• Gene therapy drive for fish

    From Julia Amara@21:1/5 to All on Sun Jul 23 07:44:13 2023
    The hydrosorter could be a little like the top view of the internal crenellations of cardboard at about 14 mm width, with sensors tht can see through the 3d printed polymer or a transparent plastic plate on top of the hydrosorter, so one or more cameras
    can image the 1000 simultaneous fish for software processing; Notably things like THz imaging of the fish could work through the 3d printed polymer and the software could record things like organ size and skeletal density, and gill respiration rate, and
    heartrate, Also, light cameras placed at CAD optimized ports at the 3d printed hydrosorter are also possible, and general soft illumination provided through the 3D printed volume with external lighting;

    With positron emission tomography and radiolabelled physiochemicals like like radiolabelled longevity drugs that effect neurons, radiolabelled neurotransmitters, other tissues and molecules, as well as concentration and multiple measurements with time
    activity at the physiological tissues with the least vascularization, Then variations or shifts from the longevity drug molecule compared with untreated fish’ distribution of tissue activities and neural function can be gathered as data at a computer
    and mapped; it is also possible that noting the 25,000 groups of n=40 fish (1 million) screened each 2.8 hours, that a variety of longevity drug localization effects will be found, and finding out which chemical concentrates where has longevizing and
    wellness value.

    One use of the unique fish ID produced at something like a laser on GFP is the production of a library of frozen fish, possibly with detectable mRNA activity or things having other technology and drug development value, live clonability from the frozen
    fish, also detailed study of the 20-100 most efficacious longevity drugs’ per million fish characterized effect on things like cytoplasm, reproductive anatomy (sperm, eggs, livebearer growth areas), brain morphology, telomere length, cardiovascular
    fitness, cancer amount, and immune system effects;

    One area of longevity molecule research doable at fish at a hydrosorter, is the longevizing effects of reducing the amounts of some molecules from tissues or at circulation; It is possible the hydrosorter could be used to administer gill-breathable
    antigens (immunizations) against things like interleukins, sex hormones that are absent effects on secondary sex characteristics yet have cardiovascular risks or carcinogenic effects, liver enzyme saturating endogenous chemicals, mTOR activators, ILGF-1 (
    and similar molecules), endogenous telomere length reducing molecules, endogenous AMPK activity decreasing chemicals, possibly some versions of cortisol-like molecules circulating endogenously, physiochemicals that get upregulated when organisms miss
    sleep and could be deleterious (missing one night of sleep doubles likelihood of infection at a human); peptides (or proteins)that cause stress, possibly like deleterious versions of beneficial peptides (or proteins) that occupy beneficial receptors, but
    have zero or negative activity, keeping the beneficial forms of those peptides (or proteins) from reaching the receptors and providing benefit, various lipopolysaccharides that might reach the circulatory system from the GI tract, histamine, the
    physiological chemicals produced at gum disease that I read is like 20something to 48% active at causing cardiovascular disease, Any endogenous physiochemicals that cause heart rythms outside the wellness standard (although these are of course fish), as
    well as, noting that a combination of epithalon with thymosin causes four times less mortality during six years at humans, any chemicals that occupy epithalon and thymosin receptors causing those receptors to not function at preserving living function.

    A peltier enabled hydrosorter used at fish could also be used to develop cryogenic cryoprotectants to support human cryonic preservation and revival.

    Eugenics: The 3D printed hydrosorter could also be used to research a variety, notably a screenable library of 100,000 or a million freeze dried sperm preservatives to find those that produce motile egg-seeking sperm on rehydration, a technology that
    benefits eugenics, and can cause the manufacturing cents of a sperm emitting vaginal decal or also paper applicator vaginal canal 60 day attaching paint that continually emits genetically enhanced or also genetically optimized sperm to be about 11 cents
    a month, or 1.21 annually. Notably, 25,000 different drugs and preservatives can be screened on 40 sperm each 2.8 hours. Screening a billion freeze dried sperm revival with motility molecules, concentrations, and chemical treatment sequences is less
    than 120 days. Another technological from is a $4.14 5 gram polymer near cervix circlet that would gradually release 11 mg of motile previously freeze dried sperm every 24 hours for over a year, causing the likelihood of conception to be at 99% during
    the first 14.2 months of use among those persons capable of becoming pregnant

    Gene therapy and gene drive on fish: At fish in the wild it might be notably effective to gather wild fish in multiplenum nets, where the netting is coated with gene transfection gel, and then the fish released after a 1-14 minute interval of gene
    transfer to transfect what might be millions of fish with gene drive every 24 hours, with 100 days from one boat causing 100-200 million gene drive enabled fish to communicate gene drive to other fish in the ocean, providing benefits to fish like
    removing all nociception as well as decreasing nipping and fish social behaviors humans find ethically beneficial to obviate.

    Beauty genes that decrease risk of cancer: It is possible that female sex hormone receptors like estrogen receptors have a genetic 100 to 700% different amount of responsiveness to the same amount of circulating estrogen, progesterones, or other sex
    hormones, that the size and shape and optimizability of human female secondary sexual characteristics like breast size and shape and soft skin and even body form (like I have heard of banana shape and top heavy hourglass) could be enhanced with human
    germline genetic enhancement of estrogen receptor responsiveness to be at the 700% range, notably actual circulating estrogen could be the 2019 median amount or possibly shifted to endogenous estrogenic, progesteronic, or other sex hormone chemicals
    with just 10-50% of the cancer risk of 2019 AD median estrogen amounts or also particular estrogen molecule types, so this gives women and girls even more beautiful body form while reducing cancer risk 50-90%.

    There is a possibility that a technology that immunizes against background endogenous amounts of the chemicals produced when a human misses sleep reduces developing infectious disease, precluding, like with immunization, these chemicals, that are around
    even when a person gets a normal amount of sleep, could reduce the incidence of many, or most infectious disease; I perceive I read that missing a night of sleep doubles risk of infection, it is possible that is from the production of some chemical, or
    the activation of some receptors, it is possible that those chemicals, at different amounts, or receptors’ activation even when a person sleeps normally has some background amount, and that an immunization against those chemicals could reduce the
    amount of illness the amount of even persons that sleep normally get. it is also possible that germline genetic engineering as well as gene therapy could quantifiably reduce infectious illness of many kinds through causing less of the sleeplessness
    producing physiochemicals or receptor effects at persons that get normal amounts of sleep.

    New genes to optimize and enhance the human germline: I favor publishing all the material I have written, among those materials are notebooks; there is material written in notebooks as well as online material I have published favoring enhancing as well
    as optimizing the human germline, that enhancement as well as optimization can be the result of engineering completely new genes as well as enhancing or optimizing combinations of genes that already exist during 2019AD.

    Raed that during 2019AD pediatricians recommended that babies not sleep with anything in their cribs other than a sheet, perhaps this will improve but until it does, it is possible a flocked sheet with extrasoft flocked patterns on it, like velour
    macroscopic swirls could be a variation that the baby actually likes feeling the variations of, and where the baby like might moving over towards might be a beneficial enjoyed thing to put on baby sheets






    engineering, chemistry, computer ic, computer fab, longevity, longevity technology, treon, treon verdery, physics, lasers, laser, emiconductor, dimension, math, IT, IL, pattern resonance, time travel, chronotechnology, circile, eric the circle, cartoon,
    healthspan, youthspan, cpi, manufacturing, fiscal, money, software, petroleum, archive at deviantart com user treonsebastia

    All technologies, ideas, and inventions of Treon Sebastian Verdery are public domain at JUly 8,2023AD and previously, as well as after that date

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