On Sunday, June 19, 2022 at 9:42:45 PM UTC-4, Mitch Raemsch wrote:
that would not be an evolutionary advantage.
The following technical paper attempts to show that the DISadvantage was very minor:
https://academic.oup.com/emph/article/2019/1/221/5556105
Past experience with you suggests that you aren't interested in answers to your own questions,
but the following may interest some readers in the rest of the paper.
Opening paragraph:
"Most animals are able to synthesize ascorbic acid (AA) from glucose in either the kidney or the liver [1].About 61 million years ago, some mammals and primates, including our human ancestors, lost the ability for this endogenous vitamin C synthesis [2].
This occurred due to the inactivation of L-gulono-lactone oxidase (GLO) gene with the consequence that the last step of the ascorbate synthesis from glucose was blocked. From then on, these species, including some primates, guinea pigs and Indian fruit
bats, have been dependent on dietary, daily intake of AA."
The paper argues that this loss was offset by our remote ancestors developing a remarkable
substitute for GLO:
"RBCs Glut-1 expression and resulting vitamin C recycling decreased the required daily amount by up to 100-fold."
The rest of what you wrote is hardly worth commenting on:
It exists for an immune advantage.
You've switched the referent of "It" from the loss of the vitamin to the vitamin itself, and you are indulging in speculation.
Look up the word "scurvy," and be enlightened about the main reasons
we *need* vitamin C.
Linus Pauling was right.
Are you bedazzled by the title of an undated article?
"Vitamin C, Linus Pauling was right all along. A doctor's opinion"
The article itself talks about miracle cures, yet fails to give a documented example of a single one. To make things even more suspicious, it
does give citations for opposing claims by the NIH.
Mitchell Raemsch
Judging from others' reactions to you, they aren't interested in making
silk purses out of sow's ears, and I might stop trying to do that
myself if you don't start trying to pass the Turing test.
Peter Nyikos
Professor, Department of Mathematics
University of South Carolina -- standard disclaimer --
https://people.math.sc.edu/nyikos/
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