L‐DOPA Treatment Prevents Age-related Iron Accumulation, Mouse Study Finds
The study with that finding, “L-DOPA modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha-synuclein mouse models of Parkinson’s disease,” was published in the Journal of Neurochemistry.
Clioquinol is a compound that binds to iron molecules suppressing their (harmful) chemical activity. Studies demonstrate clioquinol is beneficial in animal models of three neurodegenerative disorders: Alzheimer’s disease, Parkinson’s disease and
Huntington’s disease.
Results revealed L-DOPA did not increase neurotoxicity in any of the mouse models and prevented age-related iron accumulation in the substantia nigra, much like clioquinol.
https://parkinsonsnewstoday.com/2019/02/14/l-dopa-treatment-prevents-age-related-iron-accumulation-mice/
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