Diet type can increase potentially harmful gas in the gut
Date:
May 3, 2022
Source:
University of Minnesota Medical School
Summary:
Scientists looked at colonic hydrogen sulfide -- a toxic gas in
the body that smells like rotten eggs -- production in people in
response to animal- and plant-based diet interventions.
FULL STORY ========================================================================== Published in Clinical Nutrition, researchers from the University of
Minnesota Medical School looked at colonic hydrogen sulfide -- a toxic
gas in the body that smells like rotten eggs -- production in people in response to animal- and plant-based diet interventions.
========================================================================== "Although the role of hydrogen sulfide has long been a subject of great interest in the pathogenesis of multiple important diseases -- such as ulcerative colitis, colon cancer, and obesity -- past investigations
have not been able to link dietary data, microbiome characterization
and actual hydrogen sulfide production," said Alexander Khoruts,
MD, a gastroenterologist in the U of M Medical School and M Health
Fairview. "This is what we have done here." From a human cohort, the
study supports the general hypothesis that hydrogen sulfide produced by
the gut microbiota increases with an animal-based diet.
However, the results also suggested the existence of gut microbiome
enterotypes that respond differentially and even paradoxically to
different dietary input.
The study found that:
* In the majority of participants, a plant-based diet resulted in
a lower
hydrogen sulfide production compared to an animal-based (i.e.,
western) diet.
* As expected, a plant-based diet contained more fiber, while
an animal-
based diet contained more protein.
* In some individuals, plant-based diets did not lower hydrogen
sulfide
production and even led to some increases in it.
* Preliminary results suggested the existence of different
compositions of
gut microbiota (enterotypes) that correlate with differential
responsiveness to diet in terms of hydrogen sulfide production.
"The study was consistent with the general understanding that regular
intake of fiber-containing foods is beneficial to gut health,"
said Dr. Levi Teigen, a nutrition researcher in the Division of Gastroenterology in the U of M Medical School. "Future analyses of
the gut microbiome may help to individualize nutrition interventions."
The study was funded by Healthy Foods Healthy Lives, Achieving Cures
Together, the Allen Foundation and the University of Minnesota MnDRIVE Initiative. The research team envisions future work that will lead
to more personalized nutritional counseling that will be informed by microbiome-based diagnostics.
========================================================================== Story Source: Materials provided by
University_of_Minnesota_Medical_School. Original written by Kat
Dodge. Note: Content may be edited for style and length.
========================================================================== Journal Reference:
1. Levi Teigen, Prince P. Mathai, Sharon Lopez, Michael Matson,
Baila Elkin,
Daria Kozysa, Amanda J. Kabage, Matthew Hamilton, Byron P. Vaughn,
Michael J. Sadowsky, Alexander Khoruts. Differential hydrogen
sulfide production by a human cohort in response to animal- and
plant-based diet interventions. Clinical Nutrition, 2022; 41 (6):
1153 DOI: 10.1016/ j.clnu.2022.03.028 ==========================================================================
Link to news story:
https://www.sciencedaily.com/releases/2022/05/220503190209.htm
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