• immortalisation of human genome

    From Ayaz Siddiqi@21:1/5 to All on Tue Jun 16 10:57:48 2020
    is it possible to immortalise human genome through cell cycle engineering of circularised dna?

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  • From Edward Montague@21:1/5 to Ayaz Siddiqi on Wed Jun 17 04:40:22 2020
    On Wednesday, June 17, 2020 at 5:57:49 AM UTC+12, Ayaz Siddiqi wrote:
    is it possible to immortalise human genome through cell cycle engineering of circularised dna?

    Good question.
    For awhile Geron Corporation were promoting Telomerase.

    Circular human dna seems like a great unknown.

    There are immortal species in the wild, like the Jellyfish and certain flatworms. Somehow they preserve
    the integrity of their dna.

    We humans, and many other species, have to contend
    with the mis regulation of cells that leads to a
    type of immortality that we want to avoid, or more
    importantly regulate through medication or possibly
    gene editing. We call these wayward cells, cancerous.
    Whether this will forever be an impediment to a
    healthy, immortal, human is a great unknown.

    An extreme piece of conjecture on my part; perhaps
    evolution is moving towards immortalizing higher
    organisms. I don't know of any evidence to support this notion.

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  • From Ayaz Siddiqi@21:1/5 to All on Fri Jul 24 08:56:48 2020
    G thanks

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