Katalin Karikó and Drew Weissman, who together identified a chemical
tweak to messenger RNA, were awarded the Nobel Prize in Physiology or Medicine on Monday. Their work enabled potent Covid vaccines to be made
in less than a year, averting tens of millions of deaths and helping the world recover from the worst pandemic in a century.
Dr. Karikó, the 13th woman to win the prize, languished for many long
years without funding or a permanent academic position, keeping her
research afloat only by latching on to more senior scientists at the University of Pennsylvania who let her work with them. Unable to get a grant, she said she was told she was “not faculty quality” and was forced to retire from the university a decade ago. She remains only an adjunct professor there while she pursues plans to start a company with
her daughter, Susan Francia, who has an M.B.A. and was a two-time
Olympic gold medalist in rowing.
The mRNA work was especially frustrating, she said, because it was met
with indifference and a lack of funds. She said she was motivated by
more than not being called a quitter; as the work progressed, she saw
small signs that her project could lead to better vaccines. “You don’t persevere and repeat and repeat just to say, ‘I am not giving up,’” she
said.
At first, other scientists were largely uninterested in taking up that
new approach to vaccination. Their paper, published in 2005, was
rejected by the journals Nature and Science, Dr. Weissman said. The
study was eventually accepted by a niche publication called Immunity.
But two biotech companies soon took notice: Moderna, in the United
States, and BioNTech, in Germany, where Dr. Karikó eventually became a senior vice president. The companies studied the use of mRNA vaccines
for flu, cytomegalovirus and other illnesses. None moved out of clinical trials for years.
Then the coronavirus emerged.
https://www.nytimes.com/2023/10/02/health/nobel-prize-medicine.html
The vaccines have saved 14-20M lives. Countless covid hospitalisations. Blessed are experts.
The companies studied the use of mRNA vaccines for flu, cytomegalovirus and other illnesses. None moved out of clinicaltrials for years.
And somehow it was magically developed and approved for Covid in six months :)
The companies studied the use of mRNA vaccines for flu, cytomegalovirus and other illnesses. None moved out of clinicaltrials for years.
And somehow it was magically developed and approved for Covid in six months :)
The companies studied the use of mRNA vaccines for flu, cytomegalovirus and other illnesses. None moved out of clinicaltrials for years.
On Monday, October 2, 2023 at 12:57:41PM UTC-7, PeteWasLucky wrote:> > The companies studied the use of mRNA vaccines for flu, cytomegalovirus and other illnesses. None moved out of clinical > trials for years.> And somehow it was magically developedand approved for Covid in six months :) Not "magically." Wasn't development accelerated by the guy you plan to vote for next year?The prize is well-deserved for both scientists in this case and it's nice they both lived to see their work validated.
Gracchus <grac...@gmail.com> Wrote in message:rdeveloped and approved for Covid in six months :) Not "magically." Wasn't development accelerated by the guy you plan to vote for next year?The prize is well-deserved for both scientists in this case and it's nice they both lived to see their work
On Monday, October 2, 2023 at 12:57:41 PM UTC-7, PeteWasLucky wrote:> > The companies studied the use of mRNA vaccines for flu, cytomegalovirus and other illnesses. None moved out of clinical > trials for years.> And somehow it was magically
I don't want to vote for any of these two.
Biden is almost gone mentally and Trump we know the guy.
I definitely wish for another respectable candidate. I believe we need switch back and forth between the two parties.
On Monday, October 2, 2023 at 1:40:07PM UTC-7, PeteWasLucky wrote:> Gracchus <grac...@gmail.com> Wrote in message:r > > On Monday, October 2, 2023 at 12:57:41 PM UTC-7, PeteWasLucky wrote:> > The companies studied the use of mRNA vaccines for flu,cytomegalovirus and other illnesses. None moved out of clinical > trials for years.> And somehow it was magically developed and approved for Covid in six months :) Not "magically." Wasn't development accelerated by the guy you plan to vote for next year?
Switching back and forth is the only way to prevent things from
deteriorating badly and quickly since we know we aren't going to have additional parties.
Gracchus <gracchado@gmail.com> Wrote in message:rand approved for Covid in six months :) Not "magically." Wasn't development accelerated by the guy you plan to vote for next year?The prize is well-deserved for both scientists in this case and it's nice they both lived to see their work validated.
On Monday, October 2, 2023 at 12:57:41PM UTC-7, PeteWasLucky wrote:> > The companies studied the use of mRNA vaccines for flu, cytomegalovirus and other illnesses. None moved out of clinical > trials for years.> And somehow it was magically developed
I don't want to vote for any of these two.
Biden is almost gone mentally and Trump we know the guy.
I definitely wish for another respectable candidate. I believe we need switch back and forth between the two parties.
PeteWasLucky <waleed.khedr@gmail.com> writes:>> Switching back and forth is the only way to prevent things from> deteriorating badly and quickly since we know we aren't going to have> additional parties.Haven't we been doing that already for a while?Truman (D)Eisenhower (R)Kennedy (D)Johsnon (D)Nixon (R)Ford (R)Carter (D)Reagan (R)Bush (R)Clinton (D)Bush (R)Obama (D)Trump (R)Biden (D)So you'd like the status quo, more or less?
jdeluise <jdeluise@gmail.com> Wrote in message:r
PeteWasLucky <waleed.khedr@gmail.com> writes:>> Switching back andforth is the only way to prevent things from> deteriorating badly and
quickly since we know we aren't going to have> additional
parties.Haven't we been doing that already for a while?Truman
(D)Eisenhower (R)Kennedy (D)Johsnon (D)Nixon (R)Ford (R)Carter
(D)Reagan (R)Bush (R)Clinton (D)Bush (R)Obama (D)Trump (R)Biden (D)So
you'd like the status quo, more or less?
I wouldn't mind having a DD or RR pattern followed by a party flip as
long as the current D or R is doing a good job, but I can't tolerate
the current D for a second term.
PeteWasLucky <waleed.khedr@gmail.com> writes:> jdeluise <jdeluise@gmail.com> Wrote in message:r>> PeteWasLucky <waleed.khedr@gmail.com> writes:>> Switching back and> forth is the only way to prevent things from> deteriorating badly and> quickly sincewe know we aren't going to have> additional> parties.Haven't we been doing that already for a while?Truman> (D)Eisenhower (R)Kennedy (D)Johsnon (D)Nixon (R)Ford (R)Carter> (D)Reagan (R)Bush (R)Clinton (D)Bush (R)Obama (D)Trump (R)Biden (D)So> you'd like
On Monday, October 2, 2023 at 11:48:50 AM UTC-7, Pelle Svanslös wrote:
Katalin Karikó and Drew Weissman, who together identified a chemical tweak to messenger RNA, were awarded the Nobel Prize in Physiology or Medicine on Monday. Their work enabled potent Covid vaccines to be made
in less than a year, averting tens of millions of deaths and helping the world recover from the worst pandemic in a century.
Dr. Karikó, the 13th woman to win the prize, languished for many long years without funding or a permanent academic position, keeping her research afloat only by latching on to more senior scientists at the University of Pennsylvania who let her work with them. Unable to get a grant, she said she was told she was “not faculty quality” and was forced to retire from the university a decade ago. She remains only an adjunct professor there while she pursues plans to start a company with her daughter, Susan Francia, who has an M.B.A. and was a two-time
Olympic gold medalist in rowing.
The mRNA work was especially frustrating, she said, because it was met with indifference and a lack of funds. She said she was motivated by
more than not being called a quitter; as the work progressed, she saw small signs that her project could lead to better vaccines. “You don’t persevere and repeat and repeat just to say, ‘I am not giving up,’” she
said.
At first, other scientists were largely uninterested in taking up that
new approach to vaccination. Their paper, published in 2005, was
rejected by the journals Nature and Science, Dr. Weissman said. The
study was eventually accepted by a niche publication called Immunity.
But two biotech companies soon took notice: Moderna, in the United
States, and BioNTech, in Germany, where Dr. Karikó eventually became a senior vice president. The companies studied the use of mRNA vaccines
for flu, cytomegalovirus and other illnesses. None moved out of clinical trials for years.
Then the coronavirus emerged.Cool.
On Monday, October 2, 2023 at 12:57:41 PM UTC-7, PeteWasLucky wrote:
The companies studied the use of mRNA vaccines for flu, cytomegalovirus and other illnesses. None moved out of clinicaltrials for years.
And somehow it was magically developed and approved for Covid in six months :)Not "magically." Wasn't development accelerated by the guy you plan to vote for next year?
The prize is well-deserved for both scientists in this case and it's nice they both lived to see their work validated.
Meanwhile, I received the latest version of this marvelous vaccine just last week. Thank you Karikó and Weissman!
jdeluise <jdel...@gmail.com> Wrote in message:rknow we aren't going to have> additional> parties.Haven't we been doing that already for a while?Truman> (D)Eisenhower (R)Kennedy (D)Johsnon (D)Nixon (R)Ford (R)Carter> (D)Reagan (R)Bush (R)Clinton (D)Bush (R)Obama (D)Trump (R)Biden (D)So> you'd like the
PeteWasLucky <waleed...@gmail.com> writes:> jdeluise <jdel...@gmail.com> Wrote in message:r>> PeteWasLucky <waleed...@gmail.com> writes:>> Switching back and> forth is the only way to prevent things from> deteriorating badly and> quickly since we
Thanks for the message. We got it.
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