is it possible that their function is related to a distribution of protein side forms, like partially metabolized, passivated (Se at a sulfur containing amino acid), activity heightened (Like a keytone =O replacing a hydrogen at a C=C at phenyl group),
or just from partial enzymatic metabolism, this plurality of modified proteins that work almost as well, more effectively, or have different effects than the median form, likely the gene specified form, could be adjusted with drugs or physiology to
beneficially modulate their effects

Protein form distribution modifying drugs like longevity drugs
G coupled protein receptors' distributional forms, if they exist, could moderate, and amplify responsiveness as well as respond to completely different receptor activators, drugs that narrow or widen receptor form distributions (like normal distributions)
would be a new to me class of drugs with numerous new drug effects, moving a distribution towards responding to more molecules like they were insulin could be an antidiabetes drug, a keep tight around the antigen's receptor protein identity distribution
modifying drug could decrease autoimmune response, each cytoreceptor found that responds to a longevity heightening drug has a numeric distribution (like normal distribution) of proteins' versions like partial metabolites, passivated and higher activated
versions around it, and narrowing or widening that numeric distribution (tight or loose AMPK receptors, higher activation tropism AMPK receptors) heightens beneficial response (greater AMPK), or beneficially decreases response (ILGF-1, mTOR) as well as
at many other longevity effect modulating receptors that beneficially increase longevity

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