Teens who use cannabis frequently more likely to have premature baby


Date:
August 19, 2021
Source:
University of Bristol
Summary:
Teenagers who use cannabis frequently may be more likely to have
children born preterm, when they become parents up to twenty years
later, finds a new study. The research repeatedly assessed 665
participants in a general population cohort on their tobacco and
cannabis use between ages 14 to 29 years, before pregnancy.



FULL STORY ========================================================================== Teenagers who use cannabis frequently may be more likely to have children
born preterm, when they become parents up to twenty years later, finds a
new University of Bristol-led study. The research, published in Scientific Reports, repeatedly assessed 665 participants in a general population
cohort on their tobacco and cannabis use between ages 14 to 29 years,
before pregnancy.


==========================================================================
The study, led by academics at the University of Bristol in collaboration
with the Murdoch Children's Research Institute in Australia, is the
first to identify that frequent adolescent cannabis use may also carry intergenerational risks Maternal tobacco or cannabis use in pregnancy is
linked to babies being born preterm and having low birth weight, raising
the risks for health problems in these babies. Substance use in pregnancy
tends to be a continuation of use that started before pregnancy, raising a question of whether use in pregnancy or before could be associated with a baby's early growth. The collaborative research team used the prospective cohort from the Australian Victorian Adolescent Health Cohort Study
(VAHCS) and Victorian Intergenerational Health Cohort Study (VIHCS),
with parents recruited to the study when they were in secondary school
and followed up until they started having children in their late 20s
and 30s; their children were then recruited into a new study.

The researchers found babies born to parents (aged 29 and over) who had
used cannabis every day for a period of time between the ages of 15-17
were estimated to be considerably more likely to be born preterm or to
have a low birth weight, when compared to babies born to parents who
hadn't used cannabis as teenagers. This effect was limited to people
using cannabis at the highest levels of frequency.

The findings are the results of a 20-year prospective study, following
parents from their teenage years into their 30s, which found that 20
per cent of all preterm births to study participants occurred in parents
who had used cannabis daily during their teenage years.

Dr Lindsey Hines, Research Fellow in Bristol Medical School: Population
Health Sciences (PHS) at the University of Bristol, said: "Cannabis is
the most commonly used illicit drug amongst teenagers. There is already evidence that frequent adolescent cannabis use increases the risks for
poor mental health, but our results indicate there may be further effects
that individuals may not anticipate.

"As regulations around legal use liberalise, there is a possibility
that adolescent use may increase in some countries. These findings
provide additional motivation for ensuring that policy changes do not
lead to greater adolescent use." George Patton, Professorial Fellow in Adolescent Health Research with the University of Melbourne and Murdoch Children's Research Institute, added: "The more we study heavy cannabis
use in the teens, the more problematic it looks.

Given growing political and industry drivers for legalisation of use,
there is a pressing need for bigger and better research into understanding harms arising from heavy adolescent use." This is the first study to
use a prospective cohort to explore associations between pre-conception substance use and birth outcomes, and the findings need to be tested
in other samples. Given the study's participants were both mothers or
fathers of the babies and that heavy teenage use is most common in boys,
these findings are particularly important for males.

Further research is needed to compare outcomes for men and women, as
well as to understand the biological mechanisms or social conditions
that might drive these associations.

========================================================================== Story Source: Materials provided by University_of_Bristol. Note: Content
may be edited for style and length.


========================================================================== Journal Reference:
1. Lindsey A. Hines, Elizabeth A. Spry, Margarita Moreno-Betancur,
Hanafi
Mohamad Husin, Denise Becker, Melissa Middleton, Jeffrey M. Craig,
Lex W.

Doyle, Craig A. Olsson, George Patton. Cannabis and tobacco use
prior to pregnancy and subsequent offspring birth outcomes: a
20-year intergenerational prospective cohort study. Scientific
Reports, 2021; 11 (1) DOI: 10.1038/s41598-021-95460-2 ==========================================================================

Link to news story: https://www.sciencedaily.com/releases/2021/08/210819102752.htm

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