Glucose-aware insulin, a goal that has been
aspired to by many companies over the years,
I rarely read any articles about progress in this
area, & the articles are reluctant to call smart
glucose-aware insulin a 'cure', despite its pur-
ported capability to avoid hypoglycemia -and-
hyperglycemia.

Here's a bit of research on a synthetic insulin
hinge being worked on by Michael A. Weiss,
MD, a prominent professor at Indiana University
School of Medicine.

- - -
August 2 2021 https://floridanewstimes.com/synthetic-hinges-can-hold-the-key-to-innovative-smart-insulin-therapy/316821/
- - -

The article mentions glucose levels 70 mg/dl as a
'turn-off' point -and- 180 mg/dl as a 'turn-on' point,
but actually, in folks with a fully functional pancreas,
insulin 'turns off' at 83 mg/dl & assorted endogenous
hormonal reactions transpire to prevent hypoglycemia.

Also, endogenous insulin responds immediately to
glucose rises at sub-100 mg/dl & prevents almost all
glucose rises > 140 mg/dl, never allowing glucose lev-
els to go above 180 mg/dl, per the following post of
153 individuals who have fully functional pancreases
(i.e., no Disparate High Glucose Condition), ages 7 to
80 ... https://groups.google.com/g/misc.health.diabetes/c/4E_1OM3ZzSk/m/LIj0zVsWAwAJ

... here's what their glucose levels were with up to 10
days of wearing a 'blinded' Dexcom G6 continuous
glucose monitor (CGM), i.e., the 153 individuals did
not view their glucose levels:

% of glucose levels > 180 mg/dL ... 0%
% of glucose levels 160.1 to 180 mg/dl ... 3/10ths of 1%
% of glucose levels 140.1 to 160 mg/dl ... 2.1%
% of glucose levels 70 to 140 mg/dl ... 96%
% of glucose levels 70 to 120 mg/dl ... 89%
% of glucose levels 60 to 69.9 mg/dl ... 1.1%
% of glucose levels 54 to 59.9 mg/dl ... 2/10ths of 1%
% of glucose levels < 54 mg/dl ... 0%

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For clarity about the -7- Disparate High Glucose
Conditions (DHGCs) with -85- specific types, refer
to the following:
https://prohuman.net/diabetesbubblediabetesbubbleburst.htm https://prohuman.net/pix2/diabetesbubblediabetesbubblebursttitle.jpg https://prohuman.net/pix2/diabetesreactivehypoglycemiaoldnamesnewnames.jpg https://prohuman.net/pix2/oldnamesnewimprovednames.jpg

Also, -6- specific types of a mostly non-glucose
anomaly Insipidus -and- -21- specific types of
Hypoglycemia Uncaused by Treatments for
High Glucose (Hut) are fully explained at the
following, beauteous bountiful Knowledge &
Power:

Everything You Ever Wanted to Know about
DHGCs, Insipidus, & Hut, but were afraid to
ask (or due to diabetes confusion, not knowing
enough to ask):
https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

- - -

Stop Diabetes/Diabetic Confusion
with New Superior Clarifying Terms https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

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