February 24, 2021
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The string of studies with negative results disappoints Dr. Paul
Marik, who published those early dramatic claims. He's a critical care specialist at Eastern Virginia Medical School.

"Some people think the matter is dead," he says. "We would disagree."

Marik says his own more recent experience is that the treatment is
only effective if given very early in the course of the disease. Marik
says he now gives the infusions when people first show up in the
emergency room, and doesn't wait for the hours or sometimes days it
takes before someone ends up in the intensive care unit. And that's
where researchers have studied this treatment.

"This should really be an emergency department study, not in ICU
study," he says. "Once you've waited until they get to the ICU you've
missed the boat."

Conducting research in the emergency department is a challenge because
it's tricky to explain a study and to get permission in the midst of a
health crisis. Marik says researchers in Belgium are trying to do
that, though, with the regime he developed (which is sometimes called
HAT therapy, based on the first letters of the technical names of its components, hydrocortisone, ascorbic acid and thiamine).

In the meantime, doctors who have been using this treatment face a
decision. Should they keep offering it, given all these disappointing
results?


https://www.npr.org/sections/health-shots/2021/02/24/971000085/vitamin-c-fails-again-as-treatment-for-sepsis

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