• More Health News! Healthy Biden Vs. Sickly Trump = Experts Say Fat Sick

    From tommy thorsen@21:1/5 to All on Fri Feb 11 22:18:19 2022
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    Special online feature to the Journal on Active Aging5DRAFTSeptember 2020
    • Donald Trump and Joe Biden come
    from family histories of exceptional
    longevity (e.g., familial longevity). As
    such, there is suggestive evidence that
    both candidates are likely to be “super
    agers”—a subgroup of people that
    maintain their mental and physical
    functioning into late life and tend to
    live longer than the average person
    their age.
    • Both candidates have a higher than
    average probability of surviving the
    next four years relative to other men
    their age (95.2% for Biden—average is
    82.2%; 90.3% for Trump—average is
    86.2%). The main force influencing
    these favorable survival estimates is
    familial longevity. Socioeconomic
    factors contributing to this conclusion
    are that both have access to excellent
    health care, high income, they are
    highly educated, and both are married.
    • Both candidates are expected to have
    higher than average healthspans
    relative to other men their age in the
    US (about 10 years more than
    average).
    • Biden is expected to outlive Trump,
    even though he is three years older.
    The reasons are that Biden has an
    exceptional health profile for a man
    his age (e.g., ideal Body Mass Index
    [BMI], physically active, few
    prescription medications, no
    identifiable lethal conditions, excellent
    cholesterol profile, low inflammation).
    He also has a family history of
    longevity. Trump also shares most of
    this profile, except his obesity and
    sedentary lifestyle work against his
    familial longevity history and his
    otherwise healthy biological profile.
    Trump’s risk factors are significant but
    modifiable—it is unknown whether
    he has adhered to lifestyle recom-
    mendations from his physicians.
    However, this is not a longevity
    competition—both have a high prob-
    ability of surviving a full term in office
    after the election.
    • Trump does face an elevated familial risk
    of late onset Alzheimer’s disease (AD)
    as this was a major contributor to his
    father’s death (died of pneumonia, a
    common immediate cause of death in AD
    patients); and he also faces an elevated risk
    of heart disease due to verified risk factors
    publicly revealed by his personal physician.
    • There is no evidence available in the public
    record to indicate that either candidate is
    facing a major cognitive functioning
    challenge—either now or during the next
    four years. Trump does face an elevated
    risk of Alzheimer’s disease due to a family
    history of the disease on his father’s side.
    It may be tempting to conclude that
    evidence of cognitive decline does not
    exist because extensive diagnostic assess-
    ments of cognitive functioning have
    not been completed, and if done, some-
    thing significant might be revealed.
    Presidential candidates are evaluated by
    their personal physicians in much the same
    way the rest of the population is assessed.
    Diagnostic tests of cognitive function are
    not done unless the physician suspects the
    presence of a problem or if requested, and
    even then, a dementia screening test like
    the one completed by Trump (Montreal
    Cognitive Assessment Test–MoCA) is
    done first. There is no single diagnostic
    test that can determine if someone has
    Alzheimer’s disease. The decision not to
    order an extended battery of medical,
    neuropsychological and other diagnostic
    tests during the candidates’ most recent
    physicals is evidence for an absence of
    issues involving cognitive functioning for
    both Biden and Trump. It is unclear what
    would occur if a candidate or sitting
    president refused to undergo a screening
    or diagnostic test—if recommended by
    their physician.
    • This review of inherited and acquired risk
    factors combined with an assessment of
    available medical records for both
    candidates is not a guarantee of an
    anticipated survival or health outcome.
    Risk factors for health, longevity and
    cognitive functioning are subject to
    modification in either direction by
    both candidates; random elements to
    aging make it difficult to generate
    forecasts with precision; and both
    candidates are subject to health risks
    due to Covid-19.* Nevertheless, the
    familial, and personal health and
    medical history information publicly
    available from both candidates tend to
    favor the projected outcomes discussed
    here.
    • Based on a personalized assessment that
    includes an evaluation of inherited
    and acquired risk factors for health and
    longevity from a demographic and
    actuarial perspective; and from inde-
    pendent reviews of publicly available
    medical record data on both candidates
    by three independent physicians with
    expertise in aging; it is our conclusion
    that chronological age is not a relevant
    factor for either candidate running for
    president of the United States. Both
    candidates face a lower than average risk
    of experiencing significant health or
    cognitive functioning challenges during
    the next four years.
    * Donald Trump has tested positive for
    Covid-19 as this article is in production.
    This diagnosis raises his immediate and
    long-term risk of death by an undeter-
    mined amount. If Trump is a super ager,
    it’s possible that the same factors that lead
    to decelerated aging, also offer added
    protection from the harmful effects of
    Covid-19 on his immune system. Initial
    evidence from centenarians infected with
    Covid-19 suggest that super agers weather
    this challenge quite effectively.
    Executive summary
    Special online feature to the Journal on Active Aging6DRAFTSeptember 2020 population. Needing help with at least
    one activity of daily living (ADL), such as
    bathing and dressing, defined disability.
    Healthspan corresponds to remaining life-
    span without disability. The metric of
    healthspan is a byproduct of decades of
    research by scientists across the globe with
    the goal of devising a summary measure of
    population health that combines mortality
    risk with non-fatal health conditions.
    Healthspan was first measured in the late
    1970s by Sullivan, and it is now a standard
    reporting metric by the Global Burden of
    Disease project, the World Health Organi-
    zation, and in thousands of research articles
    since first developed.16 Healthspan is a
    standardized reliable health metric that is
    reported annually for most countries.17
    Results
    Lifespan (independent of medical
    history)
    • Biden life expectancy estimate using a
    combined risk factor approach = 96.8
    years (average is 87.4 years)
    • Biden probability of surviving a four-
    year term as president = 95.2% (average
    is 82.2%)
    • Biden probability of surviving to age 85
    years = 66% (average is 61.2%)
    • Trump life expectancy estimate using a
    combined risk factor approach = 88.6
    years (average is 86.2 years)
    • Trump probability of surviving a second
    four-year term as president = 90.3%
    (average is 86.2%)
    • Trump probability of surviving to age
    85 years = 60% (average is 55.0%)
    Healthspan
    In an earlier assessment of healthspan for
    Biden and Trump,3 it was estimated that
    men in the U.S. that are Biden’s age have,
    on average, about 9 years of healthy life
    remaining while men in the U.S. that are
    Trump’s age have an average of 10.9 years of
    healthy life remaining. Those assessments
    were based on expectations for a white col-
    lege-educated subgroup of men, so they are
    consistent with what is expected for both
    candidates—which is an estimated
    healthspan that is higher than average.
    Since there is no reason to believe that ei-
    ther candidate has lost any of their activi-
    ties of daily living (ADLs) or instrumental
    activities of daily living (IADLs), there is
    no basis for adjusting these healthspan esti-
    mates. However, given the more favorable
    overall health profile of Biden relative to
    Trump, even in spite of being three years
    older, it is safe to assume that the projected
    healthspans of the two candidates are
    roughly equal at approximately 10 years.
    Both candidates are projected to have a
    healthspan that extends beyond the end of
    the next presidential term.
    Physician reviews
    (summary)
    Dr. Nir Barzilai
    Considering that over 90% of people over
    65 in the U.S. have more than two morbid-
    ities (obesity considered one), the available
    medical records reveal an excellent overall
    health status of Joe Biden—placing him in
    the top 10% of his birth cohort for older
    adults. His most challenging condition is
    his atrial fibrillation that seems stable and
    asymptomatic with treatment to prevent
    thrombosis. There is nothing in his medical
    record to suggest that he is at a higher than
    normal risk for cardiovascular diseases, can-
    cer, type 2 diabetes mellitus, cognitive de-
    cline or death during a first term in office.
    The aneurysms he experienced in 1990 are
    no longer a significant health risk for him
    given his healthy survival during the past
    30 years. He’s on a limited number of pre-
    scription medications—implying a bet-
    ter-than-average set of health risks. The
    best piece of evidence in the medical record
    suggesting that Biden could be long-lived is
    the exceptional longevity of his parents;
    both of whom reached advanced ages for
    their birth cohort—with his father surviv-
    ing into his 80’s and mother into her 90s.
    Having long-lived parents has independent
    effects on the longevity of offspring, even
    independent of risk factors and physical
    dysfunction.18,19,20,21 For example, Alzhei-
    mer’s disease and type 2 diabetes mellitus
    can be significantly delayed for people
    with long-lived parents. Overall, based
    on Biden’s behavioral and medical risk
    profiles and his family history of exception-
    al longevity, there is a high probability
    Biden will survive with his physical and
    mental health intact through a first term in
    office.
    Based on the available data, Trump has two
    major documented health issues, obesity
    and a level of physical activity defined as
    sedentary. There is suggestive evidence that
    his dietary and sleep habits are unfavorable,
    but in the absence of definitive evidence for
    both of these covariates, it is assumed here
    that these are non-issues. Aside from obesi-
    ty and a lack of physical activity, the rest of
    the data available on Trump reveals excel-
    lent overall health prospects for a 74-year-
    old male in the U.S. relative to other men
    his age. Trump’s high LDL levels suggest a
    risk for cardiovascular disease, especially
    because these high levels are observed wSpecial online feature to the
    Journal on Active Aging8DRAFTSeptember 2020
    on cholesterol-reducing medication.
    Trump’s level of obesity places him at risk
    for type 2 diabetes mellitus. He has no
    known risks for cancer, cognitive decline or
    death during the next term. The best piece
    of evidence suggesting that Trump could be
    long-lived is the familial exceptional lon-
    gevity of his parents; both of whom
    reached advanced ages—with his father
    surviving into his 90s and mother into her
    late 80s. When familial longevity is consid-
    ered together with his behavioral risk pro-
    file, it is my conclusion that there is a high
    probability Trump would survive with his
    physical and mental health intact through a
    second term in office.
    Dr. Paola Rode
    Recognizing that there are constraints on
    publicly available medical records, available
    data suggest that both candidates have a
    high likelihood of surviving the next four
    years. Biden may have a slight longevity ad-
    vantage over Trump due to his lifestyle
    choices such as exercise and diet regimen as
    well as a Body Mass Index (BMI) within the
    normal range. Both candidates take less than
    the national average prescription medica-
    tions for men their age in the U.S. A Nation-
    al Center for Health Statistics investigation
    reported that approximately a third of per-
    sons over age 60 were on = 5 prescription
    medications in 2007–2008 (see detailed
    review below) As higher prescription medi-
    cation use can be associated with worse
    health status than those on less medication,
    the fact that they are both taking fewer med-
    ications than average makes them less vul-
    nerable. Both candidates have access to ex-
    cellent health care and are known to have a
    higher income which correlates with an in-
    creased life expectancy. This speaks to the
    fact that despite the age difference, both
    candidates are expected to survive a four-
    year term with their mental and physical
    capacities intact.
    Dr. Bradley Willcox
    Joe Biden is in excellent overall health for a
    77-year-old American male. His primary
    medical impairment is non-valvular atrial
    fibrillation (AF). This is a common age-as-
    sociated arrhythmia and does not appear to
    be due to underlying coronary artery dis-
    ease. He has never had any cardiovascular
    disease (CVD) complications attributable
    to AF, does not require rate or rhythm con-
    trol, and it is considered fairly benign. Case
    in point, he engages in vigorous physical
    activity that might overly stress a typical
    AF patient, without incident, and has done
    so most of his life. He has no clear evidence
    for CAD; he has a distant history of cere-
    bral aneurysms, which were successfully
    treated after discovery and are no longer a
    risk; he has no other major age-related dis-
    eases, and all physiological systems appear
    to be functioning well. Biden’s laboratory
    blood work is exceptional, particularly his
    metabolic/lipid profile (excellent cholester-
    ol, fasting blood sugar, hemoglobin A1C).
    His C-reactive protein (CRP) is very low,
    suggesting very low systemic inflammation,
    which is a major driver of the aging process
    known as “inflammaging”.22 His medica-
    tions are low-risk and minimal. His father
    and mother far outlived their birth cohort,
    living into their 80s and 90s, respectively.
    In addition to his family history of longevi-
    ty, Biden has a healthy BMI, and practices
    excellent health habits, particularly eating a
    healthy diet and vigorous exercise. This
    includes aerobic activity and strength train-
    ing, which are very important for healthy
    aging. Biden’s overall health profile suggests
    that he has a very high probability of sur-
    viving through his first term in office with
    his physical and cognitive function intact.
    Donald Trump’s overall health profile sug-
    gests that he has been quite healthy over
    the years, but he now is aging at an acceler-
    ated pace. He has clear evidence (on several
    Cardiac CT scans) for subclinical CAD,
    the leading cause of mortality in the U.S.,
    that has been worsening over the past de-
    cade. His otherwise lack of major disease
    and disability thus far may be largely genet-
    ic since his parents lived into their octoge-
    narian and nonagenarian years, although
    his father had Alzheimer’s disease for ap-
    proximately six years before his death.
    However, family history is not destiny (two
    of his brothers have died younger than ex-
    pected) and Trump’s poor lifestyle (un-
    healthy diet, lack of physical activity) may
    be catching up with him. This is evident
    from a worrisome increase in his coronary
    artery calcium (CAC) score over the past
    decade (2009–18), which has progressed
    from a low CAC score to a moderately
    high-risk score (approximately 7-fold in-
    creased risk for a major cardiovascular
    event [MI or sudden death] versus a score
    of zero23). On the positive side, other than
    obesity, he has a very good metabolic pro-
    file, he appears to be on few prescription
    medications for a man his age (less than a
    half-dozen low risk medications), appears
    to receive excellent medical care, practices
    some preventive health behaviors (e.g. takes
    a multivitamin, screening tests and immu-
    nizations appear up to date) and is married.
    In sum, based on these data, and assum-
    ing there is no further comorbidity in
    the limited medical records, he will likely
    live longer than a typical 74-year-old
    male.
    Overall, the medical records and/or public-
    ly available information suggest that Biden
    maintains an edge over Trump in terms of
    his chances of surviving, and surviving
    healthfully, over the next four years—in
    spite of the fact that Biden is three years
    older than Trump. However, both Biden
    and Trump are expected to survive the next
    presidential term with their mental and
    physical functioning intact

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