Emotionally enjoyable surprise that might also have: cognitive interest, fascination, apperance or sensation benefit, from my 2019 AD initial perception is something babies and children both experience, might actually like, and at least at some humans,
might even seek. Quantitative psychologists could measure the enjoyability and benefits of benevolent surprise, like a hug just because, a toy that complements a toy that is already being played with, a beneficial brief change to schedule possibly one
day off from school to combine a amusement park visit with a 1 hour commercial math tutor visit might be measurable as causing enjoyment while actually raising school achievement and knowledge scores; If there are specific surpise actions quantitatively
measured as having benefit to babies and children these could be learned and propagated at the people with babies or also children. at 2019 AD surprise had a “know it when I see it definitionl space” Research could identify trend groups of
beneficial surprise based on measurably beneficiallness, like it might be found that hugs when given completely separately from bedtime, reuniting, consolation, or perhaps a measurable build up of lovingness communication, could be measured at 97/100
occurences experienced as enjoyable, and the slight surprise of the action also felt as enjoyable. It might be that new directions of beneficial anjoyable surprise are found.

Humans enjoy many things among them cognitive activities; it is possible that aesthetic scientists might find and measure the benefits of aesthically beneficial surprise, like a beautiful person giving away miniature sculptures, or even 3D printed
gorgeous candy, Or an actually-open-all-year one month duration at each location automatically relocating art gallery, or artmobile (like bookmobile), that appears in a new area of town (and pragmatically, perhaps gives away free food to heighten
spontaneous visitor visits in the new location hundreds of percent).

Alternately, at some cities of sufficient size, the art gallery could be like pop-up additional seating, full of art gallery content, at restaurants that are so busy as to be full some of the time, this causes more people to enjoy what it is at the
restaurant that is causing the popularity while also enjoying the aesthetic suprise and benefit of dining in an art gallery.



or a landscaped or architectural environment being augmented with quantitatively measurably as beneficial from aesthetic effect, surprise like a more-amazing-than-phone-camera instantly available at the lendscaped or architectural environment that
permits people to feel and experience the aesthetic benefit of the landscaping or architecture more, from feeling and composing with the camera as compared with just wlking through the environment. Measuring the surprise could just be the “hey
unattended zero-check-in cameras that’s fun. They say “see it fresh” on them too”



Talented scout, high surviving business economically self supporting, commercial establishment location finder. If some walk and drive-by traffic driven kind of consumer enterprise is at the number 1 item at list of highest likelihood of breaking even
or making money, a surival functional business, then that kind of enterprise could be placed in any screened commercial real estate to gauge the effectiveness of placing a different higher profitability or proprieter satisfaction and ethical values
immanentization business in the same location; Measurments at the number one surviving business like visitor numbers, receipts, AI analysis of video data like appearence frequency like Women, wealthy garments, age demographics, happiness and readiness-to-
spend body language correlates, with this data both at the business, and also as camera-based data from the street outside, as well as images of vehicles at the parking area. Also shared interaction with the clients at near area business



This could be made into a regularized, math business analytics supported way of improving site screening and location. With the survivability advantage that keeps the measurment-doing business open, the number of person visits, duration, inventory change
data, and particularly valuable things like AI processed analysis of appearence frequency like Women, wealthy garments, age demographics, happiness and readiness-to-spend body language correlates, both at the business, and as camera-based data from the
street outside, as well as images of vehicles at the parking area, are made available at any data-interval (months or even years) from locatiing a number one survivability business.



Interestingly this could be costless to the person seeking location optimization guidance. So even a person thinking of putting in a dollar store could contact the “we test your location using a number one business with zero fees, you just arrange the
real estate. So the person’s company initially only risks the lease, which is less than the financial risk of the full business without location testing. (fresh to me is that this is similar to a: you own a commercially successful franchise (business)
even if there is financial defualt (with the location screening company) producing effect; if it does not go right, then you just have this highly likely to be functioning business, at that location, with the real estate functionalized) Specific region
and city versions of the number one surviveable business could be found to make this more functional.



What happens when it does not work? Like you open a dollar store in a winter ski town, and 3/4 a year emptiness is absent supporting even a number one most survivable business? The number of visits, duration, inventory change data, and things like AI
processed analysis of appearence frequency (Women, wealthy garments, age demographics, happiness and readiness-to-spend body language correlates) are still useable when the person is figuring out a ski-town functional business.



What kind of business causes the most improvement in subjective well being? This is experience as well as content based; a ranked database of these would include both certificate colleges (lifetime benefit) as well as amusement parks (immediate fun), so
it does at least suggest a 97-99th percentile happiness improvement business list group.



Longevity technology: I read that it is possible to turn on a cytomembrane located receptor with an immunization that recognizes a piece of the protein that the entire receptor is made out of https://www.semanticscholar.org/paper/Creating-leptin-like-
biofunctions-by-active-against-Lei-Wu/0e00fcd3f6e8e89dc0d2fa1ef2fa9c105440c8a3 ; are there any receptors that if turned on more create greater longevity and wellness? Epitalon and thymosin receptors could be an application as the combination of
epithalon with thymosin administered as drugs causes people to be four times less likely to be dead after 6 years, so an oral vaccine that installs endogenous On-action state of epithalon and thymosin receptors could be a longevity and wellness producing
immunization. It could be that giving this to children, notably when they are receiving childhood immunizations could provide lifetime benefit as will as increasing lifespan. People caring for their children causes children to receive a number of
immunizations simultaneously as children, placing longevity and wellness causing immunizations at this group produces greater longevity and wellness, that also supports the communication to parents that the immunization group applications are beneficial
to their children.



hint of how to make an immunization is described at ,”immunization, emulsions of PBS solution of a KLH-peptide conjugate (Sigma-Aldrich, USA) mixed with either CFA or IFA (the 1st or the 2nd immunization, respectively; Disco laboratories, USA) were
subcutaneously (s.c.) injected at a dose of 100 μg of the protein per mouse in the proximal part of its tail (in control groups, vehicle was used). Starting on Day 53 mice were trained in a Morris water maze: Initially, in 3 trials, to reach a visible
saving platform and then, in 4 daily trials for 5 days, with an invisible (submerged) platform. Finally, on Day 58, a memory test followed by the brain preparation for further histological and histoimmunochemical analysis was performed. The serum samples
for the antibody titer estimation were taken from the eye vein on Day 52 and kept at –20°C for further analysis (see results in Table 1). As controls for the p75NTR fragments, KLH (Keyhole Limpet Hemocyanin) conjugate of SQDRHKQKIIAPAKQLL peptide
corresponding to the fragment of 197–213 of VP1 protein from foot-and-mouth disease virus (VP1), and KLH along were used.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942728/





Making immunizations: Keyhole limpet hemanocyanin (KLH) is on alibaba at $4.84/mg, or 10 mg for $48.40 At 100ug per mouse that is .28 mg of KLH per human 70Kg mass, or about $1.73 to immunize a human; it is possible that this material is much more
effective than CuSO4 or NiSO4 as an immune response effector; Oral KLH has published effect, I think insufflated (snorted) KLH may as well. There is a KLH produced immune response described at a paper online that uses 100 ug/ml of KLH with peptides to
immunize against things.



Just combining KLH with testosterone and snorting it or enteric capsule taking it could immunize against testosterone.



snorting something can reduce an immune response, “Intranasal immunization with phosphorylcholine (PC) is known to reduce immunoglobulin (Ig)E production.” That brings up the possibility of reducing an immune response, thus causing some thing, like
a biochemical, to have a greater physiological amount, then find which things that when there are more of them have a beneficial longevity effect. I think I read there are autoimmune illnesses, like allergies, perhaps people with atopic dermatitis could
be medicated with phosphorylcholine combined with dermatocyte proteins to reduce their immune responses to their own body, reducing illness and making people feel better.



lookup: the different: immunize to switch-on as compared with immunized to cease activity at a receptor, as well as immunize to have the receptor containing cyte macrophage-eaten antibody forms and antigens



Noting the cytes that senolytics terminate, are there any other entire human somatic cells that if they were absent, their absence would be beneficial to people? Possibly “rogue macrophages”, the cytes at atherosclerosis plaque bulk areas, or
possibly some variety of connective tissue repair cytes that are less optimal than some other coproduced tissue repair cytes would, if immunized against reduce scarring, and beneficial at the entire body, make more optimal repairs.



Are there stem cells that only differentiate into things that are nonoptimal for people? Immunizing against those stem cells would cause less of those things. Possibilities are arterial plaque blob cytes, kidney (connective tissue fiberization cytes)
and lung (COPD) fiberization, or lung flexibility modifying cytes, other possibilities.



So, if they find out some kind of cyte makes expansion and breathe-out effectiveness reducing fiberness and other tissue, then on first detection of COPD, those kind of cytes could be immunized against, causing gradual chronological lung change to be
absent any of the increase in cells that nonoptimally effect lung flexibility, this could be an immunization that reduces COPD symptoms, possibly increases lung tidal volume, and might beneficially affect lifespan and wellness.



Pneumonia preventing immunization: It is also possible that an immunization at childhood or 49 could cause macrophage removel of entire cyte types, also, immunogenic (immunization) turning of chemoreceptors all, or more on, or all or more off, or could
produce better lung tissue morphology amount at those 49-172 (or older); Pulmonary cytes with more flexibility (less fiberous tissue), various mucous types or fluidity, or causing a cytomemebrane chemoreceptor effect,possibily through antigen
basedimmunization that causes more ciliary motion from causing the ciliary motion change that a beneficial drug would cause, from immunizing to glom all or part of a chemorecptor protein could be possible.



More pulmonary ciliary activity could reduce many kinds of illness, so gene therapy, possibly inhaled, that localizes the production of some ciliary characteristic or ciliary stimulant to just the lung tissue could heighten ciliary action withut
effecting the rest of the body.



Bile acids are published as increasing some wellness things. Probiotics genetically engineered to make bile acids could be physiologically beneficial to humans.



The brain has cilia. “ciliated cells of sinuses, brain ventricle ependyma” What is the effect of stimulating that action of these cilia or making it the amount at

children? Is there an optimal and optimizable amount?

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