On Saturday, 1 September 2007 11:51:53 UTC-7,
rs1...@yahoo.com wrote:
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2007 Jul; 25(3):211-44.
Ginkgo biloba leaf extract: biological, medicinal, and toxicological
effects.
Chan PC, Xia Q, Fu PP.
National Institute of Environmental Health Sciences, Research Triangle
Park, NC.
Ginkgo biloba leave extract is among the most widely sold herbal
dietary supplements in the United States. Its purported biological
effects include: scavenging free radical; lowering oxidative stress;
reducing neural damages, reducing platelets aggregation; anti-
inflammation; anti-tumor activities; and anti-aging. Clinically, it
has been prescribed to treat CNS disorders such as Alzheimer's disease
and cognitive deficits. It exerts allergy and changes in bleeding
time. While its mutagenicity or carcinogenic activity has not been
reported, its components, quercetin, kaempferol and rutin have been
shown to be genotoxic. There are no standards or guidelines regulating
the constituent components of Ginkgo biloba leave extract nor are
exposure limits imposed. Safety evaluation of Ginkgo biloba leave
extract is being conducted by the U.S. National Toxicology Program.
PMID: 17763047 [PubMed - in process]
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