• The TWO chromosome fusions

    From JTEM is so reasonable@21:1/5 to All on Thu Dec 22 18:57:55 2022
    https://www.thetech.org/ask-a-geneticist/48-46

    Alright, I tried to bring this up in the past, I know
    I mentioned it, but here we go again...

    So I don't know anybody who thinks that a baby
    was born 800k or 2 million years ago and,
    suddenly, humans stopped having 48 Chromosomes
    and started having 46.

    Nope.

    What likely happened is that /Some/ ancestors
    started having 47.

    AND THEN, either they bumped into another group
    that also commonly had 47, resulting in one group
    with 46, or it was always just one group and then
    some kind of Found Effect got them all playing
    "Monster Mash" and, before you know it, everyone
    was born with 46...

    I'm on record favoring the multiple events scenario.

    Why? Because it doubles the size of our starting
    population, giving them the best chance to take off,
    take over. And...

    Because the fusion wouldn't be any kind of advantage,
    as far as I can see. It likely would have been a
    disadvantage. It wouldn't have stopped breeding but
    it wouldn't have helped, either. Might've slowed things
    down. But, just for the sake of argument, let's look at
    the single event scenario.

    To me this plays to r/K selection. Anything that hampers
    reproduction, even just a little, increases the significance
    of every offspring. Also...

    If you had a gorilla style reproductive strategy, one male
    a a bunch of females, a mutation does get the opportunity
    to take root... take over.

    Right?

    If such a mutation crops up in a single female out of a
    group, there's an excellent chance it will be drowned out
    by the breeding of all the females who don't have it. And
    it's the same deal in any male within a population were
    males all have a go at the breeding thing.

    ESPECIALLY IF THE MUTATION PRESENTS A SMALL
    DISADVANTAGE IN BREEDING!

    So if we're talking a single event -- the chromosome
    fusion popped up in one group, and that group evolved
    into modern humans -- to me it suggests that this was
    not a sexually selected group, that a lot of investment
    went into each offspring and we did not have a "Quantity
    has a quality all of it's own" reproductive strategy.

    Or, this had to become the case VERY quickly, once the
    fusion happened...

    ::Discuss::




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    https://jtem.tumblr.com/post/704349243109949440

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