Lithium can make c elegans live 35% longer, and humans that get more lithium in their water live longer, the Genetics of lithium absorption from food and water could be longevity genes, Lithium isotopes vary strongly in AMU with lithium six being about
14% different than lithium 7, they could see if these two comparatively common isotopes have different longevity effects for drug purposes

Lithium chloride containing charged micelles could localize delivery of lithium to different tissues and even endocytotic areas to find areas that most longevize when they get more lithium

If the epigenetics of newborns differ from the elderly then they could find out if setting the epigenetics of mice throughout their life to be that of newborns (or perhaps analogous to 9 year olds) causes greater longevity, based on that they could find
out which particular epigenetics matter to longevity to make longevity drugs as a longevity technology

CR causes greater longevity at yeast, if longevizing fungi, possibly reishii mushrooms are calorically restricted do they live longer, if they do they could compare the longevity effects of CRreishii to regular reishii on mice, if the CRreishii mice live
even longer than regular reishii mice then they could find which CRreishii chemicals are more abundant and test those chemicals as longevity drugs

Shared features of the epigenetics of human super centenarians are installed at mice, if they live longer then completely new epigenetic modifications from theory can be tried on the mice and if the mice live even longer then those completely new
epigenetic modifications can be made a part of the human epigenome, reversibly, in case people don't like any of the unplanned effects

Halomethionine as a longevity drug, decreasing methionine intake increases longevity, it is possible halogenated methionine or metric g methionine or some other chemical that is utilized where methionine goes could be dosed with regular food to
outcompete the methionine in the food so the methionine from food goes unabsorbed, aside from receptor effects methionine is a part of many proteins so a synthetic amino acid that looks a lot like methionine could work, I am under the impression that
there are things that transport methionine, down regulating those things with drugs or genetics could be a longevity technology, also there could already be an endogenous enzyme that gets rid of methionine, a methioninease, upregulating that with drugs
could be a longevity technology, a probiotics that eats methionine or exports a lot of methioninease could be a longevity probiotics

If there is not a known methioninease then one could be rapidly produced at a culture of the most successful probiotics where 90% of the food resource is methionine and a mutagen is present

Cr increases longevity, perhaps there is a save it for later (SIFL) proteomic activation network that gets activated, if there is a SIFL it is possible drugs could activate it without CR or other stressors

Nutrient depleted plasma, finding new things where if there are less of them, like calories and methionine, the organism has greater lifespan could possibly be found if plasma is mass fractionated into 1000 components or electrophoresized into 1000
components, the components dehydrated, mixed with insoluble material and fed to c elegans or daphnia, 2-3 96 well plates at an automated feeder could do it, the diet fed to each c elegans or daphnia well colony is missing 10 of the 1000 fractions, if any
of 100 sample groups had a strong longevity effect then they would do a separate run on that group of 10, to find the nutrient that when missing caused greater longevity, this could plausibly have found methionine, they could include 1/4 unfractionated
plasma at the food to ensure that if the chemical were essential yet deleterious the organisms would be partly supplied

An AFM tip like the kind used to position single atoms could move around single radioactive atoms like technetium and sometimes the atom would fission when the tip was directly on it, along with this being a new to me way to study radioactivity it could
be used to find out if anything effected radioactivity from recoil to atom charge changes, along with all kinds of known fields and forms like plasmonics they could advertise to find people who think they can make things glow or have other paranormal
abilities then ask them to perform it on the apparatus to find out if there was any difference

The genes that code whatever part of the pancreas that makes insulin could have longevity allele gene variations, copied into mice they could find the most longevizing version at the mice then look at humans' longevity at the most mouse longevizing human
alleles to verify that these are human longevity genes and alleles

I noticed watching erotic videos that women right before or at the very beginning of orgasm pulse the area of their buttocks about 2 inches to either side of the base of their vagina, a computer could visually monitor this and other body signs, perhaps
with THz imaging and then say "yeah" or "go" softly to let her partner know they should continue that action, there might be a male body profile that does this as well, the computer could say "him" and the partner could know to continue or to shift to
another activity

Longevity technology

Rb is in the same column as lithium on the periodic table, testing it for longevity effects on c elegans and at preexisting people could be beneficial

It might be possible to learn something from fingernail clippings and saliva from supercentenarians



Genetics of thoughts per minute 99th percentile of happiness and creativity, genetics, also thoughts per minute as a measure of nootropics

cell adhesion molecules and neurexins and neuroligans might hold synpases together over time promoting mental continuity through the years and g (intelligence), genes of better thinking that accompany longevity

Halogenated neurexin disruptors like latrotoxin could be picogram or even femtogram poisons or mind erasers or beneficial psychiatric drugs

Mt transporters and genes



Lithium during 2020 is used at batteries like electric vehicle batteries, seawater contains some lithium and it is possible genetically engineered ocean plants and new genetically engineered ocean plants could concentrate lithium and other materials at
their bulk, duckweed doubles its number every 24 hours and halophile duckweed could live in brackish or even saltwater and be automatically harvested

I read that some species of ants have queens that live 30 years, finding if these have any shared active-only-at-queen ants, queen bees and termite queens genetics could find homologous genes that increase human longevity when upregulated, they could
also blenderize and fractionate queen ants and find out if any of the fractions make c elegans, ants, and drosophila live longer prior to seeing if the chemicals at those fractions make mice and humans live longer as a longevity technology

It is nice to walk comfortably in the sunshine

Finding a version of melatonin that is both a longevity drug and a sleep drug with a shorter plasma half life from screening a library of molecular variants and finding out if epithalon or other pineal peptides has beneficial sleep inducing
characteristics is beneficial

If I had children I would find out if uncooked liquid free range whole eggs in milk on breakfast cereal with instant avocado halves was a nutritionally beneficial breakfast 3-4 days a week

A very simple souped up friendly roombaesque robot could activate autolock/unlock doors, lead young children to and from the school bus stop, and know what to do if things went awry like missed buses (preauthorized to call a cab, also bring children back
to where they live, message school, bring children out to cab, verify cab) it is possible with such a robot children could quantifiably safely leave for school after their parents leave the house, freeing up time, and increasing parental flexibility,
there is also the possibility that children could use the system to voluntarily leave for school later and attend school later to synchronize with parents schedules better

Psychologists could come up with some measure of, and measurable success at, and the psychological effects of, the percentage of children that would actually get themselves to school .3 to 2.5 hours after the parents started their commute, some children
of various ages could do it but not all, also there is weather to consider

The simple robot bus guides could also know what kids were allowed when to go over to their friends' houses so the children could change plans without confusing the robot or the parents

Based on acarbose which blocks absorption of enzymatically produced sugars at the GI tract a longevity probiotics that does something similar could be produced, perhaps a variant of longevity producing LKM512, acarbose causes flatulence in 4/5ths of the
people that take it, perhaps a probiotics that digests the things acarbose blocks but do not produce methane would be a longevity technology, also replacing the bacteria that excrete anything acarbose blocks with bacteria that do not make any of the
things acarbose blocks could be a longevity technology and even a slimming technology, acarbose looks like four sugar molecules connected together in a line, halogenating this might make an even more effective enzyme/receptor blocker, and, if it is
primarily a receptor blocker then it could have even greater longevity effects , also as a linear molecule acarbose has many T shaped and + shaped variations, screening a variety of acarbose isomers could find a better longevity drug, varying the -OH and
-H on the different sugars acarbose is made from produces trillions+ variants, if acarbose makes yeast,c elegans, daphnia, or 96 well plate fish live longer then the sugar variants could be screened on them first

Acarbose looks like it is made of six carbon sugars, a version of acarbose made from five carbon ring sugars like fructose could also have longevizing effects as fructose is half of dextrose and during 2019 there was a lot of added dextrose in foods, it
could be coadministered with acarbose for even greater longevity increases

Noting four sugars connected in a line looks a lot like a miniature starch polymer they could make a food additive that was actually a low molecular weight ministarch to make a longevizing food thickening agent, and if absent flatulence could be in
general use

Some longevity drugs work especially well when given to mice analogous to humans under about 5 or 10 years of age, they could find out if epithalon has a similar age advantage, i think melatonin has a published age advantage, and this could be researched
at analogously child mice, if it works on mice children would benefit from both greater longevity and better sleep

Immunizations can turn receptors permanently on, immunizing people so that pineal gland cytes made the most epithalon and melatonin as well as likely other chemicals is a possible longevity technology, another immunization would be to immunize all the
tissues so that all of the epithalon and melatonin, and possibly thymus chemicals like thymosin were either much more receptive to endogenous pineal and thymus chemicals or just switched to always on

SkQ is published as increasing longevity because it concentrates at the mitochondria, perhaps the phosphorus moiety that does this could be attached to gene therapy drugs for mitochondrial gene therapy, or transporting some scarce amino acid or some
other chemical like apoptosis inducer or reducer

Buckminsterfullerene C60 is published as causing mice to live 90% longer, along with repeating the study they could find out if other fullerene shapes (like bucky gelatin capsule shapes, longer tubes, or Ts) caused greater longevity as well

Methionine restricted diets cause mice to live longer, immunizing against methionine, causing less systemic availability, but some, could be a longevity technology

[MaxwellBuchanan] Paul Dear PhD, encourage him to research tests of the MWI

Online it says that mice with artificially lowered body temperatures live 12-20% longer,"You can also induce hypothermia by stimulating the heat-detecting cells in the hypothalamus, either by injecting capsaicin" suggesting that brain localized versions
of the capsiacin molecule or molecular variations could be longevity drugs

Removing the spleen makes rodents live longer, they could find out if immunizing against spleen chemicals makes mice live longer, one overly simple way to do this would be to electrophoresize homogenized spleens into 100 fractions add the
immunoactivating keyhole limpet proteins to their molecules and find out if any of the antibodies produced were longevity drugs, then re-electrophoresize that band to get higher resolution, they could also make a cytomembrane digest and find receptors
that were only on spleen tissue to develop drugs with, the genetics of spleen size could be longevity genes, they could breed mice with the tiniest spleens that are immunonormal and see if they live longer as well as screen super centenarian humans as to
spleen size and genetics

I read that some turtles increase their reproductive ability as they age, they could transfer those genes into shorter lived turtles that, if there are any, that do not do that and then see if the modified turtles live longer, if they do then they could
find homologous genes at mice and find out if they live longer as a way to find new human longevity genes and drugs, also voles fertility rises then remains constant throughout their lives and their genes are likely to be much more portable to mice

I read that clams sift through 30,000 times their own weight in water every 24 hours, people that would like to concentrate minerals or elements from seawater could breed or genetically engineer clams to concentrate elements of interest, porphyrins like
leghemoglobin exist in nature and glom metals

Infant carriers with vibration absorbers on the base, I saw a mom put her baby carrier on the floor of the bus, the baby did not wake up but the vibrations might have been more intense than she would have liked, gel pads at the base of baby carriers and
the brackets of car seats could heighten baby comfort

Yeast do a thing where when they don't get enough food 95% of them die so 5% can absorb the nutrients and make spores, I think I may have read that at mammals overcrowding increases mortality but I do not know if it changes lifespan, they could do
experiments on fish and mice to find out if overcrowding without overcrowding shares chemical signals that change lifespan, so a fish tank would be divided into sections with just a few fish on one side and a bunch of fish on the other with an opaque
barrier between them that permits water flow, then they could use ion exchange resins to take out each chemical in turn to find specific chemicals like proteins that have a lifespan effect, then they could immunize the fish against those chemicals to see
if they lived longer, they could do something similar with mice, perhaps with an odor passing barrier and a rotating feeder and floor that exposed the few mice to the saliva on food, dandruff, and pee of the crowded mice, then they could immunize the
mice and find out if they lived longer

I perceive children like higher pitched voices better, hearing aids for children could be pitch shifted and autotuned to whichever pitch they most prefer if adult hearing aids do not already have graphic equalizers they could pitch shift those as well

Viewing nursery rhyme videos they could still have the same or better fun songs but they could swap out the words with words that rhyme like "sheds, boulders,bees and flows" then have a picture of each appear on part of the video where the cartoon
children were touching their heads, shoulders, knees and toes, software could grab images off a search engine dynamically, ten hours of hskt would display 18,000 moments of ryhming images and sing the alternate lyrics, the text of the words could appear
onscreen as well, they could measure what amount of swap outs to original lyrics simultaneously made the children and learn the most new things, this could also be adjusted when the child or parent changed it, video streaming services could also make it

[MB] find the study that says fasting before chemotherapy is beneficial "almost entirely relieves the nausea fatigue and headaches associated with chemo (chemotherapy) while making the therapy many times more effective against the cancer "Cracking the
aging Code" Josh Mitteldorf

Longevity technology

An immunization against 60% of circulating insulin that only lasts until age 50, insulin correlated with aging, a kind of insulin for diabetics that does not cross the blood brain barrier, a probiotics that makes an almost insulin that occupies and
blocks insulin receptors

A way to test longevity drugs, some longevity drugs might have a discernable zone like 1mm of tissue youthfulness effect if implanted as microbeads that then diffuse throughout the life of a mouse or human, this is a dermis 1-3 mm localized effect on
tissue youthfulness rather than a systemic effect, at each cm^2 inject an array of 25 microbeads spaced 2mm apart, then at intervals inspect the skin to see if it is more youthful, 100 mice at 50 microbeads each is 400ish different longevity chemicals
tested, at each square meter at the sides of a cow or pig eight identical microbeads of 6.25 million different longevity chemicals can be tested for a p value on the decrease in local dermis aging for each of the 6.25 million different chemicals,
similarly rather than microbeads a tattoo maker with a microfluidic array reservoir of a plurality of different longevity chemicals in time release goop could make a continuously varying chemical line, kind of like rainbow yarn which might be simpler
than millions of spaced microbeads

Things that fill children with happiness

Video chat window on children's videos, they can talk with each other about the shared video and sing along together to nursery rhymes

MWI test on a computer chip, there is a 1.1 trillion transistor chip smaller than a keyboard, using similar technology and feature size a layer of radiation detectors, even photon detectors is placed beneath a layer of monoatomic or diffused to one per
1000 atoms that are radioactive, then another layer of radiation detectors are placed above that, the middle layer would also have sparse tesselated detectors, then baseline numbers would be recorded, then the chip is placed near various things to find
out if they effect the rate or angle of radioactive decay, this chip is then scanned at a plurality of physical locations, including rooms with different color schemes, on or at the apparatus path of physics experiments that could repetitively generate
MWI universes, and near people that say they hear paranormal voices, births, and weddings, this is to detect MWI local area effects and what I call IT pattern effects, the Detector searches for repeatable statistical anomalies, if none are found,
anywhere, then the detector might be a kind of insulator, if placed next to the head of a person that hears paranormal voices to find out if it decreases the voices or changes the ones they hear

Longevity technology

Melatonin attached to a moiety that keeps it from passing the blood brain barrier could be tested at 1x, 5x, 20x,50x,70x,100x,500x,1000x the dose published as causing a 20% longevity increase in rodents, circadian as well as extended release dosing could
be tried, there are a variety of BBB blocking moieties and the amino acid sequence GGG is one

A non BBB (blood brain barrier) passing version of deprenyl,thymosin, as well as epithalon could also be tried at heightening logarithmic doses to find out if bodyside only effects of these drugs are longevizing, and doses even higher than those
previously used at brain-reaching versions could have even greater longevizing ability

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