Longevity technology: Halogenation like fluorination causes corticosteroids to be 1000 times more active at a particular mg of dose, ethynylization causes progestins and estrogens to go from .3mg to .03 mg, although I perceive, or perhaps just would like
it to be more orders of magnitude; simultaneously halogenating and ethynylizing longevity drugs like rapamycin, royalactin, 10HDA, acarbose, metformin and others could give them 100-10,000 times the effect per mg dose; this causes 200 year duration
depot injections to be, at rapamycin’s 89 mg/24 hours to be .0089 mg/24 hours, the 60% longevity increase at mice could be thought of as 90 days or near 14 years of continuous human dosing as a ratio fraction. 14 years of halogenated ethynylized
rapamycin at .0089/mg/24 hours is 1093 mg, or about a one gram, one dose depot injection that could make humans live 60% longer. Another thing that could create even eentsier dosage mg is linking the halogenated ethynylized rapamycin to a capillary
epithelial membrane transport peptide or protein; it is possible that this modifies the dose to produce the longevity function to be .5 to .1 the dose of nontransport moeity halogenated ethynylized rapamycin, that causes the 60% longevity dose to be a
depot injection of 547 mg to 54.7 mg. It is possible a variety of other longevity drugs as well as new longevity drugs would benefit from the halogenation and ethynylization and membrane transport moeity construction.



I read that epithalon (AEDG peptide) combined with thymosin peptide causes people to be about 4 times less likely to be dead after 6 years; I also read that during the 20th century infectious disease was the biggest cause of mortality among people under
five years of age; administering epthalon with thymosin to babies, at the same interval as caused the four times reduction of mortality, or utilizing a one dose depot injection, or a one dose gene therapy version that produces epithalon as well as
thymosin endogenously, or also a germline modification could remove the leading cause of mortality amongst children under five.



could an enteric capsule full of liposomes, perhaps similar to a fish oil gel cap be even more effective than liposomes or an enteric capsule on it own? If so, greater effect at few mg could be an effect.



Does epithalon coadministered with thymosin’s near four times reduction of mortality have any effect on malaria, either transmission receptivity or mortality? Bill Gates might value that; administered as an enteric pill for three to fourteen doses once
is similar to the online description of epithalon with thymosin dosing; it is possible an enteric gel cap full of liposomes could keep the peptides functional while making mg/dose more effective.



I do not know if liposomes can transport long lasting palmitate linked to active drug molecules so that the oily kind of thick material still functions as a depot drug even though it is transported via the GI tract; if a liposomal depot drug is possible
then epithalon with thymosin as a palmitate could be a 1-3 month functional continuous dose, which is similar to what I read about online (2 weeks of daily doses, 6 months or 365 days apart); that permits an oral capsule one or twice a year drug that
reduces risk of mortality about four times.



I read near 2019 AD numbers on things that cused mortality, changing those things causes more people to be alive, longer; I read poisoning causes near 40,000 mortality occurences annually, more than motor vehicle accidents; What I read mentioned that
people taking a different than optimal dose, of a drug different than what they thought they were taking was one of the causes of poisoning: At the bathroom, or wherever people take pills, a computer with a camera could watch people take their pills
then alert them if they were taking a different than usual amount of a pill, among the possibilities are a dish the person puts their pills into before taking them, or a computer scanned vanity surface (likely based on a surface existing at their
dwelling), or a computer, perhaps with artificial intelligence like deep learning, simply watching them grab pill containers, put some in the hand and swallow them; The computer then tells them before thay take the dose that it is an error quantity, or,
if the dose has already been taken, audibly urge them to visit an affordable within-the-hour treatment medical service, at 2019 AD one description of these was “urgent care”; the computer could also alert relatives or audibly activate a dwelling
partner’s phone and tell the dwelling partner about the occurence if they had greater than a .05% chance of a mortality event or other lasting physiological nonoptimality.



I read that near 2019 AD poisoning caused more mortality than vehicle accidents; Software, possibly artificial intelligence like deep learning has cameras at the entire dwelling and scans the entire dwelling for poison hazards then suggests changes like
moving potentially hazardous things to places like the garage, or even suggests using a pharmacy that puts pills in noticeably different shaped and patterned containers so there is less risk of medication error; a more affordable version that might
function globally is to have the person video video their entire dwelling, upload the video to the internet cloud, and have a particularly effective piece of software or artifical intelligence figure out suggested changes; at the developed world, health
maintenance organizations, or also insurers might make money providing this as a complimentary service, even paying $ when the person modifies their poisoning risk.



Another thing I read about online is that functional suicide attempts couse near 40,000 mortality events a year. It is possible at a dwelling with non-internet cameras, perhaps connected with something like bluetooth, and software that interprets the
video they record could find patterns of things like movement slowness, bedded hours, food preparation/eating changes that the software or artificial intelligence like deep learning AI computes as predictive of suicide; then communicate with the person
audibly, using quantitatively measured as reducing the quantity and effect of suicidal behaviors, perhaps saying things like “can I phone your sister?”; it is possible the software could do things like open a web browser tab with a suicide prevention
chat page on it as well; The software would calculate the amount of risk, and at the user’s adjustable option possibly alert the persons health maintenance organization so they could contact the person with opportunities to just show up or make an
actual appointment; a suicide prevention expert, or software quantitatively measured as being as effective as a human expert at preventing suicide could phone the person directly as well.



They could have multiple daycare rooms in an art museum where the children all have similar, as well as happy, big five personality test measurements; the daycare rooms at the art museum full of big five personality test happy children doing what they,
as children, do is an art exhibit; if it is popular then is could be a permanent exhibit; taking videos and photos is considered normal.



Something that acetylates mTOR genes would reduce mTOR activity which goes with greater longevity; along with a drug this could be a gene therapy as well as a germline gene modification.



Salicylate cause yeast to live near 400% longer; what genes does salicylate cause to be expressed or have less expression; drugs, germline gene modification as well as gene therapy that cause those genes to have greater expression or less expression, to
porduce greater longevity, could be a human longevity technology.



At a woman screening her own eggs to find those with the largest number of the genes she prefers to have at her child I think it is possible to find more babies per million to be born well, that benefits the progeny of the genetically screened babies as
well; That increase in the amount of well babies is another thing that attracts people planning a pregnancy, like potential parents, to screen and even construct the genetics of their children.



Is there a protocol that causes meiosis at stem cells? If such a protocol exists or can be made then that could be a way to produce one billion genetically heterogenous cells, such as eggs (oocytes) from a cheek swab from one person; screening those one
billion genetic variations finds the most optimal version of the person’s genetics to grow children with; the screening technologies could be new screening technologies as well as things like flow cytometry of mRNA color generating eggs (oocytes), or
mRNA color generating differentiated cells, utilizing color from benign molecules with a color response to particular mRNA, microfluidic arrays viewed in parallel with a camera, something novel like laser tractor beams that only move cytes of a
particular mRNA color that is produced to a side of the well to be gathered and utilized, or integrated circuit technology billion or trillion well arrays where each array semiconductor element has a color sensor integrated circuit element under each
well so each cell at the array, when producing color from its mRNA color production, uses the imaging semiconductor to describe the presence of a particular version of a particular gene; at the billion or trillion well array, that two to the 40th power
one per trillion stochastically produced cell (2^40) with the highest number of preferred gene version occurences is located, dedifferentiated, the stem cells utilized to make eggs (oocytes) or sperm; valued mRNAs could be things that make
neurotransmitters, neurotransmitter receptors, beneficial growth factor gene version for things like BDNF, longevity causing mTOR activity minimizers, AMPK activators, gene variations that direct greater kindness, greater beauty, greater intelligence,
also any known beneficial phenotypic morphology gene stimulators such as tallness, slimness, delicacy and attractiveness of female features, along with the new traits and themes from the test that links 97-99% of the trait, theme as well as ability to
particular versions of particular genes; two to the 40th power is about 1 trillion, so a trillion cell screening protocol (flow cytometry, laser tractor beams, integrated circuit technology trillion well wafer) can find a cell with 40 simultaneous
preferred genes from meiosis; that differentiated mRNA-measureable cell is then dedifferentiated and the stem cells that result are differentiated to make eggs (oocytes) or also sperm with all 40 preferred gene versions. The person, the person that
would like to be a parent, then combines the curated version of their genome with the curated version of their prtner’s genome or gametes from a sperm bank or gametes from previous genetic screening and concentrating at other people; A technology that
makes each of 300 gene variations specifiable utilizing the cheek swab of one person is to have 300 separate wells of differentiated cells, then do mRNA color sorting, then at each of the 300 array locations dedifferentiate the sorted cells that each
have the preferred genetic version (of the two versions at each of the persons two sets of 23 chromosomes) to make stem cells, then differentiate to make egg (oocyte) and sperm at different wells of the 300 well array, then combine egg (oocyte) and
sperm, which causes the preferred gene versions to be at all the cells of the new balstocyst, then dedifferentiate the blastocyst cells to make a new egg (oocyte) or also sperm to combine with the egg (oocyte) or sperm produced from a different array
well; this cycle of making stem cells and gamete cells, and combining them with the eggs (oocytes) or sperm from other gene concentrated array wells repeated 300 times causes the preferred gene versions to accumulate; this can be utilized at many more
than 300 gene variants. I read that there might be 20,000 human genes, although there could be a higher number, so if a microfluidic 20,000 well cell structure can be produced that can microfluidically transport, cycle cells from egg (oocyte) and sperm,
to blastocyst, cycle different fluids that activate different mRNA production, as well as do mRNA color cellular concentration at differentiated cells, it is possible to imagine a laser ablating the cells at a 300 or 20,000 well system that are a color
that is absent the preferred gene variant, then a mass manufacturable microfluidic integrated circuit could be produced. Notably, a 5 megapixel camera sensor is about $1.49 online, so an integrated circuit technology MEMs or microfluidic technology
object with 20,000 array elements at the same Cm^2 area, combined with a published one million parallel element microfluidic array could plausibly be less than 8 hours earnings for a median USA person. So, for 8 hours earnings, the most favorable
version of an particular person’s genetics can be specified at their children.



Macroscopic technology version that is responsive to demand, and scalable: if macroscopic 96 well plates are used for: differentiated cell mRNA color sorting, mRNA color causing fluid cycling, gamete combination, dedifferentiation, differentiation to
eggs (oocytes) or sperm, then fluidic transport to another well at the plate with another other egg (oocyte) or sperm, dedifferention, differentiation, and fluidic transport again 20,000 times then every variation on every human gene is specifiable at a
macroscopic system, notably the 20,000: color screen, dedifferentiatiate, differentiate (eggs (oocytes) and sperm), mRNA color fluid cycle, fluid transport, gamete combination, dedifferentiation cycle can be done in complee parallel, making the length
of the process, and technological form of the mechanism, adjustable to optimize affordability and velocity in response to consumer demand.



At a 96 well plate, multiparallel machine, the microfluidics are much larger, can use 1-7 mm pumps, or even macroscopic pumps not on the plate, each well can contain millions of identical eggs (oocytes) or sperm per well, millions of balstocysts per well,
and only 677 plates are used if 20,000 seperate wells (near to covering the entire human genome) are utilized.



Notably, the macroscopic 96 well plate mechanism in parallel can provide ramp up based on the early, mid, and continuing, to 20,000 different gene preferences of people who want to be parents, If the mechanism’s capacity doubles every six months from
technology improvements, part of mechanism, or just a bunch of mechanisms at one location functioning with parallelism, with preparental consumer demand for more and better genetic specification options (creativity, musical ability, blue eyes, reduced
risk of cardiovascular disease, the 97-99% genetically predictable traits, themes and abilities), then a system that starts with fluidically cycling one 96 well plate can go from 96 specifiable gene variants to the 677 plates (20,000 genes) in 54 to 60
months of technology development of multiwell plate parallelism based on the ramping up of commercial value of giving prospective parents more, and more beneficial genetic options.



flow cytometry, microfluidics, or laser tractor beam sorting of differentiated cells makes it so the cells can be cyclically treated with different gene activating (mRNA expression causing) fluids and their mRNA colorized differently depending on which
of two versions (one version at each of the 23 chromosome groups, two to prefer one genetic variant of) is preferred; once found the genetically preferrred cells can be dedifferentiated to stem cells, then differentiated to make eggs (oocytes) or sperm
for use in fertilization to produce a baby with the person’s preferred genetics.



Using a cheek swab to get cells, then dedifferentiating these to make stem cells, then differentiating the stem cells to make eggs (oocytes) is able to produce a billion or a trillion eggs; at a flow cytometry mechanism, a microfluidic array, or an
integrated circuit technology array grid it is possible to place a variety of fluids on the eggs (oocytes) that cause different mRNAs to be produced at the oocyte, it is possible these mRNA describe the actual genetics of the oocyte, providing data about
the actual genes on the 23 chromosomes of the oocyte. Fluorophores or other color molecules that change color when a particular mRNA (and gene version) is there are also utilized; If that is functional then with a published flow cytometry machine that
processes 10 million cells a second, one billion oocytes would take 100 seconds; a trillion oocytes analyzed would take 27.8 hours, or an hour with 28 machines in parallel.



Making a psychology and ability test that is strongly linked to genetics: Finding those personality and ability traits with the strongest genetic determinants: The Minnesota multiphasic personality inventory was produced from mass screening a large
number of questions then winnowing those to a group of questions with high predictive validity; similarly a group of 100,000 questions, including nonverbal pattern match and sequence, could be administered as test groups of 40 questions to the hundreds
of thousands or potentially, millions of of persons using personal genomics websites like 23andme or others; Then the questions that predict genetics at 97-99% of occurences, and also accurately predict another previously unmeasured group’s genetics
and question responses are a source of things strongly predicted with genetics; the questions are then grouped into completely new themes, also known as traits, humans, that is persons, that is people, are likely to to perceive these themes like a vector,
a direction and a magnitude, with particular directions and magnitudes being more beneficial; people are then able to specify these genes on purpose at their children with 97-99% likeliness of producing that personality character, trait, as well as
themes along with those abilities they genetically specify.

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