hair test with 7 colors times two line types (dashed or solid) and 3 cup depths (bottom, mid, top), also the cups could come in pairs or triples like a : or tricup with a common wide fluid sharing channel at
    the base and super hydrophobic wicking to the other cups to make 3 48 on/off variables per cup, a mini jelly cup (10-15 gram) is $5 for 600 on alibaba (cup to diagnose and a delicious cup you eat which makes something that collects chemicals for more
    better diagnostic ability, perhaps creamy pudding as the protein makes it nontransparent; gene test) so less than a cent a cup for jello that does its own proteolytic and wicking chemistry with see-through sides; 144 different chemicals tested for
    Another possibility is a delicious drink in a sealed cup alibaba 1 cent as a jelly treat, you drink the evening before and a cup you pee into in the morning, the cup you drink has enteric coated liposamal antibodies to 146 different chemicals, these glom
    chemicals/proteins in the bloodstream and then you pee them out in the morning, perhaps the antibody has a CPP that localizes to kidneys, this concentrates chemicals of interest for when you pee in the indicator cup, it is my perception antibody based
    stains to antibodies concentrates (too weak to test antibodies, layered twice become strong enough to see) antibodies and increases detectability and contrast, the drink and cup two pack could come connected and you just detach the drink and go
    Personality and other psychology test written around questions that have .9 correlation with some chemical, its kind of crude but estrogen goes with women, usually so 2/3 likely to be F, feelers, yet screening like 100 variations on feeler questions
    might find some that are .9 correlated with estrogen presence, and meaningfully how much, similar with testosterone and mbti thinker type (2/3rds of males are thinker type), this could be combined with cortisol to diagnose likeliness of stressed or
    unstressed F-feelings, it is possible endogenous phenyl ethyl amines or dopamine post chemicals (dopamine oxide?) Telling how happy (PEA) and motivating (dopamine oxide) your life is, at .9 as corroborated with the concepts/wording of the product
    developmental test; other chemicals could be anything associated with longevity although I don't think the sensitivity is enough for telomeres, creatinine to diagnose heart trouble early, and, as a hair follicle/root is damp with what I think might be
    plasma when it comes out, anything beneficially diagnostic that is in plasma such as globulin ratios, iron to diagnose anemia, very easily treated to give people more energy, also some measure of fertility, like month long circulation globulin-bound sex
    hormones, at 2 cent at alibaba dollar store pregnancy tests detect really minute amounts of human chorionic gonadatropin really minute amounts of things bound to plasma (dampness at hair root, proteolytic product of hair root digest) that show 1-3 month
    body averages possibly with sugar-reacted globin bound products at plasma correlating to blood sugar, just as dopamine has a circulating post neurotransmitter form I read about (similar to the words dopamine oxide) 5HT (serotonin) may also have a "5HT
    oxide", the amount of and balance of many (20? 40?) Different neurotransmitter oxides (more AMPA means you are smart(er), more oxytocin more feeling and affiliative, schizophrenia test results before you have symptoms
    Pee test plant band aid, farmers could put a cellulosease containing dot band aid on plants and color responsive antibodies could tell the farmer a plurality of useful things, likely 1-2 cents at alibaba and less than 6 cents per dot
    Mosquito terminator that might reduce malaria; there are audio mosquito repellers, are there audio mosquito attractors, if there are you could put them at the lid of a pitcher of soapy water that takes a couple of months to evaporate, the mosquito's fly
    in, land on the sponge and cannot fly out; another possibility is simply a roll of flypaper (mosquito paper) with a battery powered photovoltaic all night intermittent acoustic effect
    The internet says male mosquito's are attracted to female mosquito sounds, but I do not know what sounds, if any female mosquitos are attracted to
    Could an immunization to mosquito toxin which is perhaps a dermis dissolving protease or also an anticoagulant make mosquito bites less itchy and annoying? One dose might (might not) last a lifetime and relieve children and adults from discomfort
    There may be a genetic reason why some people get fewer mosquito and other bug bites, using protocols (approximately described) at my paper notes, these genes, if non deleterious and supporting pale white attractive (porcelain) skin are beneficial to
    place at homo sapiens' that is humans' that is people's germline genome
    The internet says mosquito's do not respond to light, but the internet also mentions what I perceive is a scientific study that they are 500% more active (I do not know what active means here)at the full moon so the unique spectrum of moonlight could
    make them more active, a dollar store photovoltaic lawn ornament over a built in water container and a moon spectrum LED could possibly attract them, or, if active means they fly away from things with moonlight on them aiming moonlight LEDs at doors and
    bedspread in a sleep compatible way could cause them to be active about staying out of rooms and also avoiding people in bed, people with socializing backyards could put up moonlight LED floodlights which might even work during the day or at dusk
    Moonlight LED augmented drone, optimally silent to very quiet, perhaps with egg whisk rotors replacing propellers (paper notes), drags electrified mesh over mosquito's it spots using IR night vision, as most B&W webcams have/had. The cheapest
    rechargeable plausible drone on alibaba is $3.00 with WiFi, which is beneficial as a PC can read the drone's video and tell it where to go, also a raquet bug zapper on alibaba is 15 cents, the camera might be 10 cents so the mosquito zapping WiFi drone
    might be $3.25 plus land-on wireless recharger(60 cents at alibaba), this could also be a new IoT (internet of things) appliance with more than a billion units globally if it works well, I think $3.25 + 60 cents, $3.85 is affordable at the developing
    world where a mosquito bednet is about $2-4, but is 23 cents to 95 cents (insecticide treated) at alibaba
    I have never heard of polymer weave bednet, window and door(?) Mosquito netting that approaches transparency from the polymer fibers, which are actually tubes being gradient refractive index sideways along-length lenses (GRIN lenses)
    Could there be such a thing as a fun mosquito bednet, lingerie look may be appealing to some, as could doll/video character themes for children; putting a fun 3 month (2 layers nested) helium mylar balloon inside the net might be fun, I have not seen one
    with extra fabric that drapes over a nightstand with for example a glass of water, a book, a tablet computer, a sexual pleasure vibrator, a netting accessible nightstand drawer, and a clock or phone on it
    Noise cancellation directed confocal piezo speakers could remove mosquito noises by aiming at people's ears while being far from their head, this would work on other buzzing insects as well, this is somewhat comparable to two groups of five wired piezo
    buzzers for 2 cents each plus the computational sophistication of an alibaba 1 cent microcontroller so, from some perspectives this is 11 cents, from other perspectives that include wires and wall plugs and ac/DC converters it is 54 cents, as a guess,
    from alibaba parts, it may not work very well without a camera to see and track ear location (another 10 cents)
    Beaded curtains at interior doors may keep mosquito's from passing doors particularly if the beaded curtain has an acoustic mosquito repeller aimed at the beads which are structured to resonate to a second emitted nonaudible frequency that causes the
    specially shaped beads to each emit bug repelling frequencies on its own
Powering these things around the bedroom at the developing world makes me think of $3 drones carrying (alibaba)10 cent rechargeable power banks, a library of 10 power banks could
    fly around the developing or developed world at about $4.11 (camera and microcontroller also) for the grouperid
Conductive polymer like rubber, even conductive carbon or better conductive rubber is corrosionless, waterproof and wipes clean at OO
    wireless charger and drop/casually an inexactly placed power bank to power the wireless charger that then charges a phone, tablet, or even a drone, plaid power traces support simply putting power bank brick on top of each other
    Things on alibaba are noticeably cheaper than Fred Meyer, Amazon, or EBay, part of this I think is removing all the break-bulk and middlemen from the distribution, and products sometimes come direct from the factory, but if things continued to be
    displayed for planned and impulse pickup at showrooms called"stores" during 2020 then a way to remove middlemen and stock showrooms is of value, a new form of shrink wrap product that is drone friendly could make this functional: 1) print all six sides
    of a box or other object with invisible barcodes, these barcodes are only visible to ir cameras like those on the stocking drones, likely a QR (2D) code this would contain UPC code and more information 2) the plastic the pallet was wrapped in a: polymer,
    form, and wrap style that a drone's laser could cut through (perhaps transparent ir absorbing plastic, a compact disk players laser diode can pop a balloon so a cutting grid projecting laser is likely near 10 cents on alibaba and the camera and computer
    can verify there are no people around and like a backup vehicle it can beep for 5 seconds to keep people away from it before lighting the all pallet side cutting grid 3) with the pallet wrap out of the way the flying drones grab the stuff and take it to
    the shelves or other CAD encoded 3D location (put the new empty flowerpot on the glass table next to the outdoor lounge furniture) 4) enumerate the stuff on the pallet and update showroom and manufacturer's database; during 2020 there was already
    research on automated stocking


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    All technologies, ideas, and inventions of Treon Sebastian Verdery are public domain at JUly 8,2023AD and previously, as well as after that date

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