• Wonder pill that makes you skinny WITHOUT dieting moves one step closer

    From _@21:1/5 to All on Thu Mar 23 13:07:25 2023
    1) The pill isn't a pill, it's injections, & it's
    thus far only been tested in mice.

    2) They are developing a pill version of
    the drug and hope to start human trials
    this year.

    3) The drug is not being developed to
    deal with Cellosis (new clarifying name
    for type 2 diabetes) but a side effect of
    the drug is reduction in risk of getting
    Cellosis.

    4) References to weight loss in the art-
    icle, unclear if the drug induces weight
    loss or simply prevents weight gain, so
    the "makes you skinny" part of the title
    may be exaggerating the actual impact
    of the drug.

    ---
    March 22 2023 https://www.dailymail.co.uk/health/article-11889987/Wonder-pill-makes-skinny-WITHOUT-dieting-exercising.html
    ---

    ... The drug — named CPACC — is a small
    molecule that works by inhibiting the uptake
    of magnesium by mitochondria in cells. The
    team is now looking to patent the drug, but
    warn it may still be years before it reaches
    pharmacies. ...

    ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~

    Pro-Humanist FREELOVER, Insulinitis (Islit)
    since age 5, got it in March 1961 https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    C.ure I.nsulinitis A.ssociation
    ASAP! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    The Sooner The Better! https://prohuman.net/glucoseanomaliesresearch.htm

    - - -

    The old confusing way which all-too-often
    involves folks using the diabetes / diabetic
    words without a clarifier:

    diabetes / diabetic without a clari
  • From _@21:1/5 to All on Tue Apr 11 08:11:24 2023
    Follow-up:

    Is this drug too good to be true?

    Time will tell.

    - - -
    April 10 2023

    New Weight Loss Drug Works Despite
    a High-Sugar Diet
    https://healthnews.com/news/weight-loss-on-a-high-sugar-diet/
    - - -

    Photo implying that use of the drug
    would lead to large weight loss: https://media.healthnews.com/images/featured/2023/04/Shutterstock_2247646277.jpg

    ... CPACC ... restricts the amount of magnesium
    delivered to the energy-producing parts of cells
    known as mitochondria.

    Although magnesium is a critical element for
    good health along with calcium, sodium, and
    potassium, too much magnesium can slow
    down the energy production in mitochondria,
    leading to less efficient sugar and fat metab-
    olism.

    When scientists deleted the gene MRS2 in mice
    that promotes magnesium absorption into the
    mitochondria, the rodent’s metabolism increased
    — resulting in weight loss and no sign of fatty liver
    disease. CPACC — a small, synthesized molecule —
    produces the same results.

    ... Although the results of this mouse study appear
    promising, the scientists still need to develop an
    MRS2-modulating molecule for research involving
    human participants.

    In addition, the study authors say that the MRS2
    channel is expressed widely throughout the body.
    Therefore, investigations are needed to examine
    the effects modulating MRS2 could have on other
    organs, including the brain, heart, kidneys, lungs,
    and muscles.

    On Thursday, March 23, 2023 at 3:07:26 PM UTC-5, _ wrote:

    1) The pill isn't a pill, it's injections, & it's
    thus far only been tested in mice.

    2) They are developing a pill version of
    the drug and hope to start human trials
    this year.

    3) The drug is not being developed to
    deal with Cellosis (new clarifying name
    for type 2 diabetes) but a side effect of
    the drug is reduction in risk of getting
    Cellosis.

    4) References to weight loss in the art-
    icle, unclear if the drug induces weight
    loss or simply prevents weight gain, so
    the "makes you skinny" part of the title
    may be exaggerating the actual impact
    of the drug.

    ---
    March 22 2023 https://www.dailymail.co.uk/health/article-11889987/Wonder-pill-makes-skinny-WITHOUT-dieting-exercising.html
    ---

    ... The drug — named CPACC — is a small
    molecule that works by inhibiting the uptake
    of magnesium by mitochondria in cells. The
    team is now looking to patent the drug, but
    warn it may still be years before it reaches
    pharmacies. ...

    ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~

    Pro-Humanist FREELOVER, Insulinitis (Islit)
    since age 5, got it in March 1961 https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    C.ure I.nsulinitis A.ssociation
    ASAP! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    The Sooner The Better! https://prohuman.net/glucoseanomaliesresearch.htm

    - - -

    The old confusing way which all-too-often
    involves folks using the diabetes / diabetic
    words without a clarifier:

    diabetes / diabetic without a clarifier,
    diabetes / diabetic guessing required https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg

    - - -

    Logic and reasoning behind ceasing using
    diabetes & diabetic & reactive hypoglycemia
    words and phrases, replacing all that with
    vastly superior names, ending diabetes &
    diabetic & reactive hypoglycemia confusion,
    misleading, & misunderstanding:

    Diabetes Bubble / Diabetes Bubble Burst
    Splendid! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    - - -

    Disparate High Glucose Conditions,
    DHGCs, 7 disparate categories of
    unpreventability / nonreversibility
    of all-but-one of the specific types
    of DHGCs (thus far, research actively
    trying to change that):

    o 15 specific types of rapid-onset Insul-
    initis (Islit), unpreventable & nonrevers-
    ible (thus far), the overwhelming majority
    with Islit have Insulitis Islit (sometimes
    called type 1 diabetes, often confusingly
    called diabetes with no clarifier) https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    14 specific types of Islit are not caused
    by Insulitis, present in a small minority
    of those with Islit.

    o 1 specific type of slow-onset Islit, Latent
    Autoimmune Islit, also unpreventable &
    nonreversible (thus far) (sometimes called
    latent autoimmune diabetes in adults, often
    confusingly called diabetes with no clarifier)

    o Preventable Cellosis is the only specific
    type of DHGC that is preventable & revers-
    ible (in many, sometimes it's called type 2
    diabetes, often confusingly called diabetes
    with no clarifier)

    Risk for Preventable Cellosis, Hypertension,
    & Cardiovascular Disease increases as one's
    weight increases but BMI risk increases at
    lower BMI levels in non-white individuals: https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
    https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html

    PreCellosis (often confusingly called pre-
    diabetes with no clarifier) is the oft-times
    preventable & reversible Cellosis precondi-
    tion that all-too-often the overwhelming ma-
    jority having it are unaware they have it

    o 20 specific types of Cellosis, unpreven-
    table & nonreversible (thus far, sometimes
    called type 2 diabetes, all-too-often con-
    fusingly called diabetes with no clarifier)

    o 1 specific type of DHGC only occurring
    in the late stage of impregnation in women,
    a type that's transient but that increases
    risk of later getting Cellosis, that ...

    ... condition called Gestational Cellosis
    (sometimes called gestational diabetes,
    sometimes confusingly called diabetes with
    no clarifier).

    o 11 specific types of Diminosis (new name
    created in 2010 for a monogenic condition
    age 6 months that sometimes is called
    maturity onset diabetes of the young, some-
    times confusingly called diabetes with no
    clarifier), unpreventable & non-reversible
    (thus far).

    o 12 specific types of Neonatal Diminosis
    (new name created in 2010 for a monogenic
    condition at age < or = 6 months that some-
    times is called neonatal diabetes, sometimes
    confusingly called diabetes with no ...

    ... clarifier), 8 types are permanent & unpre-
    ventable & nonreversible (thus far); 4 specific
    types are transient but can recur.

    o 25 specific types of Ohiglucons (new name
    created in 2010 for other diabetes mellitus,
    but often confusingly called diabetes with
    no clarifier).

    23 specific types are totally unpreventable.

    Hemochromatosis Ohiglucon, is only preventa-
    ble if Hemochromatosis is found and treated
    before it damages the pancreas.

    Immunosuppressants Ohiglucon, caused after
    a transplant with the required use of immun-
    osuppressants, 50% is temporary, but if it
    persists for over a year, most likely the condi-
    tion is permanent.

    If endogenous insulin production is near-totally
    to totally lost & does not recover after immuno-
    suppressants dosages reduced, it causes Im-
    munosuppressants Islit.

    - - -

    A mostly Non-Glucose Anomaly, Insipidus, it's
    also unpreventable & nonreversible (thus far):

    o 6 specific types of Insipidus (new name
    created in 2010 for diabetes insipidus, some-
    times confusingly called diabetes with no clar-
    ifier), 4 specific types don't include high glucose
    & are unpreventable & nonreversible (thus far),
    2 specific rare types do include high glucose &
    are unpreventable & nonreversible (thus far).

    - - -

    The following condition is apart from the
    diabetes confusion problem, but has confu-
    sion issues of its own.

    A Low Glucose Condition, Hut:

    o The 21 specific types of Hut (new name
    created in 2010 for Hypoglycemia Uncaused
    by Treatments for High Glucose, often con-
    fusingly called reactive hypoglycemia, con-
    fusing in that it does not occur as a reac-
    tion to treatment for High Glucose; one ...

    ... form sometimes called hyperinsulinism),
    some specific types are preventable & rever-
    sible, some aren't (thus far).

    - - -

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~

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