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  • Get to know the Devil

    From Taka@21:1/5 to All on Sat Mar 31 09:41:51 2018
    In fact, did you know that the ibuprofen, Advil, Alleve and other NSAIDs are merely nullifying the actions of arachidonic acid in your body? That's right - when arachidonic acid is released from membranes in your body, it triggers the COX enzyme which
    ramps up inflammation. All these NSAIDs do is inhibit this COX enzyme, thus lowering your body's inflammatory response and reaction to AA.

    MORE: http://www.peaktestosterone.com/Arachidonic_Acid_Dangers.aspx

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  • From Taka@21:1/5 to All on Sat Mar 31 09:43:01 2018
    The relationship between various concentrations of the male sex steroid, testosterone and the formation of radioactive prostaglandins (PGs) from 14C-arachidonic acid by human gingival homogenate has been investigated. There were statistically significant
    (combined) linear and quadratic tends between hormone treatment at concentrations of 10−9, 10−7, 10−5 and 10−3M and the amounts of PGF2a PGE2, PGD2 and 15-keto-PGE2 formed. The mean amount of each PG formed at the various concentrations of
    testosterone was statistically significantly less than the corresponding control level. The results indicate that testosterone, at the dose levels tested, is inhibitory to the cyclooxygenase pathway of arachidonic acid metabolism in gingiva.

    MORE: https://www.sciencedirect.com/science/article/pii/0262174682900695

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  • From Taka@21:1/5 to All on Sat Mar 31 09:33:19 2018
    Arachidonic acid signals for muscle protein sythesis via a COX-2 dependent pathway (suggesting prostaglandins are involved)[94] which is associated with increases in both prostaglandin E2 (PGE2) and PGF(2α),[94][95][96][97] although incubation with
    isolated PGE2 or PGF(2α) doesn't appear to fully replicate the hypertrophic effects of arachidonic acid.[94] PGE2 and PGF(2α) are also induced by exercise (specifically, a stretching of muscle cells in vitro[98]) and has been noted both in serum[99][
    100] and intramuscularly (four-fold, from 0.95+/-0.26ng/mL to 3.97+/-0.75ng/mL[101]) of exercising subjects, which are normalized within an hour after working out.[101] The ability of the stretch reflex to increase concentrations of PGE2 and PGF(2α)[98]
    may merely be due to stretching increasing the activity of COX2.[98][102]

    MORE: https://examine.com/supplements/arachidonic-acid/

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