• New Covid variant detected at Texas A&M lab shows signs of antibody res

    From Ubiquitous@21:1/5 to All on Sun Apr 25 20:15:05 2021
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    Scientists at Texas A&M University's Global Health Research Complex say
    they've detected a new Covid-19 variant that shows signs of a more
    contagious strain that causes more severe illness and appears to be
    resistant to antibodies.

    The new variant, BV-1, named after its Brazos Valley origin, was found
    during Texas A&M's routine coronavirus screening via saliva sample in a
    young student who had mild cold-like symptoms. The student tested
    positive for Covid on March 5 and tested positive again on March 25,
    showing that the new strain may cause a longer infection in younger
    people. The student's symptoms resolved by April 2 and a third test on
    April 9 came back negative.

    Texas A&M scientists say that cell-culture based experiments from other
    labs have shown that several neutralizing antibodies had no effect in controlling other variants with the same genetic markers as BV-1.

    "We do not at present know the full significance of this variant, but
    it has a combination of mutations similar to other internationally
    notifiable variants of concern," said Texas A&M Chief Virologist Ben
    Neuman. "This variant combines genetic markers separately associated
    with rapid spread, severe disease and high resistance to neutralizing antibodies."

    The scientists also say they have submitted a paper on BV-1 to the
    Centers for Disease Control and Prevention in Atlanta to alert
    officials before further spread continues.

    The lab has identified many Covid mutations with through its genetic
    sequencing program, but Neuman said the genetic makeup of this strain
    is particularly concerning.

    "We have not detected any more instances of this variant," Neuman
    added. "We have not grown or tested this virus in any way. This
    announcement is based purely on the genetic sequence analysis done in
    the lab."

    Lots of U.S. labs only sequence severe Covid cases, but the Texas A&M
    lab is testing and sequencing asymptomatic students to catch dangerous
    strains early before they can cause serious illness.

    "Sequencing helps to provide an early warning system for new variants,"
    Neuman said. The scientists at the lab say they do not yet understand
    the full significance of BV-1, but believe the variant "highlights an
    important need for rigorous surveillance and genomic testing,"
    especially among young adults who are asymptomatic or show mild
    symptoms.

    Scientists at the lab say the new variant is related to the B.1.1.7
    strain out of the U.K., which current vaccines have been shown to be
    effective against. The related U.K. strain makes up a majority of
    variant infection in the U.S.

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