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Things on alibaba are noticeably cheaper than Fred Meyer, Amazon, or EBay, part of this I think is removing all the break-bulk and middlemen from the distribution, and products sometimes come direct from the factory, but if things continued to be
displayed for planned and impulse pickup at showrooms called"stores" during 2020 then a way to remove middlemen and stock showrooms is of value, a new form of shrink wrap product that is drone friendly could make this functional: 1) print all six sides
of a box or other object with invisible barcodes, these barcodes are only visible to ir cameras like those on the stocking drones, likely a QR (2D) code this would contain UPC code and more information 2) the plastic the pallet was wrapped in a: polymer,
form, and wrap style that a drone's laser could cut through (perhaps transparent ir absorbing plastic, a compact disk players laser diode can pop a balloon so a cutting grid projecting laser is likely near 10 cents on alibaba and the camera and computer
can verify there are no people around and like a backup vehicle it can beep for 5 seconds to keep people away from it before lighting the all pallet side cutting grid 3) with the pallet wrap out of the way the flying drones grab the stuff and take it to
the shelves or other CAD encoded 3D location (put the new empty flowerpot on the glass table next to the outdoor lounge furniture) 4) enumerate the stuff on the pallet and update showroom and manufacturer's database; during 2020 there was already
research on automated stocking
Longevity technology
a wellness technology that might be a longevity technology made of network theory math: from looking at effect "cascades" some of which are signalling cascades, the graphical diagram maps people make that have things that look like
interconnected circles make me think of networks, and that makes me think of math and computer analogies like swap space reducing hang time, solving or precluding race conditions; they could find these on purpose looking at
mRNA outliers, math,
computer science, and control theory; like, find the 95th percentile most cushioned networks and the 95th percentile least cushioned networks at 18 year olds and compare them to the same networks at 80 year olds, did the least cushy networks get cushier
or did they do something like break or start leaving some of their line and circle diagram neighbors out? If the least cushy networks are more frequently broken at 80 year olds, and potentially important stuff is not happening, and the really cushiony
networks may have shifted but are mostly fine that suggests finding the 1-5% least cushioned/cushy networks and doing gene therapy to make them more cushioned/cushy could cause less deleterious stuff over time
A really simplified and unclueful way of looking at this is find the weakest links and make them stronger, a much better way is to replace each circle at a diagram with an array, then make sure all the circles have the array capacity to support, be
supported, send and receive; find the circle arrays at greatest numerical (math) risk of going nonlinear or failing then adjust the circle neighbors so they omit prompting those failure conditions, where possible heighten the capacity of the at risk
circle array with drugs(chemicals), epigenetics or gene therapy (gene duplicates, different alleles, better promoters); the whole organism goal is to modify the 1-5% most likely to break to be at the body median (or less) of likely to break, crispr can
change 20,000 genes simultaneously in a mouse so crispr-ing the most at risk circles (1-5%) in the diagrams to create simultaneous improvement on many fronts, then after cushioning up the least OK nodes together find out if the organism (mouse, then
human) is healthier and perhaps longer lived than (thinking cushions) the crispr UNreupholstered version; if that works I think it is possible to make a smaller high lifespan/healthspan group of version optimized network nodes to base human drugs and
gene therapies on; interestingly these therapies do not (generally) treat a specific disease they just prevent a lot of disease; i think this network analysis and direct intervention can be applied before knowing what the network parts do,from things
like mRNA outliers
There may or may not be a correlation between nonpregnant cervix diameter and maximum cervical diameter while giving birth and an easier more dilated higher diameter birth cervix might go with a faster more pleasant birth experience for mother and baby,
if so then the genetics of both predictive nonpregnant cervix and actual fully dilated in-birth cervix could be linkable to genetics and if the genetics of optimal (likely 99.9th percentile) cervical size in-birth are non deleterious then making them
part of the germline of all homo sapiens that is people that is humans is beneficial
The same thing for shortest duration of labor, but with all the systems and hormones involved they would have to be even more careful to be assured a germline genetic
change is nondeleterious
Aspirin is described as repelling mosquito's online; new aspirins, propylene aspirin, sulfoaspirin, doubtful enteric CPP aspirin (dermis concentrating)(might reduce skin cancer and itch), halogenated salicylate,
Insecticide on bednets a color, when color fades time to re-treat bednets
63 cent alibaba adult bednet, divide into 4 pieces for four child bednets at 16 cents each
attractants can be used to cause mosquitos to fly into traps, I do not know the formulas anti-citronella, doubtful but halogenated ethynylized existing moquito attractants could make them 1000 times more potent which has similarities to 1000 times
cheaper, blood flavoring, gel electrophoresis of sweat, blood, then 1 mm gel slices a cm apart to find what they like, 10% landing rate but delicious on the feet nonvolatile attractant that lasts longer
Mosquito attractant and insecticide in one,
applied with alibaba 1 cent wet wipe to a .25 meter^2 area of a bednet attracts them and wipes them out with human co2 and moisture as baseline co-attractants to get the mosquito's to visit the insecticide wet-wiped area; perhaps double or quadruple
strength insecticide at the wet wipe amplifies termination compared with multiple landings on an entire bednet, human emdogenenous somatic CYP enzyme susceptible insecticide (ases like deaminase, hydroxylase, many others) rapidly decomposes insecticide
if a human absorbs it
Antimalarial tail peptide, my perception is that the mosquito parasite (malaria) falciparum something is a eukaryote thus has lots of receptors, tail peptides can turn receptors from hypersensitive to off, a blend of say 11-40 tail peptides could
terminate falciparum or keep it from reproducing and be administered at the dwelling from a 40 dose nasal spray container, Cell penetrating peptides that work on falciparum could make the effective dose many times more potent, maybe, causing it to be
many times cheaper
Nasal spray improvement technology, something that might be called wonderberry makes a variety of foods taste sweeter, it is possible that people that vomit through their nose actually also taste it there, snorting wonderberry chemicals might actually
make snot have a detectable pleasant flavor rewarding people that are compliant with their nasal spray drugs (like peptides, GDF-11, klotho protein etc) also fast acting opiate peptides at really minte quantities (picograms have an effect on rodents)
could obviate swimmers nose effect from nasal spray, nasal tailored liposomal formula could make the opiate peptides absorb better and possibly faster as could cell penetrating peptides, when the nasal spray drains to the back of the throat it goes to
the stomach breaking up the peptides, non mu receptor (get high opiate receptor) opiate peptides may exist that also have local anesthetic effects, combining these two (wonderbery and opiate peptide) could make a nearer sensation less nasal spray with a
sweetness reward
Push up magnetic domains, HDD, hyper dielectric (plasmonic) dielectrics could be used at RAM capacitors and transistors, maybe, peltier effect RAM cooling, faster clock speed with longer life, peltier on top layer of wafer, peltier top GPU chips (likely
already considered seems like peltier CPUs must have been thought of) diamond CVD vertical vias and diamond top of wafer could assist this, heat conductive ceramic or polymer at IC bodies could be 60% tungsten metal particles as they do not melt when the
polymer/ceramic is formed, goes well with peltier RAM/GPU/CPU,
CPP paleness bremelanotide could have higher dose potency and 33-480 times (published) more rapid action on the brain, if (when) they find receptors associated with the male and female sexual refractory period then tail peptides and proteins and RNA can
be made to park those receptors into continuous ready-to-go pre-orgasm mode removing the sexual refractory period, as a drug this could be an all day delivery at one month of transdermal patch function, if this is without deleterious effects the receptor
tail modifying peptides/proteins/RNAs are beneficial to make a part of the homo sapiens, that is humans that is people's germline genome
Live in-computer over clocking of RAM, RAM has a speed, it is possible at on motherboard RAM or stick (card) RAM adjusting the RAM speed (at a mechanism automatic to the computer but with OS addressability) upward and doing a diagnostic (like 4 billion
cycles of write/read verify) could find the optimal higher speed for the RAM, at any of motherboard level, memory card level or even individual IC level possibly making it 25-100% (noting peltier RAM) faster, high utility at server farms (internet), CAD,
games,video editing, memory intensive applications could go 25-100% faster; another possibility is faster optical fiber internet, i imagine there is a thing kind of like an optical demultiplexer chip (serial to parallel), over clocking it could permit a (
2020) 100 GbS chip to receive data at 125-200 GbS if the part is on-computer overclocked and verified
Better quantum dots, quantum dots above the second standard deviation might be unusually spectrally pure in output and stimulate ability, it is possible spraying (perhaps electrostatically) quantum dots in a magnetic field takes advantage of their
diamagnetism to sort them on mass and "alloy" ratio predictability producing a source of better than average quantum dots, noting quantum dots are much bigger than atomic isotopes perhaps alternatives to magnetic separation could be based on isotope
separation; gas centrifuge like non halogenated quantum dots might simply be centrifugally seperable with a membrane, also i read about aqueous membrane separation of isotopes, perhaps quantum dots at a nonpolar or weakly polar (DMSO in liquid hexane)
solution, perhaps with charge from being energized with UV, could diffuse through a membrane, repeatedly (kind of like reflux) to concentrate the ones of near identical mass and near identical e- charge from UV, high volume uses for spectrally purer
quantum dots include phone, computer, and video displays, other volumes would support medicine and research
4-8 bit matrix logic, better and, nand, or not clusters, better predictive branching 1 or 4 GHz 4 or 8 level (possibly actual vertical layer stacks on wafer) could big words 16 bits of 4/8 matrices benefit servers and databases and CAD and games and
velocitize queries; MBU, math batching unit, also FPGA (FPGmatrixA) version
CeO nanoparticles, are quantum dot sized ones better
The rubber finger grips of pens feel different when they are velvet textured than smooth, perhaps velvet textured condoms could be measured to see if they are more pleasurable to women
new endogenously produced PDE5 inhibiting (viagra-like) peptides turn off during pregnancy, cause erections, clitoral engorgement,
beautiful face that causes others to be nice to you at repose; internet survey, may have previous writing, an improvement
Non genital erogenous zones, technology that causes them to be larger and more sensitive without increasing skin snesitivy to nonoptimal levels. the brain “body part fiagram”, dubious but hox genes, very dubious about the hox genes, 99th percentile
of nongenital erogenous zone sensitivity
I have written about technology to beneficially cause all males to have erect penises 8 inches or longer with 6 inch girth from engineering the homo sapiens, that is human, that is people globally’s germline. Noting that, today during October 2020AD I
perceive some males would like to make their erect penises longer or thicker it is possible a modified condom with a gel form tip form that is more pleasurable to percuss and rub at than an actual vagina that penis is in contact with is possible; the
technology is: Think of an extra long condom with a 2 inch long blob of vinyl gel at the end, this causes deeper efective penetration for interested men and women and optional increase in girth at the blob area that would be felt as the head of the penis;
(I) shaped center firmness beam, because the condom provides Also, if it goes lopsided during sex that, to my perception is unproblematic; The transition from condom lumen (hollow space) through gel stages could start out very liquidy and pushable
into by the penis when putting the length extending concom on, the gel grading from push-aside mousse gel gradually to soft gel, with firm gel then very firm PVC at the 2 inches of tip, to make the gel form condom more pleasurable than bare contact with
an actual vagina the gel form tip and mousselike first gel layer heat up (it is my perception that a particularly warm or hot vagina is even more pleasurable to have sex with, so having the gelform length extension condom heat up to the most pleasurable
temperature could possibly make it feel better than a bare penis at a normal temperature vagina;
chinese finger trap on thrusting, glans rim can nest with annular groove at extension gel shape, condom style , 1-2 cents each at alibaba (condom is 1 cent/each), actual 1 hour chemistry of generating warmth to make the extension gel shape even more
pleasureable than a regular vagina at the extension gel shape, one source of the chemistry for that:During about 1992AD I experienced sex with a woman who used a contraceptive vaginal insert that foamed and generated a lot of warmth, even heat

During about 1992AD I experienced a contraceptive vaginal insert that foamed generated a lot of warmth, even heat it is possible that the birth control effectiveness of vaginal inserts goes up with antibodies to sperm surface proteins attached to sperm
terminators like vagina-mild detergent (nonoxynol-9 is a 2020AD condom sperm terminator or even Zinc ion, CPP highly localized to sperm might be a functional thing, if it does CPP-(link)-apoptosis peptide or protein might work if harmless to the vagina,
sperm tail adherered proteins or peptides, or polymers, or even, just possibly sperm tail length sticky strings, could also be vaginal insert contraceptives, or also condom interior/exterior ingredients



Making genetically enhanced sperm better, wikipedia identifies a middle piece where the tail is surrounded by mitochondria, double or half that could variously make them able to swim faster or use less food to stay fertile longer during storage like
encapsulation or better (nuvaring)
tail dip jig is only osmotic area to puff up with food

Other sperm foods at the medium or storage medium could be acetyl-CoA, “CoA is acetylated to acetyl-CoA by the breakdown of carbohydrates through glycolysis and by the breakdown of fatty acids through β-oxidation. Acetyl-CoA then enters the citric
acid cycle, where the acetyl group is oxidized to carbon dioxide and water, and the energy released is captured in the form of 11 ATP and one GTP per acetyl group.”
There is just a possibility that becuase the sperm mitochondria have TCA cycle and can process lipids, that a lipid enriched sperm has lots of food energy ( 8 cal per gram compared with 4), “At low glucose levels, the production of acetyl-CoA is linked
to β-oxidation of fatty acids”

Taking human tissue homogenate, put it in supportive medium and see which human tissues have the longest living mitochondria, those mitochondrial types could be instantiated at sperm to generate longer sperm life and greater motility; also compare
cytosol and organelle function at longest lived tissues and noting some human tissues revive after lyophilization https://www.freepatentsonline.com/y2018/0104282.html the human tissue cytes that revive after lyophilization are a guide to the organelles,
their particular size, chemistry that permit successful revival from hydration from lyophiliization

The patent describes successful tissue (skin) lyophilization media with >70% revival that they could test this media on sperm, this may work now:Lyoprotectant

Solution
Composition Cell Viability Comments

10% DMSO, 12.5% <50% viable cells Not selected
HSA in D-PBS
25% HSA in D-PBS No viable cells Not selected
0.25M Trehalose, Majority of cells are Not selected
12.5% HSA in D- viable
PBS
0.1M Trehalose in No viable cells Not selected
D-PBS
0.25M Trehalose in Majority of cells are Inconsistent results
D-PBS viable
0.5M Trehalose in Majority of cells are Selected: highest cell
D-PBS viable viability by qualitative
assessment with simplest
composition

1M Trehalose in D- Majority of cells are Similar results to 0.5M
PBS viable trehalose.
0.25M Trehalose, Majority of cells are Not selected, causes brown
1 mg/mL Catechin in viable coloration of amnion
D-PBS

“samples from this experiment were tested for cell viability, and VLAM should have >70% viable cells for the rinse to deem acceptable.”

A technology that could raise the viability of lyophilized genetically enhanced sperm is coculturing, or just mixing, then 24 hours of stabilization, dermatocytes with sperm cytes such that the proportions keep the sperm from ever overlapping, the cell-
to-cell contact surface may be particularly benign, and along with regular dermatocytes if seminal vesicle membrane tissues lyophilize and revive well then that could be tissue cultured to be used as the mix-with-sperm possible lyophilization preservative

Lyophilizing freeze dries sperm, but what of partial lyohilization, frozen thawed sperm is fertile, so at a range of 100 samples, each at 1%, 2%, 3%…100% dewatered from partial freeze drying spread out as a monolayer powder on a porous bottom (polymer)
sheet, which of the 1-100 percentage steps survive, after freezing revive? And, what is the foil package under nitrogen survival or microencapsulation survival of each stepwise 1%? At microencapsulation 100% of fresh sperm survive 1 month (published)
There is an aqueous osmotically neutral way to have a 50% water, 50% some other thing that has very gradual osmotic change (maybe its just stirring and titration) such that the cyte omits shriveling or bursting, The some other thing might be fructose or
a sperm edible electrically neutral amino acid; What is the fresh sperm, lowest percentage of cyte body water that can support a moving vital the moving vital sperm number, Then find out which least water % prep environment permits the revival of those
no-longer-swimming -sperm? Those numbers suggest a possible number for a fractional lyophilization, high revival after storage at consumer packaging genetically enhanced sperm product ; If fresh sperm still swim at 70% less body water, that means
something, if sperm that have ceased swimming on their own at 80% body water can be revived to swim starting at 50-100% body water that is something

It is pretty likely 99% hydrated is fine, so what about if 50% hydrated stays functional for many months, is a humid gel microbead powder, that can go in a cervical ring (nuvaring) or break n shake vaginal applicator

Freeze drying the already dehydrated, but still vital sperm could also work better as the interval of freezing is less: (If fresh sperm still swim at 70% less internal body water, that means something, if sperm that have ceased swimming on their own at
80% internal body water can be revived to swim starting at 50-100% internal body water that is something) according to something like that you could lyophilize the 70% osmotically dehydrated sperm with just 30% of the shock-to-sperm interval

Thaw omostic internal organelle “shock”; when it rehydrates with water, but the 1st 10% of rehydration comes with a very high organelle ion difference so it does anything from physically popping them or shriveling them, to wiping out their chemistry.
pH could change an order of magnitude (1 pH number) just from having the first minute of rehydration dissolve the cytoplasm’s ions; As a lyophilization survival strategy preload sperm with ion balancers like more K(potassium) without inorganic ion so
like Kaminoacid, or even K-ATP, if it the other way then more chloride, (Aminoacid-cl?) (MgCl2?) calcium chloride?; Perhaps if cyte is naturally acidic, bicoarbonate ion like Kco3 or even amino acidCO3 or MgOH would balance and buffer pH throughout
entire 1-100% of hydration change

Also, a 1-100% (100) rehydration steps-maintained buffer and ratio maintener is new to me, as a“stepwise no-shock buffer;

Other buffer chemicals for osmotic shock, or also misaligned anion and cation ratios from stepwise hydration: if cyte is naturally basic, buffer the 1-100% cytoplasm hydration steps (10-100x ion concentration during the first 2 seconds after pouring or
shaking with water/plasma replacer) Treat basicity with citric acid (TCA cycle), Malic Acid (TCA cycle), Acetic acid (also a food for some cytes); Perhaps if cyte is naturally acidic, bicoarbonate ion like Kco3 or even amino acidCO3 or MgOH would balance
and buffer pH throughout entire 1-100% of hydration change
If sperm as part of their functionality produced their own buffer (acid+salt, others) chemicals, then they might revive better after lyophilization

So, at a break n shake lightstick-like lyophilized sperm reconsituter/rehydrator the velocity at which the water reaches the interior of the sperm cytes might determine the amount of mess-up to the cyte so rehydrating fully as rapidly as possible might
cause greater reconstituted genetically enhanced sperm vitality, one way to do that could be nonharmful sonic vibration. The Break n Shake genetically enhanced sperm stick vaginal insert could have a button battery and a specially tuned piezoelectric
buzzer for 2 cents (alibaba; piezo buzzer with wires 1 cent, battery .6 cent), the tuned sonication would make the regularization of cyte pH, ion concentrations, and other things return to those of fesh sperm much more rapidly than just the break n shake
n wait 3 minutes approach. Being able to use the sperm in less than three minutes is beneficial for convenience, and adding a color change LED (from blue to green) (green means go) to the break n shake stick that already has a battery and piezo element
is likely less than 1 cent

buzzer(pH and ion gradients 100 times larger than usual concentrations, totally different chemical ratios during redissolving of cytoplasm and plumping up organelles phase)
piezoelectric get water in the organelles rapidly from vibration button cell (alibaba .6 cents)

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