• Cutting calories can help you live longer, but how much should you cut?

    From _@21:1/5 to All on Sat Sep 11 12:36:04 2021
    The following study, small in size, studying only
    36 individuals who had BMI 25 to 29.9, what I
    refer to as "Ample" in the following graphic: https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg

    The study involved reducing calorie intake by
    25% per day. Note that studies show that the
    longest average lifespan occurs in those with
    an "Ample" BMI, though a disclaimer regarding
    that is many sick people lose weight, causing
    their weight to be less than BMI 25.

    Unclear what the percentages are of healthy
    people & sick people with BMI less than 25,
    but I suspect most with BMI less than 25 are
    in fact healthy, as are most with BMI 25 to 29.9.

    - - -
    September 11 2021 https://en.brinkwire.com/health/cutting-calories-can-help-you-live-longer-but-how-much-should-you-cut-study/
    - - -

    According to Pennington Biomedical Research
    Centre, research has shown that a calorie-re-
    stricted diet in non-obese adults leads to less
    muscle cell damage. It demonstrated how oxi-
    dative damage contributes to aging and possibly
    explain why calorie restriction without hunger
    increases life expectancy.

    - - - - - - - - -
    Insert

    Calorie restriction *without hunger*? Hmm, all
    the calorie restriction I've ever been involved
    with *included hunger*, so I'm not sure how
    they supposedly managed to do sot *without
    hunger* - I suspect they didn't actually do so.

    End Insert
    - - - - - - - - -

    Calorie consumption recommendations vary with
    age, metabolism, & level of physical activity, among
    other factors. According to the NHS, the recommen-
    ded daily calorie intake for women is 2,000 calories
    & for males is 2,500 calories.

    One of the study’s authors stated, “A calorie-restric-
    ted diet delivers all the elements necessary for a
    healthy life while minimizing the energy (calories)
    supplied in the diet.”

    The study’s key findings revealed that a calorie-re-
    stricted diet extends the lifespan of mice & delays
    the onset of age-related chronic diseases in rodents
    such as cancer, heart disease, and stroke.

    - - - - - - - - -
    Insert

    As always, mice & rodent data is interesting, but
    typically is of little relevance when it comes to
    humans, as evidenced by the innumerable mice
    'cures' for various Disparate High Glucose Condi-
    tions which don't do anything for humans.

    End Insert
    - - - - - - - - -

    There is additional evidence that those who follow a
    calorie-restricted diet live longer than those who over-
    eat. Furthermore, calorie-restricted diets have a posi-
    tive impact on a number of age-related variables, in-
    cluding decreasing insulin sensitivity, which can lead
    to (see insert)

    - - - - - - - - -
    Insert

    They used the word "diabetes", but actually, only Pre-
    ventable Cellosis has insulin resistance as the core
    cause of HbA1c 6.5 or >, & 20 unpreventable specific
    types of Cellosis & 6 Non-Cellosis Disparate High Glu-
    cose Conditions are *not* caused by insulin resistance
    issues.

    End Insert
    - - - - - - - - -

    The accumulation of “oxidative damage” – an imbalance
    of antioxidants – in the body’s proteins, lipids, and DNA,
    which could accelerate ageing, is a major element in the
    age-related deterioration of biological functions.

    In their study, 36 healthy "Ample" weight (BMI 25 to 29.9)
    young people were enrolled. A third of them got all of their
    energy from food; the caloric restriction group got 25% less
    calories; and the control group got 12.5 percent more calor-
    ies.

    - - - - - - - - -
    Insert

    I have no idea what "1/3rd got all their energy from food"
    means, as where else would one get their energy from
    unless they are saying they didn't get any energy from
    any liquids, I find their statement strange. Their 25% cal-
    orie restriction group & 12.5% more calories group, un-
    clear how many of the 36 were in each group.

    End Insert
    - - - - - - - - -

    The researchers discovered that a 25% caloric deficit for
    six months, accomplished either through diet or activity,
    reduced the number of calories burned during the day.

    A reduction in calories boosted the amount of mitochondria
    in muscles, according to the study’s examination of genes
    involved in cell development. Calorie restriction significantly
    lowered DNA damage in the muscles of the subjects, open-
    ing the way for longer life.

    The first barrier ... was locating patients ready to participate.
    After all, they’d have to reduce the size of their regular dish
    by 25% for each of the three meals.

    - - - - - - - - -
    Insert

    Why do folks presume people only eat 3 meals per day, &
    ignore snacking, something I suspect almost everyone does
    frequently?

    End Insert
    - - - - - - - - -

    “I’m not sure if you realize how difficult it is to perform calorie restriction every day,” she admits ... .

    - - - - - - - - -
    Insert

    I didn't understand the 'but “Brinkwire News in Condensed
    Form.” ' part of that last sentence, but in any case, I assure
    you, most are fully aware how difficult it is to perform calorie
    restriction every day. I know how difficult it is for me to do so,
    though I've been succeeding on well over 90% of days since
    I've been on my diet in which I've lost over 47 pounds in ...

    ... the last 7 months, going from BMI 29.8 down to BMI 22.2,
    weight 186 pounds down to 138.8 pounds at the current time.
    If anything less than 2,500 calories is considered calorie re-
    striction, I'd guess than I've only been at 2,500 calories or
    more for maybe 2 days out of the last 221 days (the diet
    starting on February 2), so that = 99.09% of the days.

    End Insert
    - - - - - - - - -

    Sidenote:

    I looked up the following study by researchers at the Penning-
    ton Biomedical Research Centre in Baton Rouge, it appears
    similar to the study referenced above - it may be the same
    study although the following article published March 29 2018
    says it's "the biggest-ever human study of calorie restriction."

    36 people doesn't seem big to me, so it may not be the same
    study as the following article doesn't mention how many were
    in the study.

    Will cutting calories actually make you live longer? https://www.gqindia.com/content/will-cutting-calories-actually-make-live-longer

    ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~

    The old confusing way which all-too-often
    involves folks using the diabetes / diabetic
    words without a clarifier:

    diabetes / diabetic without a clarifier,
    diabetes / diabetic guessing required
    https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg

    - - -

    Pro-Humanist FREELOVER, promoting
    since May 17 2010 putting an end to all
    outdated confusing misleading diabetes/
    diabetic ways of referring to each and all
    of Disparate High Glucose Conditions
    (DHGCs) and one mostly non-glucose ...

    ... anomaly and one low glucose anomaly
    which uses an outdated confusing reactive
    hypoglycemia term, ...
    https://prohuman.net/pix2/diabetesdiabeticconfusion.jpg
    https://prohuman.net/pix2/diabetesdiabeticendingthemisunderstanding.jpg

    ... replacing all of that with new superior
    clarifying medical terms which hopefully
    will end diabetes/diabetic/reactive hypo-
    glycemia confusion & misleading, putting
    an end to the use of those terms, totally:
    https://prohuman.net/pix2/diabetesbubblediabetesbubblebursttitle.jpg
    https://prohuman.net/pix2/diabetesreactivehypoglycemiaoldnamesnewnames.jpg
    https://prohuman.net/pix2/oldnamesnewimprovednames.jpg

    o There are 15 specific types of rapid onset
    Insulinitis (Islit). I've had Insulitis Islit (the pre-
    dominate type) since March 1961, age 5.
    https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    o There is 1 slow onset type of Islit, Latent
    Autoimmune Islit.

    o There are 21 specific types of the most
    widespread DHGC which is present in up to
    95% of those with any DHGC, Cellosis, new
    superior clarifying name for type 2 diabetes,
    its precondition is called PreCellosis.

    The only preventable/reversible DHGC is
    Preventable Cellosis, new clarifying specific
    type of the preventable type 2 diabetes, esti-
    mated to be the type that at least 85% of
    Americans with Cellosis have.

    Risk for Preventable Cellosis, Hypertension,
    & Cardiovascular Disease increases as one's
    weight increases but BMI risk increases at
    lower BMI levels in non-white individuals: https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
    https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html

    o There is 1 specific type of DHGC that
    happens in < 10% of pregnancies called
    Gestational Cellosis.

    o There are 11 specific types of diminished
    insulin production, monogenic conditions
    called Diminosis.

    o There are 12 specific type of diminished
    insulin production that occurs up to 6 months
    after birth, monogenic conditions called Neo-
    natal Diminosis.

    o There are 25 specific types of continued but
    problematic DHGCs called Ohiglucons (Other
    High Glucose Conditions).

    o There are 6 specific types of a mostly non-
    glucose anomaly called Insipidus.

    o There are 21 specific types of Hypoglycemia
    Uncaused by Treatments for High Glucose (Hut).

    Details on all of those DHGCs / a mostly non-
    glucose anomaly / a low glucose anomaly:

    Diabetes Bubble / Diabetes Bubble Burst
    Wonderful! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    C.ure I.nsulinitis A.ssociation
    Ideal! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    Hopefully! https://prohuman.net/glucoseanomaliesresearch.htm

    - - -

    Those who favor new terms, the following
    is inspirational:

    I Do Not Like Diabetes Here or There,
    I Do Not Like Diabetes Anywhere https://smile.amazon.com/Not-Like-Diabetes-Anywhere-shirt/dp/B01N25FMMI/ref=pd_d0_recs_v2_cwb_193_3?_encoding=UTF8&refRID=WJHV2S8X0YG21Z9WVQD5&th=1

    See No
    Speak No
    Hear No
    DIABETES
    Faith Will Make It So https://smile.amazon.com/CafePress-Speak-Diabetes-Unique-Coffee/dp/B014JS6QDI/ref=sr_1_2_sspa?s=home-garden&ie=UTF8&qid=1513534468&sr=1-2-spons&keywords=diabetes+cup&psc=1

    Syllables - Comparison of old
    diabetes terms / new terms https://prohuman.net/diabetesoldtermsnewtermssyllables.htm

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From _@21:1/5 to All on Sat Sep 11 13:19:14 2021
    (re-post fixing 1 mistake & including 3 additional
    clarifying comments)

    The article actually studies a 25% reduction in
    calories but doesn't specifically address how
    much you *should* cut.

    The following study, small in size, studying only
    36 individuals who had BMI 25 to 29.9, what I
    refer to as "Ample" in the following graphic: https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg

    The study involved reducing calorie intake by
    25% per day. Note that studies show that the
    longest average lifespan occurs in those with
    an "Ample" BMI, though a disclaimer regarding
    that is many sick people lose weight, causing
    their weight to be less than BMI 25.

    Unclear what the percentages are of healthy
    people & sick people with BMI less than 25,
    but I suspect most with BMI less than 25 are
    in fact healthy, as are most with BMI 25 to 29.9.

    - - -
    September 11 2021 https://en.brinkwire.com/health/cutting-calories-can-help-you-live-longer-but-how-much-should-you-cut-study/
    - - -

    According to Pennington Biomedical Research
    Centre, research has shown that a calorie-re-
    stricted diet in non-obese adults leads to less
    muscle cell damage. It demonstrated how oxi-
    dative damage contributes to aging and possibly
    explain why calorie restriction without hunger
    increases life expectancy.

    - - - - - - - - -
    Insert

    Calorie restriction *without hunger*? Hmm, all the
    calorie restriction I've ever been involved with *in-
    cluded hunger*, so I'm not sure how they suppos-
    edly managed to do *without hunger* - I suspect
    they didn't actually do so.

    End Insert
    - - - - - - - - -

    Calorie consumption recommendations vary with
    age, metabolism, & level of physical activity, among
    other factors. According to the NHS, the recommen-
    ded daily calorie intake for women is 2,000 calories
    & for males is 2,500 calories.

    One of the study’s authors stated, “A calorie-restric-
    ted diet delivers all the elements necessary for a
    healthy life while minimizing the energy (calories)
    supplied in the diet.”

    The study’s key findings revealed that a calorie-re-
    stricted diet extends the lifespan of mice & delays
    the onset of age-related chronic diseases in rodents
    such as cancer, heart disease, and stroke.

    - - - - - - - - -
    Insert

    As always, mice & rodent data is interesting, but typ-
    ically is of little relevance when it comes to humans,
    as evidenced by the innumerable mice 'cures' for var-
    ious Disparate High Glucose Conditions which don't
    do anything for humans.

    End Insert
    - - - - - - - - -

    There is additional evidence that those who follow a
    calorie-restricted diet live longer than those who over-
    eat. Furthermore, calorie-restricted diets have a posi-
    tive impact on a number of age-related variables, in-
    cluding decreasing insulin sensitivity, which can lead
    to (see insert)

    - - - - - - - - -
    Insert

    They used the word "diabetes", but actually, only Pre-
    ventable Cellosis has insulin resistance as the core
    cause of HbA1c 6.5 or >, & 20 unpreventable specific
    types of Cellosis & 6 Non-Cellosis Disparate High Glu-
    cose Conditions are *not* caused by insulin resistance
    issues.

    End Insert
    - - - - - - - - -

    The accumulation of “oxidative damage” – an imbalance
    of antioxidants – in the body’s proteins, lipids, and DNA,
    which could accelerate ageing, is a major element in the
    age-related deterioration of biological functions.

    In their study, 36 healthy "Ample" weight (BMI 25 to 29.9)
    young people were enrolled. A third of them got all energy
    from food; the caloric restriction group got 25% less calor-
    ies; and the control group got 12.5 percent more calories.

    - - - - - - - - -
    Insert

    I have no idea what "1/3rd got all their energy from food"
    means, as where else would one get their energy from
    unless they are saying they didn't get any energy from
    any liquids, I find their statement strange. Their 25% cal-
    orie restriction group & 12.5% more calories group, un-
    clear how many of the 36 were in each group.

    Also unclear why only 1/3rd got all their energy from
    food, and what the parameters were for the 2/3rds
    claimed to *not* get all their energy from food, & how
    many were in the 12.5% more calories group. Also,
    the article said nothing about the weight or other
    health impacts in the 12.5% more calories group.

    End Insert
    - - - - - - - - -

    The researchers discovered that a 25% caloric deficit for
    six months, accomplished either through diet or activity,
    reduced the number of calories burned during the day.

    A reduction in calories boosted the amount of mitochondria
    in muscles, according to the study’s examination of genes
    involved in cell development. Calorie restriction significantly
    lowered DNA damage in the muscles of the subjects, open-
    ing the way for longer life.

    The first barrier ... was locating patients ready to participate.
    After all, they’d have to reduce the size of their regular dish
    by 25% for each of the three meals.

    - - - - - - - - -
    Insert

    Why do folks presume people only eat 3 meals per day, &
    ignore snacking, something I suspect almost everyone does
    frequently?

    End Insert
    - - - - - - - - -

    “I’m not sure if you realize how difficult it is to perform calorie restriction every day,” she admits ... .

    - - - - - - - - -
    Insert

    I didn't understand the 'but “Brinkwire News in Condensed
    Form.” ' part of that last sentence, but in any case, I assure
    you, most are fully aware how difficult it is to perform calorie
    restriction every day. I know how difficult it is for me to do so,
    though I've been succeeding on well over 90% of days since
    I've been on my diet in which I've lost over 47 pounds in ...

    ... the last 7 months, going from BMI 29.8 down to BMI 22.2,
    weight 186 pounds down to 138.8 pounds currently. If any-
    thing less than 2,500 calories is considered calorie restric-
    tion, I'd guess than I've only been at 2,500 calories or more
    for maybe 2 days out of the last 221 days (the diet starting
    on February 2 2021), so that = 99.09% of the days.

    End Insert
    - - - - - - - - -

    Sidenote:

    I looked up the following study by researchers at the Penning-
    ton Biomedical Research Centre in Baton Rouge, it appears
    similar to the study referenced above - it may be the same
    study although the following article published March 29 2018
    says it's “the biggest-ever human study of calorie restriction.”

    36 people doesn't seem big to me, so it may not be the same
    study as the following article doesn't mention how many were
    in the study. However, the above study mentioned 6 months,
    unclear if it lasted longer, but the following study mentioned
    2 years.

    Will cutting calories actually make you live longer? https://www.gqindia.com/content/will-cutting-calories-actually-make-live-longer

    Two interesting excerpts:

    ... Studies going back to the mid-1930s have shown over and
    over that cutting calories by 25-50 per cent lets yeast, worms,
    mice, rats, and monkeys live longer, healthier lives, free from
    age-related disease.

    ... “Restricting calories can slow your basal metabolic rate
    --the energy you need to sustain all normal daily functions. ...
    When the body uses less oxygen to generate all its required
    energy, it produces fewer byproducts of metabolism, things
    like free radicals that can damage DNA and other cellular
    machinery. After two years, the lower rate of metabolism ...

    ... and level of calorie restriction was linked to a reduction
    in oxidative damage to cells and tissues.”

    ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~

    The old confusing way which all-too-often
    involves folks using the diabetes / diabetic
    words without a clarifier:

    diabetes / diabetic without a clarifier,
    diabetes / diabetic guessing required https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg

    - - -

    Pro-Humanist FREELOVER, promoting
    since May 17 2010 putting an end to all
    outdated confusing misleading diabetes/
    diabetic ways of referring to each and all
    of Disparate High Glucose Conditions
    (DHGCs) and one mostly non-glucose ...

    ... anomaly and one low glucose anomaly
    which uses an outdated confusing reactive
    hypoglycemia term, ...
    https://prohuman.net/pix2/diabetesdiabeticconfusion.jpg https://prohuman.net/pix2/diabetesdiabeticendingthemisunderstanding.jpg

    ... replacing all of that with new superior
    clarifying medical terms which hopefully
    will end diabetes/diabetic/reactive hypo-
    glycemia confusion & misleading, putting
    an end to the use of those terms, totally: https://prohuman.net/pix2/diabetesbubblediabetesbubblebursttitle.jpg https://prohuman.net/pix2/diabetesreactivehypoglycemiaoldnamesnewnames.jpg https://prohuman.net/pix2/oldnamesnewimprovednames.jpg

    o There are 15 specific types of rapid onset
    Insulinitis (Islit). I've had Insulitis Islit (the pre-
    dominate type) since March 1961, age 5. https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

    o There is 1 slow onset type of Islit, Latent
    Autoimmune Islit.

    o There are 21 specific types of the most
    widespread DHGC which is present in up to
    95% of those with any DHGC, Cellosis, new
    superior clarifying name for type 2 diabetes,
    its precondition is called PreCellosis.

    The only preventable/reversible DHGC is
    Preventable Cellosis, new clarifying specific
    type of the preventable type 2 diabetes, esti-
    mated to be the type that at least 85% of
    Americans with Cellosis have.

    Risk for Preventable Cellosis, Hypertension,
    & Cardiovascular Disease increases as one's
    weight increases but BMI risk increases at
    lower BMI levels in non-white individuals: https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
    https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html

    o There is 1 specific type of DHGC that
    happens in < 10% of pregnancies called
    Gestational Cellosis.

    o There are 11 specific types of diminished
    insulin production, monogenic conditions
    called Diminosis.

    o There are 12 specific type of diminished
    insulin production that occurs up to 6 months
    after birth, monogenic conditions called Neo-
    natal Diminosis.

    o There are 25 specific types of continued but
    problematic DHGCs called Ohiglucons (Other
    High Glucose Conditions).

    o There are 6 specific types of a mostly non-
    glucose anomaly called Insipidus.

    o There are 21 specific types of Hypoglycemia
    Uncaused by Treatments for High Glucose (Hut).

    Details on all of those DHGCs / a mostly non-
    glucose anomaly / a low glucose anomaly:

    Diabetes Bubble / Diabetes Bubble Burst
    Wonderful! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

    C.ure I.nsulinitis A.ssociation
    Ideal! https://prohuman.net/cureinsulinitisassociation.htm

    Glucose Anomalies Research regarding
    Potential Cures / Improvements in Treatments
    Hopefully! https://prohuman.net/glucoseanomaliesresearch.htm

    - - -

    Those who favor new terms, the following
    is inspirational:

    I Do Not Like Diabetes Here or There,
    I Do Not Like Diabetes Anywhere https://smile.amazon.com/Not-Like-Diabetes-Anywhere-shirt/dp/B01N25FMMI/ref=pd_d0_recs_v2_cwb_193_3?_encoding=UTF8&refRID=WJHV2S8X0YG21Z9WVQD5&th=1

    See No
    Speak No
    Hear No
    DIABETES
    Faith Will Make It So https://smile.amazon.com/CafePress-Speak-Diabetes-Unique-Coffee/dp/B014JS6QDI/ref=sr_1_2_sspa?s=home-garden&ie=UTF8&qid=1513534468&sr=1-2-spons&keywords=diabetes+cup&psc=1

    Syllables - Comparison of old
    diabetes terms / new terms https://prohuman.net/diabetesoldtermsnewtermssyllables.htm

    Stop Diabetes/Diabetic Confusion
    with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

    ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~ ~!~

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)