• Iron In Periodontitis

    From ironjustice@21:1/5 to All on Thu Dec 9 00:45:35 2021
    High serum iron markers are associated with periodontitis in postmenopausal women: a population-based study (NHANES III)
    Susilena Arouche Costa 1, Cecilia Claudia Costa Ribeiro 2, Ana Regina Oliveira Moreira 3, Soraia de Fátima Carvalho Souza 4
    J Clin Periodontol
    . 2021 Dec 8. doi: 10.1111/jcpe.13580.\

    Aim: To investigate the association between increased serum markers of iron (ferritin and transferrin saturation) and the severity and extent of periodontitis in postmenopausal women.

    Methods: Data from 982 postmenopausal women participating in NHANES III were analyzed. Exposures were high ferritin (≥ 300 μg/mL) and transferrin saturation (≥45%). The primary outcome was moderate/severe periodontitis defined according to Centers
    for Disease Control and Prevention and the American Academy of Periodontology. The extent of periodontitis was also assessed as outcome: proportion of sites affected by clinical attachment loss ≥4 mm and probing depth ≥ 4 mm. Crude and adjusted
    Prevalence Ratio (PR) and Mean Ratio (MR) were estimated using Poisson Regression.

    Results: The prevalence of moderate/severe periodontitis was 27.56%. High ferritin was associated with moderate/severe periodontitis in the crude (PR 1.55, p = 0.018) and in the final adjusted model (PR 1.53, p = 0.008). High ferritin and transferrin
    saturation levels were associated with a higher proportion of sites with clinical attachment loss ≥4 mm (p < 0.05).

    Conclusion: The increasing serum iron markers seem to contribute to periodontitis severity and extent in postmenopausal women.

    PMID: 34879443 DOI: 10.1111/jcpe.13580

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