• Knowing how malaria parasites persist

    From JAB@21:1/5 to All on Mon Oct 26 19:38:02 2020
    On Mon, 26 Oct 2020 20:00:55 -0400, RS Wood <rsw@therandymon.com>
    wrote:

    A medical friend
    said currently malaria is the thing currently putting the most
    evolutionary pressure on human beings at present.

    Ask him to consider what I posted. <https://www.sciencenews.org/article/malaria-parasite-mosquitoes-genetics-immune-system>

    These research findings, if valid, may change his and others
    perspective.

    RE: "Dramatic evolution within human genome may have been caused by
    malaria parasite." <https://www.sciencemag.org/news/2017/03/dramatic-evolution-within-human-genome-may-have-been-caused-malaria-parasite>

    Maybe malaria parasite changed...notice cite above says "may"

    Diving into specifics, from Sciencemag cite:

    "That's a bit mysterious because the disease caused by P. vixax is
    much less deadly than that caused by other Plasmodium strains, says
    David Serre, a microbiologist at the University of Maryland's
    Institute for Genome Science in Baltimore who wasn't involved with
    this work. "You get sick, you stay in bed for a few weeks, and most of
    the time you get better." One wouldn't expect such a powerful
    evolutionary response to a relatively benign disease, he notes."

    First article I cited noted,

    "During Africa's dry season, when mosquitoes are scarce, malaria
    parasites have a hard time spreading to new hosts. So the parasites
    hide out in the human body by keeping the cells they infect from
    clinging to blood vessels, researchers report October 26 in Nature
    Medicine. This way, infected cells get removed from circulation and
    parasite levels in the body remain low, making people less sick and
    allowing the parasite to persist undetected. "


    I don't know the specifics here, but those two cites above seem to be
    in conflict...need more specifics.

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  • From RS Wood@21:1/5 to RS Wood on Wed Oct 28 11:47:21 2020
    RS Wood <rsw@therandymon.com> writes:
    Interesting stuff. I've lived most of my life in malarial places, and
    watched a lot of poor people suffer mightily from it. A medical friend
    said currently malaria is the thing currently putting the most
    evolutionary pressure on human beings at present.

    ... other than our own stupidity, I'm sure. Hey, does it seem there are
    more storms this year? Nah. Couldn't be. Carry on shopping, people.

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  • From JAB@21:1/5 to All on Wed Oct 28 12:58:06 2020
    On Wed, 28 Oct 2020 11:47:21 -0400, RS Wood <rsw@therandymon.com>
    wrote:

    Hey, does it seem there are
    more storms this year?

    I'm not aware of this on Earth's poles...just lightening strikes..PS
    see slideshow in article.

    August 13, 2019

    Lightning struck near the North Pole 48 times. It's not normal.

    A warmer Arctic in general provided the fuel for lightning-producing thunderheads to move north.

    https://www.nationalgeographic.com/environment/2019/08/lightning-struck-near-north-pole-why-strange/

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