Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease.
Cell Chem Biol. 2017 Oct 19;24(10):1192-1194.
doi: 10.1016/j.chembiol.2017.10.002.
Ayton S1, James SA1, Bush AI2.
Abstract
In this issue of Cell Chemical Biology, Telling et al. (2017) apply advanced X-ray microscopy techniques to reveal magnetite iron species in plaques from a mouse model of Alzheimer's disease. The characterization of abnormal iron chemistry in the disease
model highlights the potential for iron to combine with the β-amyloid peptide and accelerate the disease process.
Copyright © 2017 Elsevier Ltd. All rights reserved.
PMID: 29053948 DOI: 10.1016/j.chembiol.2017.10.002
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