• Omnipod 5, Dexcom G7, & other devices in 2022?

    From _@21:1/5 to All on Fri Jan 7 12:19:15 2022
    The following excerpts describe the upcoming
    Omnipod 5 & Dexcom G7 devices.

    See the article for details of other devices from
    Tandem, Medtronic, Eversense, Lilly, & Abbott
    (Freestyle Libre 3 which remains a mysterious
    device not yet approved in the U.S. even though
    it was approved in Europe in 2020):

    - - -
    January 5 2022 https://www.healthline.com/diabetesmine/new-diabetes-technology-in-2022
    - - -

    [with clarifying inserts, not part of original
    article, included in brackets]

    ...

    Omnipod 5 tubeless system

    ... new Omnipod 5 tubeless insulin pump system
    ... from ... Insulet Corp. This will be the company’s
    first closed loop system that automates insulin
    delivery based on CGM data.

    ... It connects the Omnipod tubeless patch pump
    to a CGM via a smart algorithm, allowing for auto-
    matic insulin dosing adjustments [i.e., basal insu-
    lin adjustments based on CGM glucose levels].

    It’s based on the Omnipod DASH platform ... . It
    will first be available to connect with the Dexcom
    CGM & later with Abbott’s FreeStyle Libre.

    Omnipod 5 is also set to bring mobile app control
    & insulin dosing, eliminating the need to carry a
    separate Personal [Disparate High Glucose Condi-
    tions] Manager (PDM) around to control the Omni-
    pod.

    Omnipod 5 ... had been originally planned for 2020
    but was delayed because of COVID-19 & that didn’t
    materialize for 2021. However, many believe it will
    get FDA approval in the first half of 2022 [hmmm,
    that remains to be seen, & whenever it's approved,
    it's likely to be awhile after that before it's widely
    available to individuals].

    ...

    Dexcom G7

    This latest model of the Dexcom CGM [currently,
    Dexcom G6 is available] is set to bring a signifi-
    cant form-factor change: a combined sensor &
    transmitter design.

    Here are the G7 details:

    o Fully disposable. Unlike Dexcom CGM models to
    date, the G7 will be fully disposable. ... there will no
    longer be a separate transmitter with a 3-month bat-
    tery life. Instead, the sensor & transmitter will be int-
    egrated, and once the sensor’s run is finished, you’ll
    dispose of the whole combined unit.

    o Wear time. While it will start off at 10-day wear like
    the current G6 version, the G7 is designed to eventu-
    ally support longer wear for up to 14 to 15 days. No
    fingerstick calibrations will be required, but that will
    remain optional.

    o Thinner. Dexcom says the G7 will be the thinnest
    ... of its CGM sensors yet at 60 percent smaller.

    o Decision support. Dexcom has talked a lot about
    wanting to integrate software features like dosing
    assistance & information & prompts that help users
    make better health choices based on their CGM [glu-
    cose levels].

    [For Omnipod 5 users, difficult to determine if that
    will augment the auto-insulin pump dosages in any
    helpful manner, or not]

    In recent investor updates, Dexcom ... explained
    that the company plans to eventually have different
    versions of the G7 for different groups of users. ...

    Dexcom said ... in late October 2021 it had planned
    to file the G7 with the FDA in “a few weeks,” ... [the
    article doesn't say the G7 has been submitted yet
    & it's unknowable if the device will be widely avail-
    able to end users by the end of 2022 or not].

    [The after-insurance costs of the Omnipod 5 &
    Dexcom G7, until they become widely available
    or pricing announcements are made, difficult to
    ascertain if they will be less or more expensive
    than the current Omnipod & Dexcom G6 devices;
    also, if one has current glucose levels < 5.6 with ...

    ... current devices, mysterious if the new devices
    will be able to maintain those low HbA1c levels,
    decrease risks from too low glucose levels, in-
    crease safety & allow for fewer awakenings while
    asleep to make sure glucose levels are acceptable
    or are in need of insulin to lower glucose levels ...

    ... that are too high or glucose-raising carbs in food
    or drink to respond to rapidly lowering or already-
    too-low glucose levels. Ideally, the new devices
    will have positive impacts on HbA1c & increased
    safety & lower costs, but right now, those are mere
    hopes, & only actual usage in each individual will
    tell the tale.

    i.e. In all the Omnipod 5 tests I've seen, very few
    individuals have HbA1c < 5.6, & I can't recall see-
    ing any tests of the Dexcom G7, so it's unclear
    what the impact/import of those devices will be
    compared to current devices (probably positive,
    but impossible to know beforehand).]

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~

    INSULINITIS (ISLIT)

    New SUPERIOR clarifying name for near-
    total to total loss of endogenous insulin https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    The overwhelming majority of Islit caused by
    autoimmune attacks on pancreatic beta cells
    (Insulitis Islit) but there are

    o 15 specific types of rapid onset Islit, a
    rare condition (only present in < one-half
    of 1% of Americans & in a much lower rate
    in most of the world), when present is typ-
    ically diagnosed at age under 30
    (50% at age < 18, 20% at age 19 to 29)

    o 1 slow onset specific type, Latent Autoim-
    mune Islit, frequency unknown but per a
    recent report, misdiagnosed as Cellosis
    (new clarifying name for type 2 diabetes)
    almost 40% of the time due to its slow
    onset and its occurrence typically at age
    over 30

    Old outdated anachronistic name for Islit is
    type 1 diabetes, confusing in that diabetes
    without clarifier is often used to describe
    this condition which is 1 of the 7 Disparate
    High Glucose Conditions (DHGCs).

    That makes figuring out which DHGC is actu-
    ally being referred to (and it can be any one,
    or some, or all of them when the diabetes
    or diabetic word is used without clarifier)
    confusing / difficult: https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg https://prohuman.net/pix2/diabetesdiabeticconfusion.jpg https://prohuman.net/pix2/diabetesdiabeticendingthemisunderstanding.jpg

    - - -

    It's estimated that 5% to 11% of Islit individuals
    will die from severe hypoglycemia, the highest
    risk of that being while sleeping (i.e., dead-in-
    bed syndrome).

    - - -

    Shocking Misdiagnoses of Islit at All Ages https://clinical.diabetesjournals.org/content/diaclin/37/3/276/F1.large.jpg

    at ages 0-6 ........ 21%
    at ages 7-12 ...... 15%
    at ages 13-17 .... 14%
    at ages 18-29 .... 30%
    at ages 30-39 .... 46%
    at ages 40-49 .... 48%
    50+ .................... 55%

    Table showing Islit primarily misdiagnosed as
    - Cellosis (new superior clarifying name for
    type 2 diabetes) in adults, 76.8%
    - Flu/Viral Infection in children, 53.7% https://clinical.diabetesjournals.org/highwire/markup/8771/expansion

    Details on Shocking Islit Misdiagnoses &
    Islit Ketoacidosis is the Leading Cause
    of Death in Islit Children & Young Adults https://clinical.diabetesjournals.org/content/37/3/276

    - - -

    Insulin / Insulin Pump / CGM I use

    Fiasp Ultra-Fast-Acting Insulin in a
    tubeless Omnipod insulin pump catheter
    placed into skin / pod with adhesive
    stuck onto skin every 80 hours, control
    via PDM (Personal Data Manager) https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg

    Dexcom G6 CGM (continuous glucose monitor) https://prohuman.net/pix2/Dexcom_G6_CGM.jpg

    - - -

    Diabetes Bubble / Diabetes Bubble Burst
    Outstanding! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    C.ure I.nsulinitis A.ssociation
    Please! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    Great! https://prohuman.net/glucoseanomaliesresearch.htm

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Clutterfreak@21:1/5 to All on Fri Jan 7 17:19:36 2022
    On 1/7/2022 2:19 PM, _ wrote:
    The following excerpts describe the upcoming
    Omnipod 5 & Dexcom G7 devices.

    See the article for details of other devices from
    Tandem, Medtronic, Eversense, Lilly, & Abbott
    (Freestyle Libre 3 which remains a mysterious
    device not yet approved in the U.S. even though
    it was approved in Europe in 2020):

    - - -
    January 5 2022 https://www.healthline.com/diabetesmine/new-diabetes-technology-in-2022
    - - -

    [with clarifying inserts, not part of original
    article, included in brackets]

    ...

    Omnipod 5 tubeless system

    ... new Omnipod 5 tubeless insulin pump system
    ... from ... Insulet Corp. This will be the company’s
    first closed loop system that automates insulin
    delivery based on CGM data.

    ... It connects the Omnipod tubeless patch pump
    to a CGM via a smart algorithm, allowing for auto-
    matic insulin dosing adjustments [i.e., basal insu-
    lin adjustments based on CGM glucose levels].

    It’s based on the Omnipod DASH platform ... . It
    will first be available to connect with the Dexcom
    CGM & later with Abbott’s FreeStyle Libre.

    Omnipod 5 is also set to bring mobile app control
    & insulin dosing, eliminating the need to carry a
    separate Personal [Disparate High Glucose Condi-
    tions] Manager (PDM) around to control the Omni-
    pod.

    Omnipod 5 ... had been originally planned for 2020
    but was delayed because of COVID-19 & that didn’t
    materialize for 2021. However, many believe it will
    get FDA approval in the first half of 2022 [hmmm,
    that remains to be seen, & whenever it's approved,
    it's likely to be awhile after that before it's widely
    available to individuals].

    ...

    Dexcom G7

    This latest model of the Dexcom CGM [currently,
    Dexcom G6 is available] is set to bring a signifi-
    cant form-factor change: a combined sensor &
    transmitter design.

    Here are the G7 details:

    o Fully disposable. Unlike Dexcom CGM models to
    date, the G7 will be fully disposable. ... there will no
    longer be a separate transmitter with a 3-month bat-
    tery life. Instead, the sensor & transmitter will be int-
    egrated, and once the sensor’s run is finished, you’ll
    dispose of the whole combined unit.

    o Wear time. While it will start off at 10-day wear like
    the current G6 version, the G7 is designed to eventu-
    ally support longer wear for up to 14 to 15 days. No
    fingerstick calibrations will be required, but that will
    remain optional.

    o Thinner. Dexcom says the G7 will be the thinnest
    ... of its CGM sensors yet at 60 percent smaller.

    o Decision support. Dexcom has talked a lot about
    wanting to integrate software features like dosing
    assistance & information & prompts that help users
    make better health choices based on their CGM [glu-
    cose levels].

    [For Omnipod 5 users, difficult to determine if that
    will augment the auto-insulin pump dosages in any
    helpful manner, or not]

    In recent investor updates, Dexcom ... explained
    that the company plans to eventually have different
    versions of the G7 for different groups of users. ...

    Dexcom said ... in late October 2021 it had planned
    to file the G7 with the FDA in “a few weeks,” ... [the
    article doesn't say the G7 has been submitted yet
    & it's unknowable if the device will be widely avail-
    able to end users by the end of 2022 or not].

    [The after-insurance costs of the Omnipod 5 &
    Dexcom G7, until they become widely available
    or pricing announcements are made, difficult to
    ascertain if they will be less or more expensive
    than the current Omnipod & Dexcom G6 devices;
    also, if one has current glucose levels < 5.6 with ...

    ... current devices, mysterious if the new devices
    will be able to maintain those low HbA1c levels,
    decrease risks from too low glucose levels, in-
    crease safety & allow for fewer awakenings while
    asleep to make sure glucose levels are acceptable
    or are in need of insulin to lower glucose levels ...

    ... that are too high or glucose-raising carbs in food
    or drink to respond to rapidly lowering or already-
    too-low glucose levels. Ideally, the new devices
    will have positive impacts on HbA1c & increased
    safety & lower costs, but right now, those are mere
    hopes, & only actual usage in each individual will
    tell the tale.

    i.e. In all the Omnipod 5 tests I've seen, very few
    individuals have HbA1c < 5.6, & I can't recall see-
    ing any tests of the Dexcom G7, so it's unclear
    what the impact/import of those devices will be
    compared to current devices (probably positive,
    but impossible to know beforehand).]

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~

    INSULINITIS (ISLIT)

    New SUPERIOR clarifying name for near-
    total to total loss of endogenous insulin https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    The overwhelming majority of Islit caused by
    autoimmune attacks on pancreatic beta cells
    (Insulitis Islit) but there are

    o 15 specific types of rapid onset Islit, a
    rare condition (only present in < one-half
    of 1% of Americans & in a much lower rate
    in most of the world), when present is typ-
    ically diagnosed at age under 30
    (50% at age < 18, 20% at age 19 to 29)

    o 1 slow onset specific type, Latent Autoim-
    mune Islit, frequency unknown but per a
    recent report, misdiagnosed as Cellosis
    (new clarifying name for type 2 diabetes)
    almost 40% of the time due to its slow
    onset and its occurrence typically at age
    over 30

    Old outdated anachronistic name for Islit is
    type 1 diabetes, confusing in that diabetes
    without clarifier is often used to describe
    this condition which is 1 of the 7 Disparate
    High Glucose Conditions (DHGCs).

    That makes figuring out which DHGC is actu-
    ally being referred to (and it can be any one,
    or some, or all of them when the diabetes
    or diabetic word is used without clarifier)
    confusing / difficult: https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg https://prohuman.net/pix2/diabetesdiabeticconfusion.jpg https://prohuman.net/pix2/diabetesdiabeticendingthemisunderstanding.jpg

    - - -

    It's estimated that 5% to 11% of Islit individuals
    will die from severe hypoglycemia, the highest
    risk of that being while sleeping (i.e., dead-in-
    bed syndrome).

    - - -

    Shocking Misdiagnoses of Islit at All Ages https://clinical.diabetesjournals.org/content/diaclin/37/3/276/F1.large.jpg

    at ages 0-6 ........ 21%
    at ages 7-12 ...... 15%
    at ages 13-17 .... 14%
    at ages 18-29 .... 30%
    at ages 30-39 .... 46%
    at ages 40-49 .... 48%
    50+ .................... 55%

    Table showing Islit primarily misdiagnosed as
    - Cellosis (new superior clarifying name for
    type 2 diabetes) in adults, 76.8%
    - Flu/Viral Infection in children, 53.7% https://clinical.diabetesjournals.org/highwire/markup/8771/expansion

    Details on Shocking Islit Misdiagnoses &
    Islit Ketoacidosis is the Leading Cause
    of Death in Islit Children & Young Adults https://clinical.diabetesjournals.org/content/37/3/276

    - - -

    Insulin / Insulin Pump / CGM I use

    Fiasp Ultra-Fast-Acting Insulin in a
    tubeless Omnipod insulin pump catheter
    placed into skin / pod with adhesive
    stuck onto skin every 80 hours, control
    via PDM (Personal Data Manager) https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg

    Dexcom G6 CGM (continuous glucose monitor) https://prohuman.net/pix2/Dexcom_G6_CGM.jpg

    - - -

    Diabetes Bubble / Diabetes Bubble Burst
    Outstanding! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    C.ure I.nsulinitis A.ssociation
    Please! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    Great! https://prohuman.net/glucoseanomaliesresearch.htm

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~


    Diabetes is curable these days. Read Jason Fung's "The Diabetes code".

    --
    This email has been checked for viruses by Avast antivirus software. https://www.avast.com/antivirus

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From _@21:1/5 to All on Sat Jan 8 11:58:33 2022
    (pardon for re-post to fix annoying typos)

    First off, Islit (Insulinitis, near-total to total loss of
    endogenous insulin), the condition I've had for over
    61 years (since age 5) requires exogenous insulin
    to try to stay alive.

    In < 1% of severe cases, pancreas or islet cell trans-
    plants, which require risky immunosuppressants &
    which rarely last > 10 years, can, in a very small per-
    cent of Islit individuals, provide a treatment free of
    exogenous insulin, but in close to all cases, the ...

    ... absence of exogenous insulin is temporary & in
    almost all cases it must be re-implemented to stay
    alive. Over 99% of Islit individuals don't have a trans-
    plant, though research is ongoing for a better & less
    risky cure or near-cure for Islit.

    Latent Autoimmune Islit, slower onset but the same
    treatment requirements as detailed above.

    The other 5 Disparate High Glucose Conditions?

    In response to someone who ignored the disparate
    causalities, disparate treatments, & disparate risk
    profiles of the over 90 specific types of 7 Disparate
    High Glucose Conditions, see the following enlight-
    enment that I first posted on August 3 2021: https://groups.google.com/g/misc.health.diabetes/c/gkjn-dR7wQE/m/8u3NraSiAwAJ

    First off, the word "diet", the particular "diet" the
    poster I'm replying to implied was a 'cure' for all
    7 Disparate High Glucose Conditions, refer to the
    following, noting that only 1 specific type (Preven-
    table Cellosis) of 1 of the 7 Disparate High Glucose
    Conditions is involved in prevention, all other ...

    ... Disparate High Glucose Conditions are non-pre-
    ventable and incurable at the present time:

    - - -
    March 24 2015

    The Weight of the Evidence

    97 percent of dieters regain everything they
    lost and then some within three years https://slate.com/technology/2015/03/diets-do-not-work-the-thin-evidence-that-losing-weight-makes-you-healthier.html
    - - -

    Ketogenic Diet Warnings

    - - -
    August 3 2021

    Keto diets are a ‘disease-promoting disaster,’
    researchers warn
    https://www.studyfinds.org/keto-disease-promoting-disaster/
    - - -

    - - -
    July 28 2021

    Most Comprehensive Review Yet of Keto Diets
    Finds Heart Risks, Cancer Risk, Dangers to
    Pregnant Women and Kidney Patients https://www.pcrm.org/news/news-releases/most-comprehensive-review-yet-keto-diets-finds-heart-risks-cancer-risk-dangers
    - - -

    ...

    Five key findings of the Frontiers in Nutrition
    review paper are:

    1. Keto diets may be especially unsafe for women
    who are pregnant or may become pregnant—low-
    carb diets are linked to a higher risk of neural tube
    defects in the baby, even when women take folic
    acid.

    2. Higher-protein keto diets could hasten kidney failure
    in those with kidney disease.

    3. Keto diets raise “bad cholesterol” levels for many
    patients.

    4. Keto diets are presented as a panacea, but they are
    not likely to be safe long term.

    5. Restricting carbohydrate skews the diet toward cancer-
    causing foods. In fact, typical keto foods have been linked
    to an increased risk of heart disease, cancer, Cellosis (the
    Disparate High Glucose Condition present in about 95% of
    those who have any of the 7 DHGCs), & Alzheimer's—often
    the very diseases they are touted to help.

    - - -
    July 16 2021

    Ketogenic Diets and Chronic Disease:
    Weighing the Benefits Against the Risks https://www.frontiersin.org/articles/10.3389/fnut.2021.702802/full
    - - -

    - - - - - - - - - - - - - - - - - - -
    Reference (2010 to 2018):

    Many posts I've made pertaining to the
    particular version of the ketogenic diet
    (a very low carb version) promoted by
    Richard Bernstein https://groups.google.com/g/misc.health.diabetes/search?q=Richard%20Bernstein
    - - - - - - - - - - - - - - - - - - -

    On 1/7/2022 2:19 PM, _ wrote:

    The following excerpts describe the upcoming
    Omnipod 5 & Dexcom G7 devices.

    See the article for details of other devices from
    Tandem, Medtronic, Eversense, Lilly, & Abbott
    (Freestyle Libre 3 which remains a mysterious
    device not yet approved in the U.S. even though
    it was approved in Europe in 2020):

    - - -
    January 5 2022 https://www.healthline.com/diabetesmine/new-diabetes-technology-in-2022
    - - -

    [with clarifying inserts, not part of original
    article, included in brackets]

    ...

    Omnipod 5 tubeless system

    ... new Omnipod 5 tubeless insulin pump system
    ... from ... Insulet Corp. This will be the company’s
    first closed loop system that automates insulin
    delivery based on CGM data.

    ... It connects the Omnipod tubeless patch pump
    to a CGM via a smart algorithm, allowing for auto-
    matic insulin dosing adjustments [i.e., basal insu-
    lin adjustments based on CGM glucose levels].

    It’s based on the Omnipod DASH platform ... . It
    will first be available to connect with the Dexcom
    CGM & later with Abbott’s FreeStyle Libre.

    Omnipod 5 is also set to bring mobile app control
    & insulin dosing, eliminating the need to carry a
    separate Personal [Disparate High Glucose Condi-
    tions] Manager (PDM) around to control the Omni-
    pod.

    Omnipod 5 ... had been originally planned for 2020
    but was delayed because of COVID-19 & that didn’t
    materialize for 2021. However, many believe it will
    get FDA approval in the first half of 2022 [hmmm,
    that remains to be seen, & whenever it's approved,
    it's likely to be awhile after that before it's widely
    available to individuals].

    ...

    Dexcom G7

    This latest model of the Dexcom CGM [currently,
    Dexcom G6 is available] is set to bring a signifi-
    cant form-factor change: a combined sensor &
    transmitter design.

    Here are the G7 details:

    o Fully disposable. Unlike Dexcom CGM models to
    date, the G7 will be fully disposable. ... there will no
    longer be a separate transmitter with a 3-month bat-
    tery life. Instead, the sensor & transmitter will be int-
    egrated, and once the sensor’s run is finished, you’ll
    dispose of the whole combined unit.

    o Wear time. While it will start off at 10-day wear like
    the current G6 version, the G7 is designed to eventu-
    ally support longer wear for up to 14 to 15 days. No
    fingerstick calibrations will be required, but that will
    remain optional.

    o Thinner. Dexcom says the G7 will be the thinnest
    ... of its CGM sensors yet at 60 percent smaller.

    o Decision support. Dexcom has talked a lot about
    wanting to integrate software features like dosing
    assistance & information & prompts that help users
    make better health choices based on their CGM [glu-
    cose levels].

    [For Omnipod 5 users, difficult to determine if that
    will augment the auto-insulin pump dosages in any
    helpful manner, or not]

    In recent investor updates, Dexcom ... explained
    that the company plans to eventually have different
    versions of the G7 for different groups of users. ...

    Dexcom said ... in late October 2021 it had planned
    to file the G7 with the FDA in “a few weeks,” ... [the
    article doesn't say the G7 has been submitted yet
    & it's unknowable if the device will be widely avail-
    able to end users by the end of 2022 or not].

    [The after-insurance costs of the Omnipod 5 &
    Dexcom G7, until they become widely available
    or pricing announcements are made, difficult to
    ascertain if they will be less or more expensive
    than the current Omnipod & Dexcom G6 devices;
    also, if one has current glucose levels < 5.6 with ...

    ... current devices, mysterious if the new devices
    will be able to maintain those low HbA1c levels,
    decrease risks from too low glucose levels, in-
    crease safety & allow for fewer awakenings while
    asleep to make sure glucose levels are acceptable
    or are in need of insulin to lower glucose levels ...

    ... that are too high or glucose-raising carbs in food
    or drink to respond to rapidly lowering or already-
    too-low glucose levels. Ideally, the new devices
    will have positive impacts on HbA1c & increased
    safety & lower costs, but right now, those are mere
    hopes, & only actual usage in each individual will
    tell the tale.

    i.e. In all the Omnipod 5 tests I've seen, very few
    individuals have HbA1c < 5.6, & I can't recall see-
    ing any tests of the Dexcom G7, so it's unclear
    what the impact/import of those devices will be
    compared to current devices (probably positive,
    but impossible to know beforehand).]

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~

    INSULINITIS (ISLIT)

    New SUPERIOR clarifying name for near-
    total to total loss of endogenous insulin https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    The overwhelming majority of Islit caused by
    autoimmune attacks on pancreatic beta cells
    (Insulitis Islit) but there are

    o 15 specific types of rapid onset Islit, a
    rare condition (only present in < one-half
    of 1% of Americans & in a much lower rate
    in most of the world), when present is typ-
    ically diagnosed at age under 30
    (50% at age < 18, 20% at age 19 to 29)

    o 1 slow onset specific type, Latent Autoim-
    mune Islit, frequency unknown but per a
    recent report, misdiagnosed as Cellosis
    (new clarifying name for type 2 diabetes)
    almost 40% of the time due to its slow
    onset and its occurrence typically at age
    over 30

    Old outdated anachronistic name for Islit is
    type 1 diabetes, confusing in that diabetes
    without clarifier is often used to describe
    this condition which is 1 of the 7 Disparate
    High Glucose Conditions (DHGCs).

    That makes figuring out which DHGC is actu-
    ally being referred to (and it can be any one,
    or some, or all of them when the diabetes
    or diabetic word is used without clarifier)
    confusing / difficult: https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg https://prohuman.net/pix2/diabetesdiabeticconfusion.jpg https://prohuman.net/pix2/diabetesdiabeticendingthemisunderstanding.jpg

    - - -

    It's estimated that 5% to 11% of Islit individuals
    will die from severe hypoglycemia, the highest
    risk of that being while sleeping (i.e., dead-in-
    bed syndrome).

    - - -

    Shocking Misdiagnoses of Islit at All Ages https://clinical.diabetesjournals.org/content/diaclin/37/3/276/F1.large.jpg

    at ages 0-6 ........ 21%
    at ages 7-12 ...... 15%
    at ages 13-17 .... 14%
    at ages 18-29 .... 30%
    at ages 30-39 .... 46%
    at ages 40-49 .... 48%
    50+ .................... 55%

    Table showing Islit primarily misdiagnosed as
    - Cellosis (new superior clarifying name for
    type 2 diabetes) in adults, 76.8%
    - Flu/Viral Infection in children, 53.7% https://clinical.diabetesjournals.org/highwire/markup/8771/expansion

    Details on Shocking Islit Misdiagnoses &
    Islit Ketoacidosis is the Leading Cause
    of Death in Islit Children & Young Adults https://clinical.diabetesjournals.org/content/37/3/276

    - - -

    Insulin / Insulin Pump / CGM I use

    Fiasp Ultra-Fast-Acting Insulin in a
    tubeless Omnipod insulin pump catheter
    placed into skin / pod with adhesive
    stuck onto skin every 80 hours, control
    via PDM (Personal Data Manager) https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg

    Dexcom G6 CGM (continuous glucose monitor) https://prohuman.net/pix2/Dexcom_G6_CGM.jpg

    - - -

    Diabetes Bubble / Diabetes Bubble Burst
    Outstanding! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    C.ure I.nsulinitis A.ssociation
    Please! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    Great! https://prohuman.net/glucoseanomaliesresearch.htm

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From _@21:1/5 to All on Sat Jan 8 11:53:13 2022
    First off, Islit (Insulinitis, near-total to total loss of
    endogenous insulin), the condition I've had for over
    61 years (since age 5) requires exogenous insulin
    to try to stay alive.

    In < 1% of severe cases, pancreas or islet cell trans-
    plants, which require risky immunosuppressants &
    which rarely last > 10 years, can, in a very small per-
    cent of Islit individuals, provide a treatment free of
    exogenous insulin, but in close to all cases, the ...

    ... absence of exogenous insulin is temporary & it
    almost all cases it must be re-implemented to stay
    alive. Over 99% if Islit individuals don't have a trans-
    plant, though research is ongoing for a better & less
    risky cure or near-cure for Islit.

    Latent Autoimmune Islit, slower onset but the same
    treatment requirements as detailed above.

    The other 5 Disparate High Glucose Conditions?

    In response to someone who ignored the disparate
    causalities, disparate treatments, & disparate risk
    profiles of the over 90 specific types of 7 Disparate
    High Glucose Conditions, see the following enlight-
    enment that I first posted on August 3 2021: https://groups.google.com/g/misc.health.diabetes/c/gkjn-dR7wQE/m/8u3NraSiAwAJ

    First off, the word "diet", the particular "diet" the
    poster I'm replying to implied was a 'cure' for all
    7 Disparate High Glucose Conditions, refer to the
    following, noting that only 1 specific type (Preven-
    table Cellosis) of 1 of the 7 Disparate High Glucose
    Conditions is involved in prevention, all other ...

    ... Disparate High Glucose Conditions are non-pre-
    ventable and incurable at the present time:

    - - -
    March 24 2015

    The Weight of the Evidence

    97 percent of dieters regain everything they
    lost and then some within three years https://slate.com/technology/2015/03/diets-do-not-work-the-thin-evidence-that-losing-weight-makes-you-healthier.html
    - - -

    Ketogenic Diet Warnings

    - - -
    August 3 2021

    Keto diets are a ‘disease-promoting disaster,’
    researchers warn
    https://www.studyfinds.org/keto-disease-promoting-disaster/
    - - -

    - - -
    July 28 2021

    Most Comprehensive Review Yet of Keto Diets
    Finds Heart Risks, Cancer Risk, Dangers to
    Pregnant Women and Kidney Patients https://www.pcrm.org/news/news-releases/most-comprehensive-review-yet-keto-diets-finds-heart-risks-cancer-risk-dangers
    - - -

    ...

    Five key findings of the Frontiers in Nutrition
    review paper are:

    1. Keto diets may be especially unsafe for women
    who are pregnant or may become pregnant—low-
    carb diets are linked to a higher risk of neural tube
    defects in the baby, even when women take folic
    acid.

    2. Higher-protein keto diets could hasten kidney failure
    in those with kidney disease.

    3. Keto diets raise “bad cholesterol” levels for many
    patients.

    4. Keto diets are presented as a panacea, but they are
    not likely to be safe long term.

    5. Restricting carbohydrate skews the diet toward cancer-
    causing foods. In fact, typical keto foods have been linked
    to an increased risk of heart disease, cancer, Cellosis (the
    Disparate High Glucose Condition present in about 95% of
    those who have any of the 7 DHGCs), & Alzheimer's—often
    the very diseases they are touted to help.

    - - -
    July 16 2021

    Ketogenic Diets and Chronic Disease:
    Weighing the Benefits Against the Risks https://www.frontiersin.org/articles/10.3389/fnut.2021.702802/full
    - - -

    - - - - - - - - - - - - - - - - - - -
    Reference (2010 to 2018):

    Many posts I've made pertaining to the
    particular version of the ketogenic diet
    (a very low carb version) promoted by
    Richard Bernstein https://groups.google.com/g/misc.health.diabetes/search?q=Richard%20Bernstein
    - - - - - - - - - - - - - - - - - - -

    On 1/7/2022 2:19 PM, _ wrote:

    The following excerpts describe the upcoming
    Omnipod 5 & Dexcom G7 devices.

    See the article for details of other devices from
    Tandem, Medtronic, Eversense, Lilly, & Abbott
    (Freestyle Libre 3 which remains a mysterious
    device not yet approved in the U.S. even though
    it was approved in Europe in 2020):

    - - -
    January 5 2022 https://www.healthline.com/diabetesmine/new-diabetes-technology-in-2022
    - - -

    [with clarifying inserts, not part of original
    article, included in brackets]

    ...

    Omnipod 5 tubeless system

    ... new Omnipod 5 tubeless insulin pump system
    ... from ... Insulet Corp. This will be the company’s
    first closed loop system that automates insulin
    delivery based on CGM data.

    ... It connects the Omnipod tubeless patch pump
    to a CGM via a smart algorithm, allowing for auto-
    matic insulin dosing adjustments [i.e., basal insu-
    lin adjustments based on CGM glucose levels].

    It’s based on the Omnipod DASH platform ... . It
    will first be available to connect with the Dexcom
    CGM & later with Abbott’s FreeStyle Libre.

    Omnipod 5 is also set to bring mobile app control
    & insulin dosing, eliminating the need to carry a
    separate Personal [Disparate High Glucose Condi-
    tions] Manager (PDM) around to control the Omni-
    pod.

    Omnipod 5 ... had been originally planned for 2020
    but was delayed because of COVID-19 & that didn’t
    materialize for 2021. However, many believe it will
    get FDA approval in the first half of 2022 [hmmm,
    that remains to be seen, & whenever it's approved,
    it's likely to be awhile after that before it's widely
    available to individuals].

    ...

    Dexcom G7

    This latest model of the Dexcom CGM [currently,
    Dexcom G6 is available] is set to bring a signifi-
    cant form-factor change: a combined sensor &
    transmitter design.

    Here are the G7 details:

    o Fully disposable. Unlike Dexcom CGM models to
    date, the G7 will be fully disposable. ... there will no
    longer be a separate transmitter with a 3-month bat-
    tery life. Instead, the sensor & transmitter will be int-
    egrated, and once the sensor’s run is finished, you’ll
    dispose of the whole combined unit.

    o Wear time. While it will start off at 10-day wear like
    the current G6 version, the G7 is designed to eventu-
    ally support longer wear for up to 14 to 15 days. No
    fingerstick calibrations will be required, but that will
    remain optional.

    o Thinner. Dexcom says the G7 will be the thinnest
    ... of its CGM sensors yet at 60 percent smaller.

    o Decision support. Dexcom has talked a lot about
    wanting to integrate software features like dosing
    assistance & information & prompts that help users
    make better health choices based on their CGM [glu-
    cose levels].

    [For Omnipod 5 users, difficult to determine if that
    will augment the auto-insulin pump dosages in any
    helpful manner, or not]

    In recent investor updates, Dexcom ... explained
    that the company plans to eventually have different
    versions of the G7 for different groups of users. ...

    Dexcom said ... in late October 2021 it had planned
    to file the G7 with the FDA in “a few weeks,” ... [the
    article doesn't say the G7 has been submitted yet
    & it's unknowable if the device will be widely avail-
    able to end users by the end of 2022 or not].

    [The after-insurance costs of the Omnipod 5 &
    Dexcom G7, until they become widely available
    or pricing announcements are made, difficult to
    ascertain if they will be less or more expensive
    than the current Omnipod & Dexcom G6 devices;
    also, if one has current glucose levels < 5.6 with ...

    ... current devices, mysterious if the new devices
    will be able to maintain those low HbA1c levels,
    decrease risks from too low glucose levels, in-
    crease safety & allow for fewer awakenings while
    asleep to make sure glucose levels are acceptable
    or are in need of insulin to lower glucose levels ...

    ... that are too high or glucose-raising carbs in food
    or drink to respond to rapidly lowering or already-
    too-low glucose levels. Ideally, the new devices
    will have positive impacts on HbA1c & increased
    safety & lower costs, but right now, those are mere
    hopes, & only actual usage in each individual will
    tell the tale.

    i.e. In all the Omnipod 5 tests I've seen, very few
    individuals have HbA1c < 5.6, & I can't recall see-
    ing any tests of the Dexcom G7, so it's unclear
    what the impact/import of those devices will be
    compared to current devices (probably positive,
    but impossible to know beforehand).]

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~

    INSULINITIS (ISLIT)

    New SUPERIOR clarifying name for near-
    total to total loss of endogenous insulin https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    The overwhelming majority of Islit caused by
    autoimmune attacks on pancreatic beta cells
    (Insulitis Islit) but there are

    o 15 specific types of rapid onset Islit, a
    rare condition (only present in < one-half
    of 1% of Americans & in a much lower rate
    in most of the world), when present is typ-
    ically diagnosed at age under 30
    (50% at age < 18, 20% at age 19 to 29)

    o 1 slow onset specific type, Latent Autoim-
    mune Islit, frequency unknown but per a
    recent report, misdiagnosed as Cellosis
    (new clarifying name for type 2 diabetes)
    almost 40% of the time due to its slow
    onset and its occurrence typically at age
    over 30

    Old outdated anachronistic name for Islit is
    type 1 diabetes, confusing in that diabetes
    without clarifier is often used to describe
    this condition which is 1 of the 7 Disparate
    High Glucose Conditions (DHGCs).

    That makes figuring out which DHGC is actu-
    ally being referred to (and it can be any one,
    or some, or all of them when the diabetes
    or diabetic word is used without clarifier)
    confusing / difficult: https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg https://prohuman.net/pix2/diabetesdiabeticconfusion.jpg https://prohuman.net/pix2/diabetesdiabeticendingthemisunderstanding.jpg

    - - -

    It's estimated that 5% to 11% of Islit individuals
    will die from severe hypoglycemia, the highest
    risk of that being while sleeping (i.e., dead-in-
    bed syndrome).

    - - -

    Shocking Misdiagnoses of Islit at All Ages https://clinical.diabetesjournals.org/content/diaclin/37/3/276/F1.large.jpg

    at ages 0-6 ........ 21%
    at ages 7-12 ...... 15%
    at ages 13-17 .... 14%
    at ages 18-29 .... 30%
    at ages 30-39 .... 46%
    at ages 40-49 .... 48%
    50+ .................... 55%

    Table showing Islit primarily misdiagnosed as
    - Cellosis (new superior clarifying name for
    type 2 diabetes) in adults, 76.8%
    - Flu/Viral Infection in children, 53.7% https://clinical.diabetesjournals.org/highwire/markup/8771/expansion

    Details on Shocking Islit Misdiagnoses &
    Islit Ketoacidosis is the Leading Cause
    of Death in Islit Children & Young Adults https://clinical.diabetesjournals.org/content/37/3/276

    - - -

    Insulin / Insulin Pump / CGM I use

    Fiasp Ultra-Fast-Acting Insulin in a
    tubeless Omnipod insulin pump catheter
    placed into skin / pod with adhesive
    stuck onto skin every 80 hours, control
    via PDM (Personal Data Manager) https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg

    Dexcom G6 CGM (continuous glucose monitor) https://prohuman.net/pix2/Dexcom_G6_CGM.jpg

    - - -

    Diabetes Bubble / Diabetes Bubble Burst
    Outstanding! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    C.ure I.nsulinitis A.ssociation
    Please! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    Great! https://prohuman.net/glucoseanomaliesresearch.htm

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~

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  • From Clutterfreak@21:1/5 to All on Sat Jan 8 16:40:06 2022
    On 1/8/2022 1:53 PM, _ wrote:
    First off, Islit (Insulinitis, near-total to total loss of
    endogenous insulin), the condition I've had for over
    61 years (since age 5) requires exogenous insulin
    to try to stay alive.


    Did you read the book I mentioned, "The Diabetes Code"? It is a short
    book. Read it and come back here.

    --
    This email has been checked for viruses by Avast antivirus software. https://www.avast.com/antivirus

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  • From _@21:1/5 to Clutterfreak on Sat Jan 8 15:34:14 2022
    On Saturday, January 8, 2022 at 4:40:08 PM UTC-6, Clutterfreak wrote:

    On 1/8/2022 1:53 PM, _ wrote:
    https://groups.google.com/g/misc.health.diabetes/c/8rx9Xcb8UKQ/m/NQc3qBluAwAJ

    First off, Islit (Insulinitis, near-total to total loss of
    endogenous insulin), the condition I've had for over
    61 years (since age 5) requires exogenous insulin
    to try to stay alive.

    Did you read the book I mentioned, "The Diabetes Code"? It is a short
    book. Read it and come back here.

    Your post about "CURE", that's scientifically re-
    futable. All the claims about so-called 'control',
    claims do not scientific evidence make, & your
    failure to note that Islit REQUIRES exogenous
    insulin to try to stay alive, an egregious error on
    your part.

    Jung / the book & for several decades Richard
    Bernstein promotes low carb diets, my reply
    refuted low carb diets (& all restrictive diets)
    due to their high failure rate / high health risk.
    Fans promote it but I dare you to find any scien-
    tific evidence that any other than a small minor- ...

    ... ity are able to stick with it for a long period
    of time (at least 3 years). And in case you don't
    know, Islit is a lifetime condition, Islit requires
    exogenous insulin, & for all the promotion of
    low carb diets supposedly being superior, it's
    all lip service with loads of claims, not science, ...

    ... not evidentially supported as long-lasting
    in anything other than a tiny minority &, not
    without its own health risks. Preventable Cel-
    losis is the -only- Disparate High Glucose Con-
    dition that has reversibility possibilities & a
    wide range of diet / exercise lifestyles can ...

    ... help those with Preventable Cellosis, but
    due to the inherent difficulty of maintaining
    restrictive diets over a long period of time,
    the overwhelming majority of those who pre-
    vent or reverse Preventable Cellosis are un-
    able to make that last over the long term.

    ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ !

    Superior Clarifying Names first created and
    defined in 2010, trying to replace outdated
    anachronistic confusing misleading diabetes
    / diabetic / reactive hypoglycemia words and
    phrases:

    Diabetes Bubble / Diabetes Bubble Burst
    Exemplary! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    C.ure I.nsulinitis A.ssociation
    Outstanding! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    Sooner is Ideal! https://prohuman.net/glucoseanomaliesresearch.htm

    - - -

    The old confusing way which all-too-often
    involves folks using the diabetes / diabetic
    words without a clarifier:

    diabetes / diabetic without a clarifier,
    diabetes / diabetic guessing required https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg

    - - -

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ ! ~ !

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  • From Clutterfreak@21:1/5 to All on Sun Jan 9 11:18:13 2022
    On 1/8/2022 5:34 PM, _ wrote:
    Your post about "CURE", that's scientifically re-
    futable.


    Read the book.

    --
    This email has been checked for viruses by Avast antivirus software. https://www.avast.com/antivirus

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  • From _@21:1/5 to Clutterfreak on Tue Jan 11 13:25:30 2022
    On Sunday, January 9, 2022 at 11:18:16 AM UTC-6, Clutterfreak wrote:

    Read the book.

    Provide 1 iota of evidence that anyone
    with Insulinitis (Islit, near-total to total
    loss of endogenous insulin) is now free
    from using exogenous insulin & is alive
    after reading the book.

    Even the biggest promoter of a severe
    low carb diet, Richard Bernstein, who
    has had Islit for decades, he says that
    on his very low carb diet & his daily exer-
    cise routine he still has to dose exogen-
    ous insulin daily (I think he still uses ...

    ... injections), albeit smaller doses than
    he used prior to building his life around
    promoting a very low carb diet as the
    supposed be-all end-all diet for everyone
    with any Disparate High Glucose Condi-
    tion. I don't believe he ever addresses ...

    ... the percentage of people unable to
    or simply unwilling to stay on his diet,
    or the unhealthy side effects & risks of
    using his diet.

    Quality of life? Arguably, if food / drink
    doesn't cause you to get Cellosis or get
    too much weight, the delights of food /
    drink make for a much higher quality of
    life than does a highly restictive diet, the
    evidence is clear on that.

    ~~~

    While writing this, my Omnipod DASH
    pods which I ran out of & had to go to
    a new doctor to get & for reasons un-
    known, despite contacting my insurer
    & asking them to ship it to me over-
    night, they sent it Thursday & it took
    'til today to get here.

    After injections galore the past few
    days I'm overjoyed my pods have
    arrived.

    Injections, I used them for 58 years,
    been using continuous glucose moni-
    tors & Omnipod insulin pump the last
    8 years. Oddly enough, I had NPH in-
    sulin that expired in 2020 & was able
    to use it with my Fiasp insulin since ...

    ... I ran out of my pods (which cost
    $131 after insurance for a 3 month
    supply until one goes into the Medi-
    care 'donut hole', & last year when
    that happened, they cost $540 for a
    3 month supply).

    - - -

    As for having Islit for over 61 years,
    one hopeful sign (although the Islit
    individual in the following got the
    device that's in a 5 year trial because
    he had severe hypoglycemia probs,
    & I no longer have those probs thanks ...

    ... to my CGM & insulin pump) is in
    the following articles. Unfortunately,
    while encouraged / excited about the
    gentleman's claiming a cure, upon
    reading the article I discovered that ...

    ... "Shelton now takes 10 immunosup-
    pression pills every day to stop his im-
    mune system from damaging the new,
    healthy cells. People with organ trans-
    plants and stem cell transplants take
    the medicines to prevent transplant
    rejections":

    Very disppointed in that, it's arguably
    controversial to call something a cure
    when it requires immunosuppressants.
    Every other so-called cure that requires
    immunosuppression is rarely long-last-
    ing & often its removal of the require- ...

    ... ment to use exogenous insulin only
    lasts a limited time, with exogenous
    insulin re-implemented at different
    times for almost everyone.

    - - -
    December 9 2021

    Ohio man appears to be first in the
    world to be cured of Islit https://spectrumnews1.com/oh/columbus/news/2021/12/09/ohio-man-cured-of-type-1-diabetes--at-least-temporarily-
    - - -

    A northeast Ohio man has a whole new grasp
    on life while making medical history after the
    successes of participating in a clinical trial.

    ... Islit has controlled Brian Shelton’s life for
    more than 40 years. He was diagnosed at the
    age of 21.

    ... “I was a mail carrier for 30 years, and I would
    start walking up the street and then by the time
    I get to the end of the street I would pass out
    and start seizing right on somebody's front yard,
    and I couldn't get up,” Shelton said. “That would
    almost be a daily thing.”

    He’s had an ambulance called for him hundreds
    of times, and even passed out on his motorcycle
    and crashed into a wall in 2020.

    ... The life-changing clinical trial

    Earlier this year, they spotted a clinical trial by
    Vertex Pharmaceuticals for patients with Islit. In
    people with Islit, the body destroys the cells in the
    pancreas that create insulin.

    Vertex aims to address the underlying cause of
    Islit by developing therapies to potentially replace
    the insulin-producing cells that are destroyed. It's
    building on work started in the laboratory of Dr.
    Douglas Melton and at Semma Therapeutics,
    which was acquired by Vertex in 2019.

    In the trial, Vertex said the patient receives an in-
    fusion of new cells — grown from stem cells — that
    help to restore the body’s natural ability to create
    and regulate that insulin, essentially giving the body
    back the cells it’s lost.

    ... On June 29, Brian got an infusion of lab-grown
    stem cells. He received about half of the target
    dose. Shelton was the first human patient, which
    is why he wears a shirt that says “first in human.”

    ... “Even right from the start, it was different already,"
    "He wasn't up at 300 and 400 [blood sugar levels].
    The really big changes happened around the three-
    month mark. I mean, it was incredible. That was like
    I think the first time I told him in the morning, I said,
    ‘You do realize you've gone five days with not a drop ...

    ... of insulin.' And he, back in the day he was doing
    probably between 30 and 40 units a day.”

    ... Shelton’s body is now able to control its own insu-
    lin and blood sugar levels. He still wears the glucose
    monitor and checks it often during the day, but every
    time he reads the number he smiles.

    “It's one reason enough to just smile all day long,”
    Brian said. “And I understand why my doctor does
    because I'm part of him now. You know, he, he made
    me a full person. Let me put it that way. Yeah, gave
    me my life back.”

    ... he's like a whole new person and that it's changed
    his whole outlook.

    "He's happy," ... "He seems to have a clearer head.
    We're not always just thinking where's your number
    at? What do you need to eat? How much insulin do
    you need right now? A normal person is like between
    70 and maybe like 120 and that's a pretty wide range,
    but those are good numbers and now he is in that ...

    ... zone and it's unbelievable. It's just completely un-
    believable ... .”

    This trial is still in its beginning stage. It’s a five year
    study and will enroll as many as 17 patients with
    severe cases of Type 1 diabetes. Regardless, Islit
    experts across the nation are amazed.

    ... “We're all very, very excited about this progress
    because this gives us hope that using these stem
    cells and developing into islets, of which Dr. Melton
    was one of the leaders in this development, that it
    actually works in people and can provide, as we said,
    a functional cure for Islit.”

    [see above, he's on immunosuppressants, so this is
    *not* a cure, & even though he's had positive results
    thus far, the unknowable amount of time he'll be free
    of exogenous insulin & the risks of immunosuppres-
    sants prevent, in my opinion, this from being legiti-
    mately called a cure for Islit. (opinions may differ)]

    - - -
    A Safety, Tolerability, and Efficacy Study
    of VX-880 in Participants With Islit https://clinicaltrials.gov/ct2/show/NCT04786262?term=VX-880&draw=2&rank=1
    - - -

    Sponsor:
    Vertex Pharmaceuticals Incorporated

    Official Title: A Phase 1/2 Study to Evaluate the
    Safety, Tolerability, and Efficacy of VX-880 in
    Subjects Who Have Islit With Impaired Hypo-
    glycemic Awareness and Severe Hypoglycemia

    Actual Study Start Date : March 29, 2021

    Estimated Primary Completion Date : January 2024
    Estimated Study Completion Date : January 2028

    * - * - * - * - * - * - * - * - * - * - * - * - * - * - * - * - * - *

    For clarity about the -7- Disparate High Glucose
    Conditions (DHGCs) with -85- specific types, refer
    to the following:
    https://prohuman.net/diabetesbubblediabetesbubbleburst.htm https://prohuman.net/pix2/diabetesbubblediabetesbubblebursttitle.jpg https://prohuman.net/pix2/diabetesreactivehypoglycemiaoldnamesnewnames.jpg https://prohuman.net/pix2/oldnamesnewimprovednames.jpg

    Also, -6- specific types of a mostly non-glucose
    anomaly Insipidus -and- -21- specific types of
    Hypoglycemia Uncaused by Treatments for
    High Glucose (Hut) are fully explained at the
    following, beauteous bountiful Knowledge &
    Power:

    Everything You Ever Wanted to Know about
    DHGCs, Insipidus, & Hut, but were afraid to
    ask (or due to diabetes confusion, not knowing
    enough to ask):
    https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    - - -

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    * - * - * - * - * - * - * - * - * - * - * - * - * - * - * - * - * - *

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  • From Clutterfreak@21:1/5 to All on Tue Jan 11 20:19:28 2022
    On 1/11/2022 3:25 PM, _ wrote:
    Provide 1 iota of evidence


    The book provides it, not me.

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  • From Clutterfreak@21:1/5 to Clutterfreak on Thu Jan 27 11:46:27 2022
    On 1/11/2022 8:19 PM, Clutterfreak wrote:
    On 1/11/2022 3:25 PM, _ wrote:
    Provide 1 iota of evidence


    The book provides it, not me.



    If you have read the book I'd be interested to know your opinion of it.

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