Thyroidal and Extrathyroidal Requirements for Iodine and Selenium:
a Combined Evolutionary and (Patho)Physiological Approach
DA Janneke Dijck-Brouwer cs 2022
Nutrients 14 (19) 3886 doi org/10.3390/nu14193886
Iodide is an anti-oxidant, oxidant & thyroid hormone constituent. Seleno-proteins are needed for tri-iodo-thyronine synthesis, its deactivation & iodine release.
They also protect thyroidal & extra-thyroidal tissues from H2O2 used in the ‘peroxidase partner system’.
This system produces thyroid hormone & reactive iodine in exocrine glands to kill microbes.
Exocrine glands recycle iodine, and with high urinary clearance require constant dietary supply, unlike the thyroid.
Disbalanced iodine-selenium explains relations between thyroid auto-immune disease TAD & cancer of thyroid & exocrine organs: stomach, breast, prostate.
- Sea-food is iodine-unconstrained, but selenium-constrained.
- Terrestrial food contains little iodine, while Se ranges from highly deficient, to highly toxic.
Iodine vs TAD is U-shaped, but only low Se relates to TAD.
Oxidative stress from low Se, and infection from disbalanced I-Se, may generate cancer of thyroid & exocrine glands.
Traditional Japanese diet resembles our ancient sea-shore-based diet, and relates to a-fore-mentioned diseases.
Adequate iodine might be in the milligram range, but is toxic at low Se. Optimal seleno-protein-P at 105 µg Se/day agrees with Japanese intakes.
Se upper limit may remain at 300–400 µg/day.
Sea-food combines I, Se & other critical nutrients.
It brings us back to the sea-shore diet that made us what we currently still are.
:-)
inland basins etc. The malnutrition of trace elements is mainly due to poor agro-economic practices, populations unable to get broadband foods in their carb-heavy diet, which did not occur amongst ancient nomadic hunting & gathering populations.Thyroidal and Extrathyroidal Requirements for Iodine and Selenium:
a Combined Evolutionary and (Patho)Physiological Approach
DA Janneke Dijck-Brouwer cs 2022 Nutrients 14 (19) 3886 doi org/10.3390/nu14193886
Iodide is an anti-oxidant, oxidant & thyroid hormone constituent. Seleno-proteins are needed for tri-iodo-thyronine synthesis, its deactivation & iodine release.
They also protect thyroidal & extra-thyroidal tissues from H2O2 used in the ‘peroxidase partner system’.
This system produces thyroid hormone & reactive iodine in exocrine glands to kill microbes.
Exocrine glands recycle iodine, and with high urinary clearance require constant dietary supply, unlike the thyroid.
Disbalanced iodine-selenium explains relations between thyroid auto-immune disease TAD & cancer of thyroid & exocrine organs: stomach, breast, prostate.
- Sea-food is iodine-unconstrained, but selenium-constrained.
- Terrestrial food contains little iodine, while Se ranges from highly deficient, to highly toxic.
Iodine vs TAD is U-shaped, but only low Se relates to TAD.
Oxidative stress from low Se, and infection from disbalanced I-Se, may generate cancer of thyroid & exocrine glands.
Traditional Japanese diet resembles our ancient sea-shore-based diet, and relates to a-fore-mentioned diseases.
Adequate iodine might be in the milligram range, but is toxic at low Se. Optimal seleno-protein-P at 105 µg Se/day agrees with Japanese intakes. Se upper limit may remain at 300–400 µg/day.
Sea-food combines I, Se & other critical nutrients.
It brings us back to the sea-shore diet that made us what we currently still are.
:-)
Marine seafood simply has a higher concentration of some chemicals found in freshwater ecosystems, salt, (selenium, iodine = trace elements) accumulate in any riparian lacustrine basin, including the Congo basin, the Atacama desert region, California
Op donderdag 22 september 2022 om 14:35:39 UTC+2 schreef DD'eDeN aka note/nickname/alas_my_loves:inland basins etc. The malnutrition of trace elements is mainly due to poor agro-economic practices, populations unable to get broadband foods in their carb-heavy diet, which did not occur amongst ancient nomadic hunting & gathering populations.
Thyroidal and Extrathyroidal Requirements for Iodine and Selenium:
a Combined Evolutionary and (Patho)Physiological Approach
DA Janneke Dijck-Brouwer cs 2022 Nutrients 14 (19) 3886 doi org/10.3390/nu14193886
Iodide is an anti-oxidant, oxidant & thyroid hormone constituent. Seleno-proteins are needed for tri-iodo-thyronine synthesis, its deactivation & iodine release.
They also protect thyroidal & extra-thyroidal tissues from H2O2 used in the ‘peroxidase partner system’.
This system produces thyroid hormone & reactive iodine in exocrine glands to kill microbes.
Exocrine glands recycle iodine, and with high urinary clearance require constant dietary supply, unlike the thyroid.
Disbalanced iodine-selenium explains relations between thyroid auto-immune disease TAD & cancer of thyroid & exocrine organs: stomach, breast, prostate.
- Sea-food is iodine-unconstrained, but selenium-constrained.
- Terrestrial food contains little iodine, while Se ranges from highly deficient, to highly toxic.
Iodine vs TAD is U-shaped, but only low Se relates to TAD.
Oxidative stress from low Se, and infection from disbalanced I-Se, may generate cancer of thyroid & exocrine glands.
Traditional Japanese diet resembles our ancient sea-shore-based diet, and relates to a-fore-mentioned diseases.
Adequate iodine might be in the milligram range, but is toxic at low Se. Optimal seleno-protein-P at 105 µg Se/day agrees with Japanese intakes. Se upper limit may remain at 300–400 µg/day.
Sea-food combines I, Se & other critical nutrients.
It brings us back to the sea-shore diet that made us what we currently still are.
:-)
Marine seafood simply has a higher concentration of some chemicals found in freshwater ecosystems, salt, (selenium, iodine = trace elements) accumulate in any riparian lacustrine basin, including the Congo basin, the Atacama desert region, California
My little boy, why this irrelevant blabla??Cite please:
Already caught yor kudu?Kudu fish trap trout. So?
:-DDDHappy mermaid.
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