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In article <t1adk8$2tg3c$51@news.freedyn.de>
<governor.swill@gmail.com> wrote:

Very happy to see Swallwell fail after his immature ignorant behavior with a Chink whore spy.

Monkey Pox, right on time to give Democrats an excuse to cheat in the next election.

<https://images.livemint.com/img/2022/07/23/600x338/HEALTH- MONKEYPOX--2_1653826741580_1658592379404_1658592379404.JPG>

Many of the people infected in an international monkeypox
outbreak experienced a single lesion or sore in their mouth or
on their genitals, a departure from typical symptoms of the
virus that could lead to clinicians to misdiagnose monkeypox as
another sexually transmitted infection (STI).

That's one of the main takeaways from the New England Journal of
Medicine's (NEJM's) new international study of the current
outbreak, which is the largest case-study on the virus.

"This truly global case series has enabled doctors from 16
countries to share their extensive clinical experience and many
clinical photographs to help other doctors in places with fewer
cases. We have shown that the current international case
definitions need to be expanded to add symptoms that are not
currently included, such as sores in the mouth, on the anal
mucosa and single ulcers," said Chloe Orkin, PhD, of the Queen
Mary University of London, in a university press release.

13% required hospitalization
The study included clinical observations from 528 confirmed
infections at 43 sites from Apr 27 to Jun 24 of this year. The
median incubation period is 7 days in this outbreak, and the
median age of a case-patient was 38. No deaths occurred, but 70
patients (13%) required hospitalization.

In the study, authors share many patients are presenting to
clinics and hospitals for pain management or difficulty
swallowing. Single anal sores have been recorded in several
cases. One in 10 people had only a single skin lesion in the
genital area, and 15% had anal and/or rectal pain, a symptom not
typically seen in other monkeypox outbreaks.

A total of 98% of the cases documented were in gay or bisexual
men, and while monkeypox is not an STI, per se, the authors said
95% of transmissions documented occurred during sexual
relations. Seventy-five percent of case patients are white, and
41% are HIV-positive.

The authors of the study also reported that semen samples
collected showed large amounts of the virus, but they said more
research needs to be done to understand if semen can actually
transmit the virus.

Symptoms vary by sexual practice
In a second study, published as a Lancet preprint, similar
conclusions were made based on the clinical presentations of 181
monkeypox cases in Spain.

In that group, 91.7% of patients were men who have sex with men
(MSM), and detailed sexual history showed that those who
reported having anal-receptive intercourse had longer incubation
periods (8 vs 6 days) and higher rate of systemic symptoms
before the rash (62.0% vs 27.6%) and presented more frequently
with proctitis (32.9% vs 6.9%) than MSM who did not engage in
this type of sexual practice.

"Because of the variability of clinical presentations clinicians
should have a low threshold for suspicion of the disease," the
authors concluded. This report, unlike the NEJM study, has not
yet been peer reviewed.

CDC further eases use of Tpoxx
After several media outlets reported doctors were filling out
paperwork for 3 to 4 hours to prescribe the antiviral Tpoxx to
monkeypox patients, the Centers for Disease Control and
Prevention (CDC) announced further plans to streamline accessing
the drug, which must be obtained from the strategic national
stockpile and is only approved for use in smallpox cases.

Photos and samples of case-patients are no longer required, and
paperwork has been reduced to four forms, which can be returned
to the CDC after the treatment has been prescribed.

In a statement on the change to protocols, the Infectious
Diseases Society of America (IDSA) said, "The reduction in
paperwork and other documentation required to obtain treatment
is welcome news, and we anticipate it will expedite access to
treatment. However, more work remains to streamline and expand
access to treatment and to collect data to further inform
tecovirimat use."

The CDC is reporting 270 more monkeypox cases today from 46
states, raising the national total to 2,593.

In other US news, the White House has released their research
priorities for monkeypox. They include further understanding
transmission, modeling and forecasting, vaccine effectiveness,
and developing novel diagnostics—among others.

Madrid reports monkeypox in baby
Following a report yesterday of monkeypox in a child from
Amsterdam, a baby from Madrid has also been diagnosed as having
the virus.

The child is 7 months old and contracted the virus at home,
officials said. Both of his parents were infected; the baby and
the parents are isolating at home with mild illness.

Finally today, the European Medicines Agency has approved
monkeypox as an added indication for Bavarian Nordic's Imvanex
(Jynneos in the United States) smallpox vaccine.

https://www.cidrap.umn.edu/news-perspective/2022/07/largest- monkeypox-study-date-highlights-new-symptoms

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